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Application filed by Sicor Inc.filedCriticalSicor Inc.
Publication of HK1070901ApublicationCriticalpatent/HK1070901A/en
An improved stereoselective process for the preparation of 6alpha-fluoropregnane derivatives of formula (I), comprising the reaction of 3-benzoyloxy-Delta3,5-pregnane derivatives of formula (II), with an electrophilic fluorination agent in a substantially water-free reaction mixture and in the presence of a salt of a strong acid with a nitrogenous base.
HK05103913.3A2002-12-092003-12-02Process for the preparation of pregnanes
HK1070901A
(en)