HK1067038A - Stable pressurized antiperspirant compositions containing dimethylether propellant and a low polarity solvent - Google Patents

Description

Stable pressurized antiperspirant compositions comprising dimethyl ether propellant and low polarity solvent

Technical Field

The present invention relates to pressurized antiperspirant compositions comprising a solubilized antiperspirant active, a dimethyl ether propellant and a low polarity solvent. The composition can be formulated as a stable single phase or clear pressurized liquid without the addition of ethanol, propylene glycol or aqueous solvents.

Background

A variety of pressurized antiperspirant formulations are known for controlling or inhibiting underarm perspiration and underarm malodor. Most of these formulations include antiperspirant powders, such as aluminum salts, suspended in an anhydrous carrier, mixed with a liquefied volatile propellant in a pressurized container. The formulation is applied to the underarm as a pressurized spray which results from the rapid boiling of the propellant under the combined action of the atomizing nozzle and the pressurized container.

Despite the convenience of aerosol antiperspirants that many consumers prefer, many aerosol dosage forms contain highly undesirable application cosmetics. Activation of these aerosols often results in application of a powder or powder, resulting in a heavy white residue at the application site on the skin. Furthermore, the powdery residue on the skin surface is relatively prone to flaking or falling off after application, especially when the application site is in contact with clothing, resulting in undesirable residues on the clothing, and loss or reduced coverage of the antiperspirant on the skin at the application site due to flaking or falling off of the product.

In order to improve the application of cosmetics, aerosol antiperspirant formulations have been designed which dissolve or solubilize the antiperspirant active in a suitable aqueous or anhydrous carrier. Many of these formulations are also single phase systems that do not contain any dispersed or suspended solids and therefore produce little or no visible residue at the site of application due to the deposition of dispersed or suspended solids. These single phase formulations often have a clear or translucent appearance and can be cleanly applied by aerosol spray without producing a powder or powder application. However, many such single phase aerosol dosage forms contain ethanol or water to aid in the solubilization of the antiperspirant active, thereby allowing for the formulation of a stable, single phase system. During use, the aqueous formula can cause a person to feel wet; during and after use, the ethanol containing formulations can irritate or sting the skin in sensitive underarm areas.

Another single phase antiperspirant aerosol is also described in the antiperspirant art. Wherein the single-phase aerosol is prepared by mixing dimethyl ether, a dissolved antiperspirant active substance and a polyalcohol solvent (such as propylene glycol). These compositions contain dimethyl ether to allow the preparation of stable single phase systems, provided that the system also contains water, ethanol or relatively high concentrations of propylene glycol to maintain the stability of the single phase system. However, such compositions tend to be unstable when large amounts of low polarity solvents are used, thus resulting in precipitation or phase separation of the antiperspirant active from solution shortly after manufacture, unless the complex is adjusted to contain relatively high concentrations of ethanol, water or propylene glycol. As is known in the antiperspirant art, high concentrations of ethanol or propylene glycol can irritate or sting the skin in sensitive underarm areas during or after use; high concentrations of water can cause an uncomfortable wet feeling of the skin.

It has now been found that pressurized antiperspirant products can be made as single phase or clear products without relying on high concentrations of ethanol, propylene glycol or water to solubilize or couple the antiperspirant active to the various ingredients to form a single phase or clear system. It has been found that a single phase pressurized antiperspirant can be prepared without relying on such materials, provided that it comprises an antiperspirant active dissolved in a polyol solvent; the polyol contains at least four carbon atoms and has one hydroxyl group on each of the alpha and beta carbon atoms. Wherein the solubilized active material and selected polyol solvent are combined with a dimethyl ether propellant, a low polarity solvent having a solubility parameter of less than about 0.8. Wherein the weight ratio of dimethyl ether to low polarity solvent is from about 0.1 to about 0.3.

It has been found that pressurized single phase antiperspirant products remain stable for extended periods of time if the defined polyol solvent and dimethyl ether propellant are coupled to a low polarity solvent, and if the weight ratio of dimethyl ether propellant to low polarity solvent remains within the ranges defined herein.

