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GR1004600B - METHOD OF PREPARATION AND SYNTHESIS OF A KIT AND KIT FOR THE PREPARATION OF THE PEPTIDE C-AcaQALGNQAVGHLMNH2, ANALOGUE OF BOMBESIN (BN2), RADIO-LABELLED WITH THE RADIONUCLIDES Tc-99m AND rE-188. CLINICAL APPLICATION OF THE LABELLED ANALOGUES IN THE DIAGNOSIS AND THERAPY OF CANCER TUMOUR - Google Patents

METHOD OF PREPARATION AND SYNTHESIS OF A KIT AND KIT FOR THE PREPARATION OF THE PEPTIDE C-AcaQALGNQAVGHLMNH2, ANALOGUE OF BOMBESIN (BN2), RADIO-LABELLED WITH THE RADIONUCLIDES Tc-99m AND rE-188. CLINICAL APPLICATION OF THE LABELLED ANALOGUES IN THE DIAGNOSIS AND THERAPY OF CANCER TUMOUR

Info

Publication number
GR1004600B
GR1004600B GR20020100277A GR2002100277A GR1004600B GR 1004600 B GR1004600 B GR 1004600B GR 20020100277 A GR20020100277 A GR 20020100277A GR 2002100277 A GR2002100277 A GR 2002100277A GR 1004600 B GR1004600 B GR 1004600B
Authority
GR
Greece
Prior art keywords
preparation
kit
labelled
radionuclides
diagnosis
Prior art date
Application number
GR20020100277A
Other languages
Greek (el)
Other versions
GR20020100277A (en
Inventor
Αλεξανδρα Βαρβαρηγου
Γρηγοριος Ευαγγελατος
Σπυριδων Αρχιμανδριτης
Original Assignee
Βιομεντικα Λαιφ Σαιενσις Ανωνυμη Εταιρια Φαρμακευτικων Προιοντων
Εθνικο Κεντρο Ερευνας Φυσικων Επιστημων (Ε.Κ.Ε.Φ.Ε.) "Δημοκριτος"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Βιομεντικα Λαιφ Σαιενσις Ανωνυμη Εταιρια Φαρμακευτικων Προιοντων, Εθνικο Κεντρο Ερευνας Φυσικων Επιστημων (Ε.Κ.Ε.Φ.Ε.) "Δημοκριτος" filed Critical Βιομεντικα Λαιφ Σαιενσις Ανωνυμη Εταιρια Φαρμακευτικων Προιοντων
Priority to GR20020100277A priority Critical patent/GR1004600B/en
Priority to PCT/GR2003/000023 priority patent/WO2003104267A1/en
Priority to AU2003232945A priority patent/AU2003232945A1/en
Publication of GR20020100277A publication Critical patent/GR20020100277A/en
Publication of GR1004600B publication Critical patent/GR1004600B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C07K7/086—Bombesin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

he present invention concerns the method of preparation of a pentadecapeptide Bombesin analogue (BN) of the C-Aca-QALGNQAVGHLMNH2 structure for labelling with the radionuclides 99m technetium and 188-rhenium, for their preparation in nuclear medicine laboratories for use in the diagnosis and therapy of cancer tumours.
GR20020100277A 2002-06-10 2002-06-10 METHOD OF PREPARATION AND SYNTHESIS OF A KIT AND KIT FOR THE PREPARATION OF THE PEPTIDE C-AcaQALGNQAVGHLMNH2, ANALOGUE OF BOMBESIN (BN2), RADIO-LABELLED WITH THE RADIONUCLIDES Tc-99m AND rE-188. CLINICAL APPLICATION OF THE LABELLED ANALOGUES IN THE DIAGNOSIS AND THERAPY OF CANCER TUMOUR GR1004600B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GR20020100277A GR1004600B (en) 2002-06-10 2002-06-10 METHOD OF PREPARATION AND SYNTHESIS OF A KIT AND KIT FOR THE PREPARATION OF THE PEPTIDE C-AcaQALGNQAVGHLMNH2, ANALOGUE OF BOMBESIN (BN2), RADIO-LABELLED WITH THE RADIONUCLIDES Tc-99m AND rE-188. CLINICAL APPLICATION OF THE LABELLED ANALOGUES IN THE DIAGNOSIS AND THERAPY OF CANCER TUMOUR
PCT/GR2003/000023 WO2003104267A1 (en) 2002-06-10 2003-06-10 Kit formulation of a novel peptide c-aca-qalgnqwavghlmnh2
AU2003232945A AU2003232945A1 (en) 2002-06-10 2003-06-10 Kit formulation of a novel peptide c-aca-qalgnqwavghlmnh2

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20020100277A GR1004600B (en) 2002-06-10 2002-06-10 METHOD OF PREPARATION AND SYNTHESIS OF A KIT AND KIT FOR THE PREPARATION OF THE PEPTIDE C-AcaQALGNQAVGHLMNH2, ANALOGUE OF BOMBESIN (BN2), RADIO-LABELLED WITH THE RADIONUCLIDES Tc-99m AND rE-188. CLINICAL APPLICATION OF THE LABELLED ANALOGUES IN THE DIAGNOSIS AND THERAPY OF CANCER TUMOUR

Publications (2)

Publication Number Publication Date
GR20020100277A GR20020100277A (en) 2004-02-25
GR1004600B true GR1004600B (en) 2004-06-18

Family

ID=29726799

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20020100277A GR1004600B (en) 2002-06-10 2002-06-10 METHOD OF PREPARATION AND SYNTHESIS OF A KIT AND KIT FOR THE PREPARATION OF THE PEPTIDE C-AcaQALGNQAVGHLMNH2, ANALOGUE OF BOMBESIN (BN2), RADIO-LABELLED WITH THE RADIONUCLIDES Tc-99m AND rE-188. CLINICAL APPLICATION OF THE LABELLED ANALOGUES IN THE DIAGNOSIS AND THERAPY OF CANCER TUMOUR

Country Status (3)

Country Link
AU (1) AU2003232945A1 (en)
GR (1) GR1004600B (en)
WO (1) WO2003104267A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101138634A (en) * 2006-09-07 2008-03-12 于保法 Composition for treating tumour
EA201791126A1 (en) 2014-11-26 2017-11-30 Баофа Ю CHEMIOIMUNOTHERAPY ENHANCED BY HAPTENES IN THE FORM OF PERSONALIZED INTRA-TUMOR CHEMICAL IMMUNOTHERAPY WITH A SUPER MINIMUM CUT
RU2751103C1 (en) * 2020-06-04 2021-07-08 Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" ("Томский НИМЦ") Method for radionuclide diagnostics of lung cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR1003661B (en) * 2000-05-25 2001-09-05 Εθνικο Κεντρο Ερευνας Φυσικων Επιστημων (Εκεφε) "Δημοκριτος"... SYNTHESIS, BIOLOGICAL AND PRECLINICAL EVALUATION OF (D-PHE6, LEU-NHEt13, des-Met14)BOMBESIN(6-14) ANALOGS MIDIFIED WITH 1,4,8,11-TETRAAZAUNDECANE DERIVATIVES AND LABELLED WITH TECHNETIUM-99M ÷OR APPLICATION IN ONCOLOGY

Also Published As

Publication number Publication date
AU2003232945A8 (en) 2003-12-22
AU2003232945A1 (en) 2003-12-22
GR20020100277A (en) 2004-02-25
WO2003104267A1 (en) 2003-12-18

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