[go: up one dir, main page]

GT200300285A - Nuevos enantiomeros (r) y (s) de derivados del acido tiofeno hidroxamico - Google Patents

Nuevos enantiomeros (r) y (s) de derivados del acido tiofeno hidroxamico

Info

Publication number
GT200300285A
GT200300285A GT200300285A GT200300285A GT200300285A GT 200300285 A GT200300285 A GT 200300285A GT 200300285 A GT200300285 A GT 200300285A GT 200300285 A GT200300285 A GT 200300285A GT 200300285 A GT200300285 A GT 200300285A
Authority
GT
Guatemala
Prior art keywords
hydroxamic
acid derivatives
thiophen
enantiomers
new
Prior art date
Application number
GT200300285A
Other languages
English (en)
Inventor
Adelbert Grossmann
Frank Herting
Matthias Koerner
Klaus-Peter Kuenkele
Anja Limberg
Olaf Mundigl
Ulrich Tibes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200300285A publication Critical patent/GT200300285A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A COMPUESTOS DE LA FORMULA GENERAL I EN LA QUE AR,R1,R2, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS SON INHIBIDORES DE LA DESACETILASA HISTONA (HDAC) POR LO QUE SON DE UTILIDAD EN CUADROS DE HIPERPROLIFERACION CELULAR TALES COMO EL CANCER.
GT200300285A 2002-12-16 2003-12-12 Nuevos enantiomeros (r) y (s) de derivados del acido tiofeno hidroxamico GT200300285A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02028038 2002-12-16

Publications (1)

Publication Number Publication Date
GT200300285A true GT200300285A (es) 2004-07-14

Family

ID=32524005

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200300285A GT200300285A (es) 2002-12-16 2003-12-12 Nuevos enantiomeros (r) y (s) de derivados del acido tiofeno hidroxamico

Country Status (18)