It has also been found that pressurized antiperspirant products as described above remain stable for long periods of time and can be formulated with low polarity solvents or materials into clear or single phase systems. These low polarity solvents or materials may include, for example, volatile or nonvolatile silicone fluids which can provide additional advantages such as high substantivity, emolliency, improved skin feel during or after use, formulation flexibility, and many other similar advantages. These low polarity solvents also include liquefied hydrocarbon propellants, which provide a low cost option compared to more expensive propellants.

Summary of The Invention

The present invention relates to a pressurized anhydrous antiperspirant composition comprising: (a) a polyol solvent having at least four carbon atoms, and the polyol having one hydroxyl group on each of the alpha and beta carbons. (b) Solubilized antiperspirant active. (c) Dimethyl ether (d) a low polarity liquid having a solubility parameter less than about 8. Wherein the weight ratio of dimethyl ether to low polarity solvent is from about 0.1 to about 3.0.

These compositions have been found to be particularly beneficial in formulating clear or single phase pressurized antiperspirant compositions which are stable over long periods of time and do not require high concentrations of ethanol, propanol or aqueous solvents. These compositions have also been found to remain single phase or clear even when mixed with low polarity solvents such as silicone oils, liquefied hydrocarbon propellants or other similar materials.

Detailed Description

The pressurized antiperspirant compositions of the present invention comprise a selected polyol solvent, a solubilized antiperspirant active, a dimethyl ether propellant, and a low polarity solvent in a defined proportion by weight to the dimethyl ether propellant. These and other essential elements or limitations of the pressurized antiperspirant of the present invention are detailed later herein.

Unless otherwise indicated, the term "anhydrous" as used herein refers to compositions or materials that contain less than about 5% free or added water by weight, more preferably less than about 3%, even more preferably less than about 1%, and even more preferably zero.

The term "ambient conditions" herein refers to ambient conditions at a pressure of about one atmosphere, a relative humidity of about 50%, and a temperature of about 25 ℃.

The term "pressurized antiperspirant" herein means any small package antiperspirant composition pressurized with a gaseous or liquefied propellant that provides a means for propelling or moving the antiperspirant composition through an application device.

All percentages, parts and ratios herein are by weight of the total composition, unless otherwise specified. All weights associated with listed ingredients are based on the active level and, therefore, do not include solvents and by-products that may be present in commercial materials, unless otherwise specified.

The pressurized antiperspirant compositions of the present invention can comprise, consist of, or consist essentially of the following components comprising the essential elements and limitations of the invention described herein, as well as any of the additional or optional ingredients, components, or limitations described herein or otherwise useful in pressurized antiperspirant applications.

Liquid polyols

The pressurized antiperspirant compositions of the present invention include liquid polyols selected to solubilize or aid in the solubilization of the antiperspirant active in the composition. The antiperspirant composition preferably comprises from about 1% to about 80% by weight of the selected liquid polyol, more preferably from about 2% to about 60%, even more preferably from about 3% to about 20%.

The liquid polyol used in the pressurized antiperspirant compositions of the present invention is selected to have at least 4 carbon atoms with adjacent hydroxyl-substituted carbon atoms in the alpha and beta positions of the liquid polyol. The liquid polyols preferably used in the present compositions correspond to the formula:

wherein R is an amide, ester, alkyl, ether or siloxane containing moiety, each moiety containing at least 2 carbon atoms. The R group is preferably an alkyl or ether group, more preferably an alkyl group containing from about 2 to about 10 carbon atoms, and still more preferably from about 4 to about 6 carbon atoms. The liquid polyol preferably contains a total of 2 or 3 hydroxyl groups.

Thus, the R group on the liquid polyol can be substituted or unsubstituted, branched, linear or cyclic, saturated or unsaturated. Non-limiting examples of suitable substituents include hydroxyl groups, amino groups, ester groups, ether groups, alkoxy groups (e.g., ethoxy, propoxy, etc.), and the like.

