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HK1159119B - Method for preserving polypeptides using a sugar and polyethyleneimine - Google Patents

Method for preserving polypeptides using a sugar and polyethyleneimine Download PDF

Info

Publication number
HK1159119B
HK1159119B HK11113381.7A HK11113381A HK1159119B HK 1159119 B HK1159119 B HK 1159119B HK 11113381 A HK11113381 A HK 11113381A HK 1159119 B HK1159119 B HK 1159119B
Authority
HK
Hong Kong
Prior art keywords
polyethyleneimine
sugar
preserving
polypeptides
polypeptide
Prior art date
Application number
HK11113381.7A
Other languages
Chinese (zh)
Other versions
HK1159119A1 (en
Inventor
Drew Jeffrey
Original Assignee
Stabilitech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0817527A external-priority patent/GB0817527D0/en
Priority claimed from GB0817524A external-priority patent/GB0817524D0/en
Priority claimed from GB0817526A external-priority patent/GB0817526D0/en
Priority claimed from GB0817525A external-priority patent/GB0817525D0/en
Application filed by Stabilitech Ltd filed Critical Stabilitech Ltd
Priority claimed from PCT/GB2009/002283 external-priority patent/WO2010035001A1/en
Publication of HK1159119A1 publication Critical patent/HK1159119A1/en
Publication of HK1159119B publication Critical patent/HK1159119B/en

Links

Abstract

A method for preserving a polypeptide comprises (i) providing an aqueous solution of one or more sugars, a polyethyleneimine and said polypeptide wherein the concentration of polyethyleneimine is 25 μM or less based on the number-average molar mass (Mn) of the polyethyleneimine and the sugar concentration or, if more than one sugar is present, total sugar concentration is greater than 0.1 M; and (ii) drying the solution to form an amorphous solid matrix comprising said polypeptide.
HK11113381.7A 2008-09-24 2009-09-24 Method for preserving polypeptides using a sugar and polyethyleneimine HK1159119B (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GB0817527A GB0817527D0 (en) 2008-09-24 2008-09-24 Method for preserving enzymes
GB0817524A GB0817524D0 (en) 2008-09-24 2008-09-24 Method for preserving vaccine immunogens
GB0817525.9 2008-09-24
GB0817526.7 2008-09-24
GB0817526A GB0817526D0 (en) 2008-09-24 2008-09-24 Method for preserving polypeptides
GB0817527.5 2008-09-24
GB0817525A GB0817525D0 (en) 2008-09-24 2008-09-24 Method for preserving antibodies
GB0817524.2 2008-09-24
PCT/GB2009/002283 WO2010035001A1 (en) 2008-09-24 2009-09-24 Method for preserving polypeptides using a sugar and polyethyleneimine

Publications (2)

Publication Number Publication Date
HK1159119A1 HK1159119A1 (en) 2012-07-27
HK1159119B true HK1159119B (en) 2013-01-18

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