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HK1143379B - 半胱氨酸改造的抗tenb2抗體和抗體藥物共軛物 - Google Patents

半胱氨酸改造的抗tenb2抗體和抗體藥物共軛物 Download PDF

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Publication number
HK1143379B
HK1143379B HK10109905.3A HK10109905A HK1143379B HK 1143379 B HK1143379 B HK 1143379B HK 10109905 A HK10109905 A HK 10109905A HK 1143379 B HK1143379 B HK 1143379B
Authority
HK
Hong Kong
Prior art keywords
antibody
tenb2
cancer
cysteine engineered
cysteine
Prior art date
Application number
HK10109905.3A
Other languages
German (de)
English (en)
French (fr)
Other versions
HK1143379A1 (zh
Inventor
Weiguang Mao
Jagath Reddy Junutula
Paul Polakis
Original Assignee
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech, Inc. filed Critical Genentech, Inc.
Priority claimed from PCT/US2008/080102 external-priority patent/WO2009052249A1/en
Publication of HK1143379A1 publication Critical patent/HK1143379A1/zh
Publication of HK1143379B publication Critical patent/HK1143379B/zh

Links

HK10109905.3A 2007-10-19 2008-10-16 半胱氨酸改造的抗tenb2抗體和抗體藥物共軛物 HK1143379B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98141107P 2007-10-19 2007-10-19
US60/981,411 2007-10-19
PCT/US2008/080102 WO2009052249A1 (en) 2007-10-19 2008-10-16 Cysteine engineered anti-tenb2 antibodies and antibody drug conjugates

Publications (2)

Publication Number Publication Date
HK1143379A1 HK1143379A1 (zh) 2010-12-31
HK1143379B true HK1143379B (zh) 2014-08-01

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