Non-limiting examples of suitable liquid polyols for use in the pressurized antiperspirant compositions of the present invention include: 1, 2-butanediol; 1, 2-pentanediol; 4-methyl-1, 2-pentanediol; 2-methyl-1, 2-pentanediol; 3, 3-methyl-1, 2-butanediol; 4-methyl-1, 2-hexanediol; 1, 2-heptanediol; 3-phenyl-1, 2-propanediol; 1, 2, 6-hexanetriol; 1, 2-hexanediol; 1, 2, 4-butanetriol; and mixtures thereof. Other suitable liquid polyols include: glycerol ethers, such as glycerol isopropyl ether; glyceryl propyl ether; glycerol ethyl ether; glyceryl methyl ether; glycerol butyl ether; glycerol isoamyl ether; diglycerol isopropyl ether; diglycerol isobutyl ether; diglycerin; triglycerol; triglycerol isopropyl ether; and mixtures thereof. Still other suitable liquid polyols include: glycerol acetate; glyceryl propionate; glycerol butyrate; 3-methylbutanoic acid glycerol ester; 3-trimethylsilyl-1, 2-propanediol; siloxane group-containing 1, 2-diols as described in U.S. patent 5,969,172 (Nye); and mixtures thereof.

These selected polyols are formulated into antiperspirant compositions alone or preferably in combination with one or more other anhydrous liquid carriers. Examples of such other anhydrous carriers include any known or effective liquid carrier suitable for topical application to the skin and which is compatible with the solubilized antiperspirant active, propellant portion of the composition.

The pressurized antiperspirant compositions of the present invention are preferably anhydrous, but typically will contain at least a small amount of moisture associated with the antiperspirant active during formulation. In this context, the term "anhydrous" means that the antiperspirant compositions of the present invention preferably comprise less than 10% moisture, more preferably less than 5%, even more preferably less than 3%, and most preferably less than 1% by weight of the composition.

Solubilized antiperspirant active

The pressurized antiperspirant compositions of the present invention comprise a solubilized antiperspirant active suitable for application to human skin. The concentration of antiperspirant active in the composition should be sufficient to provide the desired antiperspirant product with control of perspiration wetness and odor. The antiperspirant active is preferably partially solubilized by the liquid polyol as previously described.

The solubilized antiperspirant active concentration in the pressurized antiperspirant composition preferably ranges from about 0.1% to about 26%, more preferably from about 1% to about 20%, and even more preferably from about 2% to about 10% by weight of the composition. All such weight percentages are calculated on an anhydrous salt basis, excluding the weight of water and any complexing or buffering agents, such as glycine, glycine salts or other complexing or buffering agents.

Solubilized antiperspirant active for use in the pressurized antiperspirant compositions of the present invention include any compound, composition, or other material having antiperspirant activity. Preferred antiperspirant actives include astringent metallic salts, especially organic and inorganic salts of aluminum, zirconium, zinc, and mixtures thereof. Particularly preferred are salts such as: aluminum halides, aluminum chlorohydrate, aluminum hydroxyhalides, zirconyl oxyhalides, zirconyl hydroxyhalides, and mixtures thereof. Aluminum salts are most preferred for use in the non-contact pressurized composition.

Preferred aluminum salts for use in antiperspirant compositions correspond to the formula:

Al₂(OH)_aCl_b·xH₂O

wherein, a is from about 2 to about 5; the sum of a and b is about 6; x is from about 1 to about 6; where a, b, x may be non-integer values. Particularly preferred are the basic aluminum chlorides known as "5/6 basic chloride" (where a is 5) and "2/3 basic chloride" (where a is 4). The preparation of aluminum salts is disclosed in U.S. patent 3,887,692, (Gilman, published on 3.6.1975); U.S. patent 3,904,741 (jokes et al, published 9/9 1975); U.S. patent 4,359,456(Gosling et al, published on 16.11.1982), all of which are incorporated herein by reference. Aluminum salt mixtures are described in british patent specification 1,347,950(Shin et al, published on 2/27 of 1974).