Country Link
US (1) US7098241B2 (es)
EP (1) EP1575933A1 (es)
JP (1) JP2006513181A (es)
KR (1) KR100781929B1 (es)
CN (1) CN100391954C (es)
AR (1) AR042459A1 (es)
AU (1) AU2003293882A1 (es)
BR (1) BR0317348A (es)
CA (1) CA2507629A1 (es)
CL (1) CL2003002611A1 (es)
GT (1) GT200300285A (es)
PA (1) PA8592101A1 (es)
PE (1) PE20040913A1 (es)
PL (1) PL377696A1 (es)
RU (1) RU2348625C2 (es)
TW (1) TW200418825A (es)
UY (1) UY28127A1 (es)
WO (1) WO2004054999A1 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP1753A (en) * 2001-06-11 2007-07-18 Shire Biochem Inc Thiophene derivatives as antiviral agents for flavvivirus infection
US7154002B1 (en) 2002-10-08 2006-12-26 Takeda San Diego, Inc. Histone deacetylase inhibitors
US7250514B1 (en) 2002-10-21 2007-07-31 Takeda San Diego, Inc. Histone deacetylase inhibitors
CN100413861C (zh) 2002-12-10 2008-08-27 维勒凯姆制药股份有限公司 用于治疗或预防黄病毒感染的化合物
US7169801B2 (en) 2003-03-17 2007-01-30 Takeda San Diego, Inc. Histone deacetylase inhibitors
US20050261347A1 (en) * 2003-10-24 2005-11-24 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
US7435837B2 (en) * 2003-10-24 2008-10-14 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
JP2008501665A (ja) * 2004-06-14 2008-01-24 エフ．ホフマン−ラ　ロシュ　アーゲー チオフェンヒドロキサム酸誘導体及びｈｄａｃ阻害剤としてのこれらの使用
CA2566512A1 (en) * 2004-06-14 2005-12-22 F. Hoffmann-La Roche Ag Hydroxamates, their manufacture and use as pharmaceutical agents
US7396944B2 (en) * 2004-06-14 2008-07-08 Hoffmann-La Roche Inc. Thiophene derivatives, their manufacture and use as pharmaceutical agents
WO2006066133A2 (en) 2004-12-16 2006-06-22 Takeda San Diego, Inc. Histone deacetylase inhibitors
US7642253B2 (en) 2005-05-11 2010-01-05 Takeda San Diego, Inc. Histone deacetylase inhibitors
ES2415742T3 (es) * 2005-05-13 2013-07-26 Vertex Pharmaceuticals (Canada) Incorporated Compuestos y procedimientos para el tratamiento o prevención de infecciones por flavivirus
WO2007011626A2 (en) 2005-07-14 2007-01-25 Takeda San Diego, Inc. Histone deacetylase inhibitors
GB0518237D0 (en) * 2005-09-07 2005-10-19 Angeletti P Ist Richerche Bio Therapeutic compounds
GB0522130D0 (en) * 2005-10-31 2005-12-07 Angeletti P Ist Richerche Bio Therapeutic compounds
GB0603041D0 (en) * 2006-02-15 2006-03-29 Angeletti P Ist Richerche Bio Therapeutic compounds
AP2579A (en) 2006-11-15 2013-01-29 Virochem Pharma Inc Thiophene analogues for the treatment or prevention of flavivirus infections
AR074797A1 (es) 2008-10-10 2011-02-16 Japan Tobacco Inc Compuesto de fluoreno , composiciones farmaceuticas , inhibidores de pdhk y pdhk2 , metodos de tratamiento , usos de los mismos y kit comercial
WO2011106627A1 (en) * 2010-02-26 2011-09-01 Millennium Pharmaceuticals, Inc. Substituted hydroxamic acids and uses thereof
US20110212969A1 (en) * 2010-02-26 2011-09-01 Millennium Pharmaceuticals, Inc. Substituted hydroxamic acids and uses thereof
WO2012019772A1 (en) * 2010-08-12 2012-02-16 Institut De Recherche Pour Le Developpement (I.R.D) Method for treating protozoan parasitic diseases
WO2012112447A2 (en) * 2011-02-14 2012-08-23 Dana-Farber Cancer Institute, Inc. Histone deacetylase inhibitors and methods of use thereof
US9499479B2 (en) 2011-10-03 2016-11-22 The Trustees Of Columbia University In The City Of New York Molecules that selectively inhibit histone deacetylase 6 relative to histone deacetylase 1
PL2975028T3 (pl) 2013-03-15 2018-10-31 Japan Tobacco, Inc. Związek pirazoloamidowy i jego zastosowania medyczne
CN103159646B (zh) * 2013-03-19 2014-10-22 广东药学院 一种异羟肟酸类化合物及其制备方法和应用
CA2933907A1 (en) 2013-12-23 2015-07-02 The Trustees Of Columbia University In The City Of New York Selective hdac6 inhibitors
TWI773657B (zh) 2015-12-18 2022-08-11 美商亞德利克斯公司 作爲非全身ｔｇｒ５促效劑之經取代之4-苯基吡啶化合物
US12084472B2 (en) 2015-12-18 2024-09-10 Ardelyx, Inc. Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists
CN109476609B (zh) 2016-07-29 2022-06-14 日本烟草产业株式会社 吡唑-酰胺化合物的制造方法
CN116120300B (zh) * 2023-02-21 2024-10-15 贵州大学 一种含异羟肟酸片段的嘧啶类化合物其制备方法和应用

