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GT201300153A - Formas cristalinas de 5-cloro-n2-(2-isopropoxi-5-metil-4-piperidin-4-il-fenil)- n4-[2-(propan-2-sulfonil)-fenil pirimidim-2,4-diamina - Google Patents

Formas cristalinas de 5-cloro-n2-(2-isopropoxi-5-metil-4-piperidin-4-il-fenil)- n4-[2-(propan-2-sulfonil)-fenil pirimidim-2,4-diamina

Info

Publication number
GT201300153A
GT201300153A GT201300153A GT201300153A GT201300153A GT 201300153 A GT201300153 A GT 201300153A GT 201300153 A GT201300153 A GT 201300153A GT 201300153 A GT201300153 A GT 201300153A GT 201300153 A GT201300153 A GT 201300153A
Authority
GT
Guatemala
Prior art keywords
penim
isopropoxi
pyrimidim
propan
piperidin
Prior art date
Application number
GT201300153A
Other languages
English (en)
Inventor
Feng Lili
Gong Baoqing
Piotr H Karpinski
Waykole Liladhar Murlidhar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45464892&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GT201300153(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of GT201300153A publication Critical patent/GT201300153A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

SE DESCRIBEN SUSTANCIAS 5-CLORO-N2-(2-ISOPROPOXI-5-METIL-4-PIPERIDIN-4-IL-FENIL)-N4-[2-(PROPAN-2-SULFONIL)-FENIL PIRIMIDIM-2,4-DIAMINA A LOS MÉTODOS PARA LA ELABORACIÓN DE LAS MISMAS, A COMPOSICIONES FARMACÉUTICAS QUE COMPRENDEN LAS MISMAS
GT201300153A 2010-12-17 2013-06-17 Formas cristalinas de 5-cloro-n2-(2-isopropoxi-5-metil-4-piperidin-4-il-fenil)- n4-[2-(propan-2-sulfonil)-fenil pirimidim-2,4-diamina GT201300153A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201061424194P 2010-12-17 2010-12-17

Publications (1)

Publication Number Publication Date
GT201300153A true GT201300153A (es) 2014-06-09

Family

ID=45464892

Family Applications (1)

Application Number Title Priority Date Filing Date
GT201300153A GT201300153A (es) 2010-12-17 2013-06-17 Formas cristalinas de 5-cloro-n2-(2-isopropoxi-5-metil-4-piperidin-4-il-fenil)- n4-[2-(propan-2-sulfonil)-fenil pirimidim-2,4-diamina

Country Status (36)

Country Link
US (2) US9309229B2 (es)
EP (3) EP2651918B1 (es)
JP (1) JP5916752B2 (es)
KR (4) KR20130130022A (es)
CN (7) CN112125884A (es)
AR (2) AR084309A1 (es)
AU (1) AU2011343775B2 (es)
BR (1) BR112013015000A2 (es)
CA (1) CA2821102C (es)
CL (1) CL2013001723A1 (es)
CO (1) CO6801792A2 (es)
CY (2) CY1119474T1 (es)
DK (2) DK3121171T3 (es)
EC (1) ECSP13012770A (es)
ES (3) ES2643016T3 (es)
GT (1) GT201300153A (es)
HR (2) HRP20171477T1 (es)
HU (1) HUE041845T2 (es)
IL (1) IL226474A (es)
LT (2) LT2651918T (es)
MA (1) MA34771B1 (es)
MX (1) MX338210B (es)
MY (2) MY164810A (es)
NZ (1) NZ610713A (es)
PE (1) PE20140698A1 (es)
PH (1) PH12013501254A1 (es)
PL (2) PL2651918T3 (es)
PT (2) PT2651918T (es)
RS (1) RS57771B1 (es)
RU (2) RU2746159C2 (es)
SG (2) SG10201510082XA (es)
SI (2) SI2651918T1 (es)
TN (1) TN2013000216A1 (es)
TW (2) TWI576344B (es)
WO (1) WO2012082972A1 (es)
ZA (1) ZA201303599B (es)