The zirconium salts used in the antiperspirant compositions, especially pressurized contact dosage forms, conform to the formula:

ZrO(OH)_2-aCl_a·xH₂O

wherein a is any number between 0 and about 2; x is from about 1 to about 7; where a and x may both be non-integer values. Preferred zirconium salts are mixtures additionally containing aluminium or glycine, commonly known as ZAG. These ZAG mixtures contain aluminum chlorohydrate and zirconyl chlorohydrate corresponding to the general formulas described above. Such ZAG mixtures are described in U.S. Pat. No. 3,679,068 (Lueders et al, published 1974, 12.2 months); british patent application 2,144,992(callaghan et al, published on 20/3/1985); U.S. Pat. No. 4,120,948(Shelton, published on 17/10 1978).

Preferred antiperspirant actives for use in the compositions include: aluminum chlorohydrate, tetrahydroxy-dialuminum chlorohydrate, 4.5 hydroxy-dialuminum sesquichloride hydrate, a complex of basic aluminum chloride and propylene glycol, a complex of tetrahydroxy-dialuminum dichlorohydrate and propylene glycol, a complex of 4.5 hydroxy-dialuminum sesquichloride hydrate and propylene glycol, a complex of basic aluminum chloride and polyethylene glycol, a complex of tetrahydroxy-dialuminum dichlorohydrate and polyethylene glycol, a complex of 4.5 hydroxy-dialuminum sesquichloride hydrate and polyethylene glycol, buffered aluminum sulfate, and mixtures thereof.

Non-limiting examples of solubilized antiperspirant actives for use in the pressurized antiperspirant compositions of the present invention, and methods of making the solubilized actives, are described in U.S. patent 6,149,897 (Swaile); us patent 6,126,928 (Swalle); U.S. Pat. No. 5,968,489(Swaile et al), the description of which is incorporated herein by reference. Other non-limiting examples of solubilized antiperspirant actives and methods of making the same are described in european patent EP 0404533 (Smith et al).

Propellant

The pressurized antiperspirant compositions of the present invention comprise a dimethyl ether propellant in combination with a low polarity solvent as described later herein, wherein the weight ratio of dimethyl ether to the low polarity solvent is from about 0.1 to about 2.8, preferably from about 0.2 to about 1.0, more preferably from about 0.2 to about 0.5.

The propellant portion of the pressurized antiperspirant compositions of the present invention may comprise dimethyl ether alone or in combination with any other known or suitable propellant suitable for application to the skin, preferably in combination with a hydrocarbon propellant. The concentration of dimethyl ether or total propellant in the pressurized antiperspirant compositions of the present invention is from about 5% to about 99%, more typically from about 15% to about 90%, and even more preferably from about 30% to about 70% by weight of the composition. The total amount of dimethyl ether and hydrocarbon propellant is preferably from about 50% to 100%, more preferably 100%, by weight of the total propellant. Although not preferred, minor amounts of other propellants, such as nitrous oxide, carbon dioxide, and halogenated hydrocarbons, such as trichloromonofluoromethane, dichlorodifluoromethane, dichlorotetrafluoroethane, trichlorotrifluoroethane, Trichlorotetrafluoroethane (trichlorofluoroethane), monochlorodifluoromethane, and mixtures thereof, may be included in the composition.

Suitable hydrocarbon propellants for use in the pressurized antiperspirant compositions include any known or otherwise suitable hydrocarbon propellant for application to human skin, non-limiting examples of which include propane, butane, pentane, isobutane, and mixtures thereof. These hydrocarbon propellants are typically formulated into the antiperspirant compositions in the form of liquefied gases, and are characterized by the fact that the compositions of the present invention are defined as low polarity solvents having a solubility parameter of less than about 8.0, which low polarity solvents are described in more detail later herein.

