[go: up one dir, main page]

HK1011690A1 - 氟烷氧基取代的苯甲酰胺类化合物及其作为环状核苷酸磷酸二酯酶抑制剂的用途 - Google Patents

氟烷氧基取代的苯甲酰胺类化合物及其作为环状核苷酸磷酸二酯酶抑制剂的用途 Download PDF

Info

Publication number
HK1011690A1
HK1011690A1 HK98112932A HK98112932A HK1011690A1 HK 1011690 A1 HK1011690 A1 HK 1011690A1 HK 98112932 A HK98112932 A HK 98112932A HK 98112932 A HK98112932 A HK 98112932A HK 1011690 A1 HK1011690 A1 HK 1011690A1
Authority
HK
Hong Kong
Prior art keywords
halogen
alkoxy
hydrogen
compounds
alkyl
Prior art date
Application number
HK98112932A
Other languages
German (de)
English (en)
French (fr)
Other versions
HK1011690B (zh
Inventor
Amschler Hermann
Flockerzi Dieter
Gutterer Beate
Hatzelmann Armin
Schudt Christian
Beume Rolf
Kilian Ulrich
P. O. Wolf Horst
Original Assignee
Takeda Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4223466&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1011690(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Gmbh filed Critical Takeda Gmbh
Publication of HK1011690A1 publication Critical patent/HK1011690A1/zh
Publication of HK1011690B publication Critical patent/HK1011690B/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/56Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK98112932.9A 1993-07-02 1994-07-02 氟烷氧基取代的苯甲酰胺类化合物及其作为环状核苷酸磷酸二酯酶抑制剂的用途 HK1011690B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH199693 1993-07-02
CH1996/93-9 1993-07-02
PCT/EP1994/002169 WO1995001338A1 (de) 1993-07-02 1994-07-02 Fluoralkoxy substituierte benzamide und ihre verwendung als zyklisch-nukleotid phosphodiesterase-inhibitoren

Publications (2)

Publication Number Publication Date
HK1011690A1 true HK1011690A1 (zh) 1999-07-16
HK1011690B HK1011690B (zh) 2002-10-11

Family

ID=

Also Published As

Publication number Publication date
DK0706513T3 (da) 2002-09-09
NO955211L (no) 1995-12-21
HU9503541D0 (en) 1996-02-28
NO305598B1 (no) 1999-06-28
CA2165192A1 (en) 1995-01-12
CY2010015I2 (el) 2011-02-02
CA2165192C (en) 2001-04-24
NO2010018I1 (no) 2010-10-18
NO2010018I2 (zh) 2011-10-17
PL311820A1 (en) 1996-03-18
JPH08512041A (ja) 1996-12-17
KR960703400A (ko) 1996-08-17
SK283263B6 (sk) 2003-04-01
FI112864B (fi) 2004-01-30
HU220041B (hu) 2001-10-28
AU7490794A (en) 1995-01-24
DE59410119D1 (de) 2002-06-20
SK161795A3 (en) 1996-07-03
KR100331255B1 (ko) 2002-10-25
NO955211D0 (no) 1995-12-21
SI0706513T1 (en) 2002-10-31
EP0706513B1 (de) 2002-05-15
ATE217612T1 (de) 2002-06-15
CZ196A3 (en) 1996-06-12
FR10C0052I1 (zh) 2011-01-14
EP0706513A1 (de) 1996-04-17
HUT73232A (en) 1996-07-29
PL178314B1 (pl) 2000-04-28
NZ271316A (en) 1997-11-24
AU687087B2 (en) 1998-02-19
CN1046939C (zh) 1999-12-01
CN1126468A (zh) 1996-07-10
ES2176252T3 (es) 2002-12-01
CY2010015I1 (el) 2011-02-02
PT706513E (pt) 2002-10-31
LU91709I2 (fr) 2010-09-21
US5712298A (en) 1998-01-27
CZ290266B6 (cs) 2002-06-12
FI956333A0 (fi) 1995-12-29
CY2389B1 (en) 2004-09-10
DE122010000043I1 (de) 2011-01-27
FR10C0052I2 (zh) 2011-11-25
LV13074B (en) 2004-03-20
SG143011A1 (en) 2008-06-27
FI956333A7 (fi) 1995-12-29
RU2137754C1 (ru) 1999-09-20
WO1995001338A1 (de) 1995-01-12
JP3093271B2 (ja) 2000-10-03

Similar Documents

Publication Publication Date Title
US5712298A (en) Fluoroalkoxy-substituted benzamides and their use as cyclic nucleotide phosphodiesterase inhibitors
JP4146894B2 (ja) ジヒドロベンゾフラン
US8536206B2 (en) Process for the preparation of roflumilast
DE69720493T2 (de) Naphthyridin-derivate
US5902824A (en) Phenyldihydrobenzofuranes
SK121698A3 (en) Triaryl compounds, preparation method and use thereof
EP1007512B1 (en) Branched alkoxy-subsituted 2-aminopyridines as nos inhibitors
CN116768815B (zh) 靛红酸酐类化合物及其制备方法和用途
HK1011690B (zh) 氟烷氧基取代的苯甲酰胺类化合物及其作为环状核苷酸磷酸二酯酶抑制剂的用途
JPH0324064A (ja) 1―フェニル―1,4―ジヒドロ―3―アミノ―4―オキソピリダジン誘導体、その製造法および治療用途
WO2016128905A1 (en) Thienopyrrole compounds as s-nitrosoglutathione reductase inhibitors
US6306867B1 (en) Imidazo- and oxazolopyridines
JP4638736B2 (ja) 新規のベンゾナフチリジン
HK1085480B (zh) 制备罗氟司特的方法
JPH03261765A (ja) ピリドン誘導体及びその製造方法

Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20140701