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE661226A (fr) 1965-03-17 1965-09-17 Acides arylacethydroxamiques, amides correspondants et procedes de preparation.
NL6406688A (es) * 1964-06-05 1965-12-06
GB1200886A (en) * 1966-09-23 1970-08-05 Allen & Hanburys Ltd Phenylaminoethanol derivatives
US4173652A (en) * 1976-12-18 1979-11-06 Akzona Incorporated Pharmaceutical hydroxamic acid compositions and uses thereof
NL7614113A (nl) 1976-12-18 1978-06-20 Akzo Nv Hydroxamzuren.
JPS5436229A (en) 1977-08-25 1979-03-16 Hokuriku Pharmaceutical Substituted acetohydroxam derivative
JPS57145838A (en) 1981-03-05 1982-09-09 Hodogaya Chem Co Ltd P-benzyloxybenzoic acid derivative and herbicide containing the same
JPS57149254A (en) 1981-03-10 1982-09-14 Hodogaya Chem Co Ltd M-benzyloxybenzamide derivative and herbicide containing the same
GB8320702D0 (en) 1983-08-01 1983-09-01 Wellcome Found Chemotherapeutic agents
US4769461A (en) * 1986-09-16 1988-09-06 American Home Products Corporation Quinolinyl benzene hydroxamic acids as anti-inflammatory/antiallergic agents
GB8728051D0 (en) 1987-12-01 1988-01-06 Leo Pharm Prod Ltd Chemical compounds
JPH01216961A (ja) 1988-02-25 1989-08-30 Takeda Chem Ind Ltd １２−リポキシゲネース阻害剤
DE3903989A1 (de) * 1989-02-10 1990-09-20 Basf Ag Diphenylheteroalkylderivate, ihre herstellung und daraus hergestellte arzneimittel und kosmetika
US5091533A (en) 1990-03-12 1992-02-25 Merck Frosst Canada, Inc. 5-hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors
JPH04217950A (ja) 1990-03-28 1992-08-07 Asahi Chem Ind Co Ltd ヒドロキサム酸誘導体および酵素阻害剤ならびに抗潰瘍剤
JPH03291264A (ja) 1990-04-06 1991-12-20 Japan Tobacco Inc ジメチルアニリン誘導体、その製造方法及びそれを有効成分として含有するガン細胞分化誘導検査試薬及び制癌剤
JPH04187666A (ja) 1990-11-20 1992-07-06 Asahi Chem Ind Co Ltd シクロヘキサンカルボン酸アミド誘導体及び酵素阻害剤ならびに抗潰瘍剤
US5700811A (en) * 1991-10-04 1997-12-23 Sloan-Kettering Institute For Cancer Research Potent inducers of terminal differentiation and method of use thereof
US5369108A (en) * 1991-10-04 1994-11-29 Sloan-Kettering Institute For Cancer Research Potent inducers of terminal differentiation and methods of use thereof
EP0544166A3 (en) * 1991-11-26 1993-11-03 Hoffmann La Roche Cephalosporinderivatives
CA2139325A1 (en) 1992-07-16 1994-02-03 Stephen E. Bales Thiodiphenol copolycarbonates and their use as components of multilayered polymeric reflective bodies
US5783593A (en) 1993-11-04 1998-07-21 Abbott Laboratories Inhibitors of squalene synthetase and protein farnesyltransferase
US5776983A (en) * 1993-12-21 1998-07-07 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
US6008257A (en) * 1994-01-28 1999-12-28 Bayer Aktiengesellschaft Hydroxamic-acid derivatives, method of preparing them and their use as fungicides
GB9420557D0 (en) 1994-10-12 1994-11-30 Zeneca Ltd Aromatic compounds
ATE219765T1 (de) 1995-04-10 2002-07-15 Fujisawa Pharmaceutical Co Indolderivate als cgmp-pde inhibitoren
JPH09165387A (ja) * 1995-09-08 1997-06-24 Univ Princeton 非古典的抗葉酸剤