Low polarity solvent

The pressurized antiperspirant compositions of the present invention comprise a low polarity solvent in combination with a dimethyl ether propellant as described above, wherein the weight ratio of dimethyl ether propellant to low polarity solvent is selected within the above ranges as defined in this patent. The low polarity solvent may be any material that is liquid at ambient conditions or that is present in a liquid state in the pressurized composition as described in this patent, and has a solubility parameter of less than about 8.0, preferably from about 1 to about 6, more preferably from about 1 to about 4.

The low polarity solvent used in the compositions of the present invention is preferably a liquefied hydrocarbon propellant, non-limiting examples of which include propane, butane, isopentane, pentane, isobutane, and mixtures thereof. In this context, the liquefied hydrocarbon propellant acts as both a low polarity solvent and an additional propellant in the pressurized composition. The hydrocarbon propellant, which is a low polarity solvent, is preferably formulated in combination with a dimethyl ether propellant, wherein the weight ratio of dimethyl ether to hydrocarbon propellant in this preferred embodiment is from about 0.1 to 2.0, more preferably from about 0.1 to 1.0, even more preferably from about 0.2 to about 0.8.

Other low polarity solvents that may be used in the pressurized antiperspirant compositions of the present invention include any silicone or silicone-containing material known or suitable for topical application to the skin, provided that the silicone or silicone-containing material is liquid at ambient conditions, or is present in the pressurized antiperspirant compositions of the present invention in liquid form, provided that the silicone or silicone-containing material has the solubility parameters as claimed herein. The silicone or silicone-containing materials used as low polarity solvents in the pressurized antiperspirant compositions of the present invention can be volatile or nonvolatile, cyclic, linear or branched, substituted or unsubstituted.

The silicone liquid is preferably present in the composition as a low polarity solvent at a concentration of from about 0.1% to about 50%, more preferably from about 1% to about 25%, and still more preferably from about 2% to about 15%, by weight of the pressurized antiperspirant composition.

Non-limiting examples of suitable volatile silicones are described in the document "Todd et al, 'volatile silicone liquids for cosmetic use', cosmetics and toiletries, 91: 27-32(1976) "[ Todd et al", "Voice silicon Fluids for Cosmetics", Cosmetics and Toiletries, 91: 27-32(1976) ], the description of which is incorporated herein by reference. Among these volatile silicones, cyclic silicones containing from about 3 to about 7 silicon atoms are preferred, and from about 4 to about 5 silicon atoms are more preferred. The most preferred siloxanes correspond to the formula:

wherein n is from about 3 to about 7, preferably from about 4 to about 5, and most preferably 5. These volatile cyclic siloxanes generally have viscosity values of less than about 10 centistokes, measured at 25 ℃. Volatile silicones suitable for use in this patent include, but are not limited to, Cyclomethicone D-5 (available from G.E. Silicones corporation); DC 1184, dow-corning 344, dow-corning 345 (available from dow-corning corporation); GE 7207, GE7158, and silicone fluids SF-1202, SF-1173 (available from general electric); SWS-03314, SWS-03400, F-222, F-223, F-250, F-251 (available from SWSSilicones corporation); volatile silicones 7158, 7207, 7349 (available from Union carbide); masil SF-V (available from Mazer); and mixtures thereof. Among the volatile cyclic siloxanes, cyclopentasiloxane is most preferred.

Non-volatile silicones useful in the pressurized antiperspirant compositions of the present invention, non-limiting examples of which correspond to either of the following two general formulas:

or

Wherein n is greater than or equal to 1. These linear silicone materials typically have viscosity values of from about 10 centistokes to about 100,000 centistokes, preferably less than about 500 centistokes, more preferably from about 20 centistokes to about 200 centistokes, even more preferably from about 20 centistokes to about 50 centistokes, under ambient conditions. Non-limiting examples of non-volatile linear silicones suitable for use in the antiperspirant composition include, but are not limited to Dow-Corning 200, hexamethyldisiloxane (hexamethyldisiloxane), Rhodorsil oil 70047 (available from Rhone-Poulenc), Masil SF fluid (available from Mazer), Dow-Corning 225, Dow-Corning 1732, Dow-Corning 5732, Dow-Corning 5750 (available from Dow-Corning), SF-96, SF-1066and SF18(350) silicone fluid (available from G.E. Silicones); velvasil and Viscasil (available from general electric company); siloxane L-45, siloxane L530, siloxane L-531 (available from Union carbide), siloxane F-221, and siloxane fluid SWS-101 (available from SWS Silicones).

