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GR1004516B - Multi-functional dendrimers and hyperbranced polymers as drus delivery systems - Google Patents

Multi-functional dendrimers and hyperbranced polymers as drus delivery systems

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Publication number
GR1004516B
GR1004516B GR20030100069A GR2003100069A GR1004516B GR 1004516 B GR1004516 B GR 1004516B GR 20030100069 A GR20030100069 A GR 20030100069A GR 2003100069 A GR2003100069 A GR 2003100069A GR 1004516 B GR1004516 B GR 1004516B
Authority
GR
Greece
Prior art keywords
delivery systems
functional
drus
polymers
synthesis
Prior art date
Application number
GR20030100069A
Other languages
Greek (el)
Inventor
Κωνσταντινος Παλαιος
Δημητριος Τσιουρβας
Ωραιοζηλη Σιδερατου
Original Assignee
Εθνικο Κεντρο Ερευνας Φυσικων Επιστημων (Εκεφε) - "Δημοκριτος"
Κωνσταντινος Παλαιος
Δημητριος Τσιουρβας
Ωραιοζηλη Σιδερατου
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Εθνικο Κεντρο Ερευνας Φυσικων Επιστημων (Εκεφε) - "Δημοκριτος", Κωνσταντινος Παλαιος, Δημητριος Τσιουρβας, Ωραιοζηλη Σιδερατου filed Critical Εθνικο Κεντρο Ερευνας Φυσικων Επιστημων (Εκεφε) - "Δημοκριτος"
Priority to GR20030100069A priority Critical patent/GR1004516B/en
Publication of GR1004516B publication Critical patent/GR1004516B/en

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  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

he present invention deals with thw synthesis of multi-functional dentimeric and hyperbranched polymers in order that they can be used as drug delivery systems of bioactive pharmaceutical compounds. More specifically, the present invention deals with the synthesis of multi-functional compounds based on appropriate dendrimeric or hyperbranched polymers at the external surface of which have been introduced functional groups X,Y, Z. These functional groups render the delivery systems recognizableby their complementary cell receptors. In addition they render the systems stable in the biological milieu and facilitate their transport through cell membrane.
GR20030100069A 2003-02-13 2003-02-13 Multi-functional dendrimers and hyperbranced polymers as drus delivery systems GR1004516B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GR20030100069A GR1004516B (en) 2003-02-13 2003-02-13 Multi-functional dendrimers and hyperbranced polymers as drus delivery systems

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20030100069A GR1004516B (en) 2003-02-13 2003-02-13 Multi-functional dendrimers and hyperbranced polymers as drus delivery systems

Publications (1)

Publication Number Publication Date
GR1004516B true GR1004516B (en) 2004-04-06

Family

ID=32259823

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20030100069A GR1004516B (en) 2003-02-13 2003-02-13 Multi-functional dendrimers and hyperbranced polymers as drus delivery systems

Country Status (1)

Country Link
GR (1) GR1004516B (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6190650B1 (en) * 1994-06-15 2001-02-20 Biomolecular Research Institute Ltd. Antiviral dendrimers
US6455071B1 (en) * 1997-08-27 2002-09-24 Isis Innovation, Ltd. Branched dendrimeric structures

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6190650B1 (en) * 1994-06-15 2001-02-20 Biomolecular Research Institute Ltd. Antiviral dendrimers
US6455071B1 (en) * 1997-08-27 2002-09-24 Isis Innovation, Ltd. Branched dendrimeric structures

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
MINGJUN LIU, KENJI KONO, JEAN M. J. FRÉCHÉT: "Water-Soluble Dendrimer-Poly(ethylene glycol) Starlike Conjugates as Potential Drug Carriers", JOURNAL OF POLYMER SCIENCE: PART A: POLYMER CHEMISTRY, vol. 37, - 1999, pages 3492 - 3503, XP002253701 *
SIDERATOU Z., FOUNDIS J., TSIOURVAS D., NEZIS I., PAPADIMAS G. AND PALEOS C. M.: "A novel dendrimeric "glue" for adhesion of phosphatidyl choline-based liposomes", LANGMUIR, vol. 18, no. 13, - 25 June 2002 (2002-06-25), Washington, DC, USA, pages 5036 - 5039, XP002253699 *
SIDERATOU Z., TSIOURVAS D. AND PALEOS C. M.: "Quaternized poly(propylene imine) dendirmers as novel pH-sensitive controlled-release systems", LANGMUIR, vol. 16, no. 4, - 2000, Washington, DC, USA, pages 1766 - 1769, XP002253698 *
TSIOURVAS D., STATHOPOULOU K., SIDERATOU Z. AND PAELOS C. M.: "Body-centered-cubic derived from n-dodecylurea functionalized poly(propylene imine) dendrimers", MACROMOLECULES, vol. 35, no. 5, - 26 February 2002 (2002-02-26), pages 1746 - 1750, XP002253700 *

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