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Publication of GT201500189ApublicationCriticalpatent/GT201500189A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
LA PRESENTE INVENCIÓN SE REFIERE A NUEVOS COMPUESTOS DE FÓRMULA (I) (I) QUE SE AUTOTAXINA INHIBIDORES, PROCEDIMIENTOS PARA SU PREPARACIÓN, COMPOSICIONES FARMACÉUTICAS Y MEDICAMENTOS QUE LOS CONTIENEN Y A SU USO EN EL TRATAMIENTO DE UNA ENFERMEDAD O CONDICIÓN ATX-DEPENDIENTE O MEDIADA POR ATX .THE PRESENT INVENTION REFERS TO NEW FORMULA COMPOUNDS (I) (I) THAT AUTOTAXINES INHIBITORS, PROCEDURES FOR THE PREPARATION, PHARMACEUTICAL COMPOSITIONS AND MEDICINES CONTAINING THEM AND THEIR USE IN THE TREATMENT OF A DISEASE OR CONDITION ATX
Compounds derived from 2-oxo-piperidine and 1,1-dioxide-thiazine, mdm2 inhibitors; pharmaceutical composition that includes them; and its use for the treatment of cancer.
DERIVATIVES OF ESTRA-1,3,5 (10), 16-TETRAEN-3-CARBOXAMIDE, PROCEDURES FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS THAT CONTAIN THEM, AS WELL AS THEIR USE FOR THE PREPARATION OF MEDICINES
DERIVATIVES OF ESTRA 1,3,5 (10), 16 TETRAENE 3 SUBSTITUTES, METHODS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THEM, AS WELL AS THEIR USE FOR THE PREPARATION OF MEDICINES
Piperazine derived compounds; pharmaceutical composition; comprising one of the compounds and use of the compounds in the preparation of medicaments for the treatment and / or prevention of protozoal infections, in particular for the treatment and / or prevention of malaria.