AU7392696A (en) 1995-10-04 1997-04-28 Warner-Lambert Company Compounds, compositions and methods for inhibiting the binding of proteins containing an sh2 domain to cognate phosphorylated proteins
FR2746098B1 (fr) * 1996-03-14 1998-04-30 Composes propynyl biaromatiques
AUPO118896A0 (en) 1996-07-23 1996-08-15 Fujisawa Pharmaceutical Co., Ltd. New use
RU2171250C2 (ru) 1996-08-05 2001-07-27 Пролинкс, Инк. Производные 2,6-дигидрокси-4-аминометилбензоата
US6174905B1 (en) 1996-09-30 2001-01-16 Mitsui Chemicals, Inc. Cell differentiation inducer
JPH10114654A (ja) 1996-10-09 1998-05-06 Fujisawa Pharmaceut Co Ltd 新規用途
WO1998016514A1 (en) 1996-10-16 1998-04-23 American Cyanamid Company Ortho-sulfonamido bicyclic heteroaryl hydroxamic acids as matrix metalloproteinase and tace inhibitors
US6392010B1 (en) * 1996-12-19 2002-05-21 Aventis Pharmaceuticals Inc. Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
JPH10182583A (ja) 1996-12-25 1998-07-07 Mitsui Chem Inc 新規ヒドロキサム酸誘導体
JP4456183B2 (ja) 1997-01-22 2010-04-28 アベンテイス・フアーマシユーチカルズ・インコーポレーテツド 置換β−チオカルボン酸類
AU726204B2 (en) 1997-02-27 2000-11-02 Wyeth Holdings Corporation N-hydroxy-2-(alkyl, aryl or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors
US6696449B2 (en) 1997-03-04 2004-02-24 Pharmacia Corporation Sulfonyl aryl hydroxamates and their use as matrix metalloprotease inhibitors
JPH10259176A (ja) 1997-03-17 1998-09-29 Japan Tobacco Inc 血管新生阻害作用を有する新規アミド誘導体及びその用途
JPH10287634A (ja) 1997-04-11 1998-10-27 Otsuka Pharmaceut Co Ltd ベンゼン誘導体
HUP0002659A3 (en) 1997-06-17 2002-11-28 Schering Corp Benzo-5,6-cyclohepta[1,2-b]pyridine derivatives, pharmaceutical compositions containing them and their use
DE69824433D1 (en) 1997-08-28 2004-07-15 Biovitrum Ab Proteintyrosinphosphatase inhibitoren
WO1999012884A1 (fr) 1997-09-09 1999-03-18 Shionogi & Co., Ltd. Derives d'acide benzoique a substitution en 4 et cancerostatiques renfermant ces derives comme ingredient actif
ATE242768T1 (de) 1997-10-06 2003-06-15 Wyeth Corp Herstellung und verwendung von ortho-sulfonamido bicyclische heteroaryl hydroxamsäure derivate als matrix-metalloproteinase und tace inhibitoren
AU757630C (en) 1997-10-15 2006-10-26 Wyeth Novel aryloxy-alkyl-dialkylamines
TR200002423T2 (tr) 1998-02-19 2001-01-22 American Cyanamid Company Matriks metaloproteinaz inhibatörler.
EP0960882A1 (en) * 1998-05-19 1999-12-01 Hoechst Marion Roussel Deutschland GmbH Thienyl substituted acylguanidines as inhibitors of bone resorption and vitronectin receptor antagonists
EP1233958B1 (en) * 1999-11-23 2011-06-29 MethylGene Inc. Inhibitors of histone deacetylase
US7288567B2 (en) 2000-03-24 2007-10-30 Methylgene Inc. Inhibitors of histone deacetylase
US6784173B2 (en) * 2001-06-15 2004-08-31 Hoffmann-La Roche Inc. Aromatic dicarboxylic acid derivatives
WO2003055479A1 (en) * 2001-12-21 2003-07-10 Consejo Superior De Investigaciones Cientificas Compounds and their therapeutic use related to the phosphorylating activity of the enzyme gsk-3