Other silicone liquids useful as low polarity solvents in the pressurized antiperspirant compositions of the present invention include modified or organofunctionalized silicone carriers such as polyalkyl siloxanes, polyalkylaryl siloxanes, crosslinked silicone elastomers, polyester siloxanes, polyether siloxane block copolymers, polyfluorinated siloxanes, polyaminosiloxanes, and mixtures thereof. These modified silicone carriers are typically liquid at ambient conditions and preferably have a viscosity of less than about 100,000 centistokes, more preferably less than about 500 centistokes, even more preferably from about 1 centistoke to about 50 centistokes, most preferably from about 1 centistoke to about 20 centistokes. Such modified silicone carriers are generally well known in the chemical arts, some examples of which are described in "1 cosmetic, scientific and technical, 27-104(m.balsam, ed. sagaring. 1972), [1 Cosmetics, Science and Technology 27-104(m.balsam and e.sagaring. 1972) ]; U.S. Pat. No. 4,202,879 (Shelton, 13.5.1980); U.S. Pat. No. 5,069,897 (issued to Orr, 3.12.1991); the description of which is incorporated herein by reference.

The pressurized antiperspirant compositions of the present invention may also comprise a wide variety of other materials for use as the low polarity solvent, provided that such other materials have the solubility parameters defined herein and that the weight ratio of dimethyl ether to the low polarity solvent when formulated into the composition is within the ranges set forth herein. Such other materials include volatile and non-volatile hydrocarbons other than the hydrocarbon propellants described above in the present invention.

Optional ingredients

The pressurized antiperspirant compositions of the present invention may also include other optional components which modify the physical, chemical, cosmetic or aesthetic characteristics of the composition and may also be deposited on the skin as additional active components. The composition may also further comprise optional inert ingredients. Many such optional ingredients are well known for use in deodorants, antiperspirants or other personal care compositions, and may be used in the antiperspirant compositions of the present invention, provided that such optional materials are compatible with the essential materials described herein or do not unduly impair product performance.

Non-limiting examples of optional ingredients include preservatives, deodorizing antimicrobials, fragrances, deodorizing fragrances, dyes or pigments, thickeners, pH adjusting agents, surfactants and other elution aids, cosolvents, emollients or residue masking liquids other than the silicone fluids described herein, pharmaceutically active ingredients, vitamins, and mixtures thereof. Preferred optional ingredients include dimethicone copolyols.

Although the pressurized antiperspirant composition may further comprise any organic or silicone-containing liquid carrier other than the selected polyhydric alcohols and silicone liquids described herein, the composition is preferably substantially free of ethanol, and is also preferably substantially free of propylene glycol or dipropylene glycol. In this context, the term "substantially free" means that the pressurized antiperspirant composition is preferably less than 5%, more preferably less than 3%, even more preferably less than 1%, and most preferably zero by weight of any of the above materials alone.

Product dosage form

The pressurized antiperspirant compositions of the present invention are preferably anhydrous formulations. Although not limited to clear or single phase systems, clear or single phase liquids are also preferred for the present invention. These pressurized antiperspirant compositions are packaged in any known or suitable pressurized container for delivery of any selected pressurized formulation of the combination of materials described herein. The pressurized antiperspirant compositions are also preferably free of any suspended or dispersed solids, e.g., solids concentrations insufficient to significantly reduce the clarity of the composition.

The pressurized antiperspirant compositions can be packaged in conventional pressurized containers for contact and non-contact dosage forms. Non-contact product form pressure vessels are well known in the antiperspirant and personal care arts, non-limiting examples of which are described in U.S. patent 3,082,917; us patent 3,083,918; us patent 3,544,258; the description of which is incorporated herein by reference. Pressurized contact antiperspirants are also well known in the antiperspirant art, and non-limiting examples are described in U.S. patent 5,567,073(de Laforcade et al), the description of which is incorporated herein by reference.

