[go: up one dir, main page]

HK1032394A1 - 用於hiv感染之治療的經三取代之1,3,5-三嗪衍生物 - Google Patents

用於hiv感染之治療的經三取代之1,3,5-三嗪衍生物 Download PDF

Info

Publication number
HK1032394A1
HK1032394A1 HK01102801A HK01102801A HK1032394A1 HK 1032394 A1 HK1032394 A1 HK 1032394A1 HK 01102801 A HK01102801 A HK 01102801A HK 01102801 A HK01102801 A HK 01102801A HK 1032394 A1 HK1032394 A1 HK 1032394A1
Authority
HK
Hong Kong
Prior art keywords
amino
phenoxy
anilino
methyl
compound
Prior art date
Application number
HK01102801A
Other languages
German (de)
English (en)
French (fr)
Other versions
HK1032394B (zh
Inventor
Frans Desire Daeyaert Frederik
De Corte Bart
Rene De Jonge Marc
Heeres Jan
Yung Ho Chih
Adriaan Jan Janssen Paul
W. Kavash Robert
Maria Henricus Koymans Lucien
Joseph Kukla Michael
William Ludovici Donald
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of HK1032394A1 publication Critical patent/HK1032394A1/zh
Publication of HK1032394B publication Critical patent/HK1032394B/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40Nitrogen atoms
    • C07D251/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40Nitrogen atoms
    • C07D251/48Two nitrogen atoms
    • C07D251/50Two nitrogen atoms with a halogen atom attached to the third ring carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40Nitrogen atoms
    • C07D251/48Two nitrogen atoms
    • C07D251/52Two nitrogen atoms with an oxygen or sulfur atom attached to the third ring carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40Nitrogen atoms
    • C07D251/54Three nitrogen atoms
    • C07D251/66Derivatives of melamine in which a hetero atom is directly attached to a nitrogen atom of melamine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40Nitrogen atoms
    • C07D251/54Three nitrogen atoms
    • C07D251/70Other substituted melamines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK01102801.4A 1998-03-27 1999-03-24 用於hiv感染之治疗的经三取代之1,3,5-三嗪衍生物 HK1032394B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7963398P 1998-03-27 1998-03-27
US79633P 1998-03-27
EP98201589A EP0945447A1 (en) 1998-03-27 1998-05-14 Trisubstituted 1,3,5-triazine derivatives for treatment of HIV infections
EP98201589 1998-05-14
PCT/EP1999/002044 WO1999050256A1 (en) 1998-03-27 1999-03-24 Trisubstituted 1,3,5-triazine derivatives for treatment of hiv infections

Publications (2)

Publication Number Publication Date
HK1032394A1 true HK1032394A1 (zh) 2001-07-20
HK1032394B HK1032394B (zh) 2005-10-21

Family

ID=

Also Published As

Publication number Publication date
PT1066269E (pt) 2005-09-30
AP1475A (en) 2005-10-03
US6150360A (en) 2000-11-21
NO317425B1 (no) 2004-10-25
DE69925256D1 (de) 2005-06-16
ES2243056T3 (es) 2005-11-16
ATE295355T1 (de) 2005-05-15
WO1999050256A1 (en) 1999-10-07
NO20004809L (no) 2000-11-24
EP1066269B1 (en) 2005-05-11
US6774235B2 (en) 2004-08-10
AP2000001913A0 (en) 2000-09-30
BR9909197A (pt) 2000-12-05
NZ506787A (en) 2003-02-28
EA200000993A1 (ru) 2001-04-23
KR100593396B1 (ko) 2006-06-28
AR018169A1 (es) 2001-10-31
AU758624C (en) 2004-03-11
PL343195A1 (en) 2001-07-30
TR200002761T2 (tr) 2001-01-22
EA004540B1 (ru) 2004-06-24
AU3599799A (en) 1999-10-18
CN1157386C (zh) 2004-07-14
US20020115668A1 (en) 2002-08-22
ZA200006042B (en) 2001-10-26
US6372729B1 (en) 2002-04-16
HUP0101372A2 (hu) 2001-10-28
HRP20000621A2 (en) 2001-04-30
DK1066269T3 (da) 2005-09-05
DE69925256T2 (de) 2006-02-23
JP2002511390A (ja) 2002-04-16
CA2324921C (en) 2009-05-12
NO20004809D0 (no) 2000-09-26
EE200000535A (et) 2002-04-15
IL138670A (en) 2005-12-18
SI1066269T1 (en) 2005-10-31
BG104716A (en) 2001-04-30
BG64903B1 (bg) 2006-08-31
CA2324921A1 (en) 1999-10-07
PL194660B1 (pl) 2007-06-29
ID26043A (id) 2000-11-16
EP0945447A1 (en) 1999-09-29
AU758624B2 (en) 2003-03-27
CN1295566A (zh) 2001-05-16
OA11493A (en) 2004-05-07
SK14052000A3 (sk) 2001-06-11
HUP0101372A3 (en) 2003-02-28
EP1066269A1 (en) 2001-01-10
KR20010034270A (ko) 2001-04-25
TW570917B (en) 2004-01-11

Similar Documents

Publication Publication Date Title
EP1066269B1 (en) Trisubstituted 1,3,5-triazine derivatives for treatment of hiv infections
EP0834507B1 (en) Substituted diamino-1,3,5-triazine derivatives
AU751573B2 (en) HIV inhibiting pyrimidine derivatives
US20060049177A1 (en) Induction heating cooker
HK1032394B (zh) 用於hiv感染之治疗的经三取代之1,3,5-三嗪衍生物
MXPA00009436A (en) Trisubstituted 1,3,5-triazine derivatives for treatment of hiv infections
HK1009676B (zh) 取代的二氨基-1,3, 5-三嗪衍生物
CZ20003398A3 (cs) Deriváty trisubstituovaného 1,3,5-triazinu pro léčbu infekcí HIV

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090324