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GT200200242A - Composiciones polimeras de liberacion controlada de compuestos que promueven el crecimiento oseo - Google Patents

Composiciones polimeras de liberacion controlada de compuestos que promueven el crecimiento oseo

Info

Publication number
GT200200242A
GT200200242A GT200200242A GT200200242A GT200200242A GT 200200242 A GT200200242 A GT 200200242A GT 200200242 A GT200200242 A GT 200200242A GT 200200242 A GT200200242 A GT 200200242A GT 200200242 A GT200200242 A GT 200200242A
Authority
GT
Guatemala
Prior art keywords
oseo
growth
promote
compounds
polymer compositions
Prior art date
Application number
GT200200242A
Other languages
English (en)
Inventor
Francis Dumont
Richard Wilker Korsmeyer
Mei Li
Vishwas Madhav Paralkar
Richard Lee Dunn
Scott Alexander Jeffers
Mingxing Zhou
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of GT200200242A publication Critical patent/GT200200242A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN SISTEMA MEJORADO PARA LA LIBERACION CONTROLADA DE UN COMPUESTO QUE PROMUEVE EL CRECIMIENTO OSEO. LA COMPOSICION CONSTA DE UN COMPUESTO QUE PROMUEVE EL CRECIMIENTO OSEO, UN POLIMERO TERMOPLASTICO Y UN DISOLVENTE ORGANICO, ADEMAS, ES CAPAZ DE FORMAR UNA MATRIZ DE POLIMERO SOLIDA, MICROPOROSA, BIODEGRADABLE QUE ES DE UTILIDAD COMO IMPLANTE PARA SUMINISTRAR A CIERTOS TEJIDOS UN COMPUESTO QUE PROMUEVE EL CRECIMIENTO OSEO.
GT200200242A 2001-11-30 2002-11-27 Composiciones polimeras de liberacion controlada de compuestos que promueven el crecimiento oseo GT200200242A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33725501P 2001-11-30 2001-11-30

Publications (1)

Publication Number Publication Date
GT200200242A true GT200200242A (es) 2003-06-25

Family

ID=23319774

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200200242A GT200200242A (es) 2001-11-30 2002-11-27 Composiciones polimeras de liberacion controlada de compuestos que promueven el crecimiento oseo

Country Status (34)

Country Link
US (2) US20030104031A1 (es)
EP (1) EP1448166A1 (es)
JP (1) JP4903985B2 (es)
KR (1) KR100629380B1 (es)
CN (1) CN1599598A (es)
AP (1) AP1781A (es)
AR (1) AR037462A1 (es)
AU (2) AU2002347502A1 (es)
BR (1) BR0214610A (es)
CA (1) CA2468703C (es)
DO (1) DOP2002000534A (es)
EA (1) EA011350B1 (es)
EC (1) ECSP045124A (es)
GE (1) GEP20063951B (es)
GT (1) GT200200242A (es)
HR (1) HRP20040486A2 (es)
HU (1) HUP0402135A3 (es)
IL (1) IL161835A0 (es)
IS (1) IS7217A (es)
MA (1) MA27084A1 (es)
MX (1) MXPA04003723A (es)
NO (1) NO20042273L (es)
NZ (1) NZ533115A (es)
OA (1) OA12731A (es)
PA (1) PA8559001A1 (es)
PE (1) PE20030581A1 (es)
PL (1) PL370085A1 (es)
SV (1) SV2004001421A (es)
TN (1) TNSN04096A1 (es)
TW (1) TW200300695A (es)
UA (1) UA76792C2 (es)
WO (1) WO2003045351A1 (es)
YU (1) YU35004A (es)
ZA (1) ZA200402755B (es)