The term "contact" or "contact product form" refers to any known or suitable pressurized package comprising an applicator wherein the antiperspirant composition is delivered under pressure to the surface of the applicator, thereby applying the antiperspirant composition directly to the underarm area of the skin. In this context, during application, the surface of the applicator is in direct contact with the underarm skin, thereby delivering or depositing the antiperspirant composition to the skin at the underarm site.

The term "non-contact" or "non-contact product form" as used herein means that the antiperspirant composition is applied to the underarm pressurized package by a product stream that is generated under pressure within the package and applied to the skin. In this context, any surface of the pressurized pack is not in direct contact with the underarm skin.

Manufacturing method

The pressurized antiperspirant compositions of the present invention can be prepared by any known or effective process suitable for making or formulating a clear or single-phase pressurized antiperspirant formulation. These pressurized compositions are generally prepared by adding all of the ingredients, except dimethyl ether and other selected propellants, either separately or pre-mixed, to a suitable container. The container is then sealed and the residual air in the container is evacuated. The propellant is then added to the sealed container in the form of a liquefied gas under suitable pressure. Preferred compositions and methods of making the same are described in later embodiments of the pressurized antiperspirant compositions of the present invention.

It has been found that when the dimethyl ether propellant is used in combination with a hydrocarbon or other similar propellant, it is preferred to add the dimethyl ether to the composition after the hydrocarbon or other similar propellant has been added to the composition. This particular manufacturing process has been found to help stabilize the composition during formulation, thereby reducing or eliminating any active settling during manufacture. This particular manufacturing process is also preferably applied to the pressurized antiperspirant compositions of the present invention, and can be applied to any pressurized antiperspirant composition known or disclosed in the antiperspirant art that contains a solubilized antiperspirant active in combination with dimethyl ether and other propellants such as hydrocarbon liquefied gases.

Examples

The following examples further describe and demonstrate particular embodiments within the scope of the present invention. These examples are for illustrative purposes only and should not be construed as limiting the invention. Many modifications may be made without departing from the spirit or scope of the invention. All amounts in the examples are concentrations based on the total weight of the composition, unless otherwise specified.

The compositions of examples A-P below are all anhydrous pressurized antiperspirant compositions that are single phase systems having a clear or translucent appearance. Each composition is packaged in a pressurized contact container or a pressurized non-contact spray container. The product is applied to the underarm area of the skin to achieve antiperspirant and deodorant effects. The product results in little or no visible residue during or after application to the underarm.

The compositions described below (examples a-P) were formulated by combining or mixing the ingredients listed for each composition in the liquid state at ambient conditions in a glass bottle (suitable for pressurized packaging operations). The vial was then sealed with a transfer valve and evacuated to a pressure of 14 to 25 inches (36 to 64 cm) of mercury. The propellant in each formulation was then added to the glass bottle under the appropriate pressure using a burette inflator. If the formulation contains more than one propellant material, the dimethyl ether is always added last. The encapsulated composition was heated in a water bath (65 ℃, 150 ° F) for 5 minutes to confirm proper encapsulation of the valve. Each of the resulting compositions is a clear or single-phase pressurized antiperspirant composition that remains stable for extended periods of time under ambient storage conditions without the use of ethanol or water as a solvent.