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CN105272921A (zh) * 2014-06-09 2016-01-27 江苏奥赛康药业股份有限公司 一种制备Ceritinib的方法及其中间体化合物
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CN111888368B (zh) 2014-10-21 2024-02-02 武田药品工业株式会社 5-氯-n4-[2-(二甲基磷酰基)苯基]-n2-{2-甲氧基-4-[4-(4-甲基哌嗪-1-基)哌啶-1-基]苯基}嘧啶-2,4-二胺的晶形
WO2016081538A1 (en) 2014-11-18 2016-05-26 Teva Pharmaceuticals International Gmbh Solid state forms of ceritinib and salts thereof
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CN106699743B (zh) 2015-11-05 2020-06-12 湖北生物医药产业技术研究院有限公司 嘧啶类衍生物及其用途
WO2017152858A1 (zh) * 2016-03-11 2017-09-14 苏州晶云药物科技有限公司 色瑞替尼的晶型及其制备方法
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JP2019196359A (ja) * 2019-06-17 2019-11-14 ノバルティス アーゲー ピリミジン誘導体およびそれらの中間体を調製する化学的方法
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CN105061397B (zh) 2015-08-07 2018-01-02 武汉英普瑞医药科技有限公司 一种色瑞替尼的c型晶型及其制备方法与应用

Also Published As

Publication number Publication date
IL226474A (en) 2016-03-31
TWI576344B (zh) 2017-04-01
WO2012082972A1 (en) 2012-06-21
LT2651918T (lt) 2017-10-10
PT2651918T (pt) 2017-10-17
RU2599785C2 (ru) 2016-10-20
ZA201303599B (en) 2014-02-26
US20130274279A1 (en) 2013-10-17
CN107056751A (zh) 2017-08-18
EP3121171A1 (en) 2017-01-25
SG190856A1 (en) 2013-07-31
PH12013501254A1 (en) 2016-07-29
PE20140698A1 (es) 2014-06-11
RU2016136823A (ru) 2018-12-11
CN106831716A (zh) 2017-06-13
US20160175305A1 (en) 2016-06-23
TW201307299A (zh) 2013-02-16
HUE041845T2 (hu) 2019-05-28
PT3121171T (pt) 2018-11-27
HRP20181737T1 (hr) 2018-12-28
AR084309A1 (es) 2013-05-08
SG10201510082XA (en) 2016-01-28
KR20180032680A (ko) 2018-03-30
DK3121171T3 (en) 2018-12-10
CN106008462A (zh) 2016-10-12
IL226474A0 (en) 2013-07-31
ECSP13012770A (es) 2013-10-31
CY1121017T1 (el) 2019-12-11
RU2599785C3 (ru) 2019-04-24
PL2651918T3 (pl) 2017-12-29
LT3121171T (lt) 2018-11-12
CO6801792A2 (es) 2013-11-29
CN112125884A (zh) 2020-12-25
TW201629021A (zh) 2016-08-16
KR20130130022A (ko) 2013-11-29
RU2016136823A3 (es) 2020-02-06
KR20190022903A (ko) 2019-03-06
CN103282359A (zh) 2013-09-04
MX2013006952A (es) 2013-07-15
EP2651918A1 (en) 2013-10-23
CA2821102C (en) 2019-06-11
JP2013545812A (ja) 2013-12-26
RS57771B1 (sr) 2018-12-31
EP3453708A1 (en) 2019-03-13
AU2011343775A1 (en) 2013-07-18
HRP20171477T1 (hr) 2017-11-17
ES2905973T3 (es) 2022-04-12
DK2651918T3 (en) 2017-10-23
AR122395A2 (es) 2022-09-07
MY164810A (en) 2018-01-30
EP3453708B8 (en) 2022-03-16
ES2696526T3 (es) 2019-01-16
CN114989139A (zh) 2022-09-02
RU2746159C2 (ru) 2021-04-08
CY1119474T1 (el) 2018-04-04
TN2013000216A1 (en) 2014-11-10
RU2013132947A (ru) 2015-01-27
PL3121171T3 (pl) 2019-01-31
MX338210B (es) 2016-04-07
EP3121171B1 (en) 2018-08-15
EP2651918B1 (en) 2017-07-12
CA2821102A1 (en) 2012-06-21
AU2011343775B2 (en) 2015-12-03
TWI576343B (zh) 2017-04-01
MY177742A (en) 2020-09-23
KR102325775B1 (ko) 2021-11-12
KR20200039021A (ko) 2020-04-14
EP3453708B1 (en) 2021-10-27
NZ610713A (en) 2014-10-31
CL2013001723A1 (es) 2013-12-27
MA34771B1 (fr) 2013-12-03
US9309229B2 (en) 2016-04-12
JP5916752B2 (ja) 2016-05-11
SI2651918T1 (sl) 2017-10-30
SI3121171T1 (sl) 2018-11-30
CN104262324A (zh) 2015-01-07
ES2643016T3 (es) 2017-11-21
BR112013015000A2 (pt) 2016-08-09

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