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US7074425B2 (en) * 2002-09-26 2006-07-11 Bonewax, Llc Hemostatic compositions and methods
EP1596765A2 (en) * 2003-02-10 2005-11-23 Smith & Nephew, Inc. Resorbable devices
GB0307011D0 (en) 2003-03-27 2003-04-30 Regentec Ltd Porous matrix
CA2540586A1 (en) * 2003-10-01 2005-04-21 Optimer Pharmaceuticals, Inc. Treatment of a condition in a mammal with administration of aminosugar and uses thereof
GB0329654D0 (en) 2003-12-23 2004-01-28 Smith & Nephew Tunable segmented polyacetal
US8123787B2 (en) 2004-10-28 2012-02-28 Ogilvie James W Method of treating scoliosis using a biological implant
US8641738B1 (en) 2004-10-28 2014-02-04 James W. Ogilvie Method of treating scoliosis using a biological implant
WO2007020432A2 (en) * 2005-08-18 2007-02-22 Smith & Nephew, Plc High strength devices and composites
CN100443065C (zh) * 2006-01-26 2008-12-17 上海交通大学 用于颌面骨缺损修复的复合体系植入体单元
CA2679365C (en) 2006-11-30 2016-05-03 Smith & Nephew, Inc. Fiber reinforced composite material
EP2142353A1 (en) 2007-04-18 2010-01-13 Smith & Nephew PLC Expansion moulding of shape memory polymers
EP2150288B1 (en) 2007-04-19 2011-04-13 Smith & Nephew, Inc. Graft fixation
JP5520814B2 (ja) 2007-04-19 2014-06-11 スミス アンド ネフュー インコーポレーテッド マルチモーダル形状記憶ポリマー
US8062739B2 (en) * 2007-08-31 2011-11-22 Zimmer, Inc. Hydrogels with gradient
US20090181068A1 (en) * 2008-01-14 2009-07-16 Dunn Richard L Low Viscosity Liquid Polymeric Delivery System
PL2323623T3 (pl) 2008-08-12 2017-04-28 Novartis Ag Kompozycje farmaceutyczne
EP2172189A1 (en) * 2008-10-01 2010-04-07 Novartis AG Pharmaceutical Compositions
US9642658B2 (en) 2008-10-15 2017-05-09 Orthoclip Llc Device and method for delivery of therapeutic agents via internal implants
WO2010045487A1 (en) * 2008-10-15 2010-04-22 Palmetto Biomedical, Inc. Device and method for delivery of therapeutic agents via internal implants
BR112012002341A8 (pt) 2009-08-06 2017-10-10 Koninklijke Philips Electronics Nv Semente radioativa para uso na terapia oncológica e método de terapia oncológica
AU2013201121A1 (en) 2011-09-20 2013-04-04 Vical Incorporated Synergistic anti-tumor efficacy using alloantigen combination immunotherapy
CN104189954B (zh) * 2014-09-19 2017-03-29 中国科学院长春应用化学研究所 一种原位固化组织工程支架及其制备方法
RU2571548C1 (ru) * 2014-12-17 2015-12-20 Федеральное государственное бюджетное учреждение науки Институт органической и физической химии им. А.Е. Арбузова Казанского научного центра Российской академии наук Ветеринарное имплантируемое средство пролонгированного действия (варианты)
US10406098B2 (en) 2015-11-16 2019-09-10 Evonik Roehm Gmbh Injection solution comprising a non-nucleoside reverse-transcriptase inhibitor and poly(lactide-co-glycolide)
CN109498852B (zh) * 2018-12-29 2022-06-24 广州噢斯荣医药技术有限公司 治疗骨科疾病的生物降解材料及其应用
JP2023500506A (ja) 2019-11-04 2023-01-06 アストラゼネカ・アクチエボラーグ 癌を治療するための組み合わせ療法
WO2022144810A1 (en) 2020-12-29 2022-07-07 Sino Medical Sciences Technology Inc. Drug eluting stent
WO2024089417A1 (en) 2022-10-24 2024-05-02 Memorial Sloan-Kettering Cancer Center Tumour stratification for responsiveness to an immune checkpoint inhibitor
EP4608390A1 (en) 2022-10-24 2025-09-03 Cancer Research Technology Limited Tumour sensitisation to checkpoint inhibitors with redox status modifier
EP4649173A1 (en) 2023-01-13 2025-11-19 Akrivia Biomedics Limited Method of profiling diseases
NL2037811B1 (en) 2024-05-29 2025-12-12 Univ Oslo Treatment for Cancer
GB202408360D0 (en) 2024-06-11 2024-07-24 Cancer Research Tech Ltd Tumour sensitisation

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ATE241394T1 (de) * 1994-04-08 2003-06-15 Atrix Lab Inc Beigeordnetes polymersystem zur verwendung mit einer medizinischen vorrichtung
AU4652596A (en) 1995-01-09 1996-07-31 Atrix Laboratories, Inc. Liquid polymer delivery system
WO1998027962A2 (en) * 1996-12-20 1998-07-02 Alza Corporation Injectable depot gel composition and method of preparing the composition
UA59384C2 (uk) * 1996-12-20 2003-09-15 Пфайзер, Інк. Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі
UA67754C2 (uk) * 1997-10-10 2004-07-15 Пфайзер, Інк. Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти)
US7128927B1 (en) * 1998-04-14 2006-10-31 Qlt Usa, Inc. Emulsions for in-situ delivery systems
US6143314A (en) * 1998-10-28 2000-11-07 Atrix Laboratories, Inc. Controlled release liquid delivery compositions with low initial drug burst

Also Published As

Publication number Publication date
TNSN04096A1 (fr) 2006-06-01
AU2009200125B2 (en) 2012-02-02
US20090169595A1 (en) 2009-07-02
ZA200402755B (en) 2005-04-08
MA27084A1 (fr) 2004-12-20
AU2002347502A1 (en) 2003-06-10
YU35004A (sh) 2006-08-17
CA2468703C (en) 2009-12-29
NZ533115A (en) 2005-12-23
WO2003045351A1 (en) 2003-06-05
BR0214610A (pt) 2004-09-14
EP1448166A1 (en) 2004-08-25
HUP0402135A3 (en) 2008-04-28
KR100629380B1 (ko) 2006-09-29
PL370085A1 (en) 2005-05-16
AP2004003037A0 (en) 2004-06-30
CA2468703A1 (en) 2003-06-05
MXPA04003723A (es) 2005-04-08
PA8559001A1 (es) 2003-11-12
HRP20040486A2 (en) 2004-10-31
JP4903985B2 (ja) 2012-03-28
IS7217A (is) 2004-04-07
HUP0402135A2 (hu) 2005-02-28
DOP2002000534A (es) 2003-05-31
UA76792C2 (uk) 2006-09-15
EA200400608A1 (ru) 2004-10-28
PE20030581A1 (es) 2003-07-08
SV2004001421A (es) 2004-05-07
TW200300695A (en) 2003-06-16
OA12731A (en) 2006-06-28
AP1781A (en) 2007-09-27
EA011350B1 (ru) 2009-02-27
CN1599598A (zh) 2005-03-23
JP2005515190A (ja) 2005-05-26
KR20040062977A (ko) 2004-07-09
NO20042273L (no) 2004-07-14
IL161835A0 (en) 2005-11-20
AR037462A1 (es) 2004-11-10
AU2009200125A1 (en) 2009-02-05
GEP20063951B (en) 2006-10-25
ECSP045124A (es) 2004-07-23
US20030104031A1 (en) 2003-06-05
US8017144B2 (en) 2011-09-13

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