Each of the compositions described below (examples A-P) was formulated using a solubilized antiperspirant active solution. The solution is prepared by co-spray drying an initial solution of antiperspirant active with a moderately polar solvent to form a spray-dried active powder, and then dissolving the spray-dried active powder in the selected 1, 2-diol solvent with simple agitation, without the need for heating, to form an antiperspirant active solution for formulation into the pressurized antiperspirant compositions of the examples of this patent. More particularly, the preparation of solubilized antiperspirant active for use in formulating the pressurized antiperspirant compositions described in the examples of this patent. The active substance is prepared by preparing 40% by weight of aluminum chlorohydrate or aluminum zirconium chlorohydrate glycine complex, 9% by weight of butanediol and 2% by weight of polyethylene glycol 1000 into a liquid mixture. The resulting liquid mixture is spray dried to provide a spray dried powder containing about 65% to 75% by weight antiperspirant active and 20% by weight of a moderately polar solvent (the solubility parameter of the moderately polar solvent being from about 9 to about 15). At ambient conditions, about 30 parts of the resulting spray-dried powder was mixed with 70 parts of 1, 2-diol with simple stirring, without heating, for about two hours to form the final antiperspirant active solution for formulating the pressurized antiperspirant compositions of the examples described in this patent.

Table 1: anhydrous pressurized antiperspirant products

Composition (I)	A	B	C	D	E	F	G	H
									Dimethyl ether	20	15	20	20	10	20	20	40
Butane	60	45		25	40	60	60
									Pentane (pentane)			60
Isobutane				30
									Propane				3
15% aluminum chlorohydrate 1, 2-hexanediol solution	12			10		4
									25% aluminum chlorohydrate glycerol isopropyl ether solution		25
20% aluminum chlorohydrate glycerol butyl ether solution			10		25
									25% aluminum chlorohydrate 1, 2-pentanediol solution							13	20
Dimethylsiloxane (10cst)	7	14		3		5		10
									Dimethicone copolyol			4	3	10		6	5
Cyclic pentylsiloxane			5	3	14	10		25
									Perfume	1	1	1	1	1	1	1
Weight ratio of dimethyl ether to low polar solvent	0.29	0.30	0.28	0.30	0.19	0.27	0.30	1.14

Table 2: anhydrous pressurized antiperspirant compositions

Composition (I)	I	J	K	L	M	N	O	P
									Dimethyl ether	30	15	20	20	50	40	30	20
Butane			19					20
									Isohexadecane						25
Mineral oil							30
									20% aluminum chlorohydrate 1, 2-hexanediol solution	30			20		25	20	30
25% aluminum chlorohydrate glycerol isopropyl ether solution		25
									25% aluminum chlorohydrate glycerol butyl ether solution			20		25
Dimethylsiloxane (10cst)		14	20	10				10
									Dimethicone copolyol					10			10
Cyclic pentylsiloxane	39		20	49	14	9	9	10
									Hexamethyldisiloxane		45
Perfume	1	1	1	1	1	1	1
									Weight ratio of dimethyl ether to low polar solvent	0.76	0.25	0.28	0.33	2.6	1.2	1.4	0.4

Claims (10)

1. A pressurized antiperspirant composition, the composition characterized by:

(a) a polyol solvent having at least 4 carbon atoms and containing hydroxyl groups on each of the alpha and beta carbon atoms of the polyol solvent;

(b) a solubilized antiperspirant active;

(c) dimethyl ether; and

(d) a low polarity solvent having a solubility parameter less than 8.0;

wherein the weight ratio of the dimethyl ether to the low polarity solvent is 0.1 to 2.8.

2. The composition of claim 1, wherein the low polarity solvent is a hydrocarbon propellant.

3. The composition of claim 2 wherein the weight ratio of dimethyl ether to hydrocarbon propellant is from 0.1 to 2.0.

4. The composition of claim 1, wherein the low polarity solvent is a silicone liquid.

5. The composition of claim 4, wherein the silicone fluid is from 0.1% to 50% by weight of the composition.

6. The composition of claim 1, wherein the composition is anhydrous and comprises less than 10% water by weight.

7. The composition of claim 1, wherein the composition is anhydrous and comprises less than 1% water by weight.

8. The composition of claim 1, wherein the composition is a single phase system.

9. The composition of claim 1, wherein the low polarity solvent has a solubility parameter of 1 to 4.

10. The composition of claim 1 wherein the weight ratio of dimethyl ether to low polarity solvent is from 0.2 to 1.0.