Also Published As

Publication number Publication date
CA2507629A1 (en) 2004-07-01
TW200418825A (en) 2004-10-01
PL377696A1 (pl) 2006-02-06
UY28127A1 (es) 2004-06-30
US20040122079A1 (en) 2004-06-24
BR0317348A (pt) 2005-11-16
RU2005122447A (ru) 2006-05-27
EP1575933A1 (en) 2005-09-21
CN100391954C (zh) 2008-06-04
WO2004054999A1 (en) 2004-07-01
CL2003002611A1 (es) 2005-01-14
CN1726204A (zh) 2006-01-25
US7098241B2 (en) 2006-08-29
RU2348625C2 (ru) 2009-03-10
AU2003293882A1 (en) 2004-07-09
PE20040913A1 (es) 2005-01-18
PA8592101A1 (es) 2004-11-02
AR042459A1 (es) 2005-06-22
KR100781929B1 (ko) 2007-12-04
KR20050089157A (ko) 2005-09-07
JP2006513181A (ja) 2006-04-20

Similar Documents

Publication Publication Date Title
GT200300285A (es) Nuevos enantiomeros (r) y (s) de derivados del acido tiofeno hidroxamico
GT200300296A (es) Derivados de pirimidina para el tratamiento del crecimiento celular anormal
CL2003002665A1 (es) COMPUESTOS DERIVADOS DE ACIDOS CARBOXILICOS, SUS SALES; PROCEDIMIENTO DE PREPARACION; COMPOSICION FARMACEUTICA, Y SU USO EN EL TRATAMIENTO DE ENFERMEDADES DONDE ES NECESARIO UN INHIBIDORE DEL FACTOR Xa Y /O UN INHIBIDOR DE SERINA PROTEASA.
GT200600206A (es) Nuevos derivados del fluoreno, composiciones que los contienen y su utilizacion
GT200500103A (es) 4-fenilamino-quinazolin-6-il-amidas
BRPI0518758A2 (pt) compostos de acetamida como fungicidas
GT200300031A (es) Indazoles substitutos, composiciones que los contienen, procedimiento de fabricacion y utilizacion
GT200600329A (es) Fungicidas carboxamidas
GT200200220AA (es) Nuevos derivados de pirrolidina
CY1110209T1 (el) Υποκατεστημενες ενωσεις βενζο(d)ισοξαζολ-3-υλ-αμινης σαν αναλγητικα
BRPI0415855B1 (pt) Processo para preparação de ésteres de ácido 2-dihalogenacil-3-amino-acrílico e ésteres de ácido 3-dihalogeno-metil-pirazol-4-carboxílico
BRPI0613429A2 (pt) inibidores de histona desacetilase
GT200500008A (es) Intermediarios de quinolina como inhibidores de receptores de tirosina quinasas y la sintesis de los mismos
GT200400133A (es) Derivados de pirrolo[3,4-c] pirazol activos como inhibidores de quinasa, proceso para su preparacion y composiciones farmaceuticas que los comprenden
GT200300010A (es) Esteres hidroxamato del acido n-(4-fenil sustituido)-antranilico
GT200300171A (es) Derivados de heterobiarilo como inhibidores de metaloproteinasa de la matriz
ECSP067120A (es) 3-aminociclopentanocarboxamidas como moduladores de receptores de quimioquinas
CR20110381A (es) Antagonistas de 4-azetidinil-1-heteroaril-ciclohexanol de ccr2
UY29149A1 (es) Tiazolil-dihidro-indazoles
GT200200280A (es) Lactamas como antagonistas de taquiquininas
UY31138A1 (es) Derivados de indolinonas sustituidas, composiciones conteniendolos y aplicaciones
BRPI0600194A (pt) composições farmacêuticas contendo docetaxel e um inibidor de degradação e processo de obtenção das mesmas
PA8579901A1 (es) Bifenilcarboxamidas sustituidas con n-aril piperidina
GT200300271A (es) Derivados del acido isoftalico
JO2770B1 (en) Organic compounds