GR1003598B - Technical description of an "oral solution of chlorhexidine and phenoxyethanol in the correct proportions so as to ensure synergistic antimicrobial action - Google Patents
Technical description of an "oral solution of chlorhexidine and phenoxyethanol in the correct proportions so as to ensure synergistic antimicrobial actionInfo
- Publication number
- GR1003598B GR1003598B GR20000100222A GR2000100222A GR1003598B GR 1003598 B GR1003598 B GR 1003598B GR 20000100222 A GR20000100222 A GR 20000100222A GR 2000100222 A GR2000100222 A GR 2000100222A GR 1003598 B GR1003598 B GR 1003598B
- Authority
- GR
- Greece
- Prior art keywords
- chlorhexidine
- phenoxyethanol
- oral solution
- technical description
- antimicrobial action
- Prior art date
Links
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 title abstract 4
- 229960003260 chlorhexidine Drugs 0.000 title abstract 4
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 title abstract 3
- 229960005323 phenoxyethanol Drugs 0.000 title abstract 3
- 230000002195 synergetic effect Effects 0.000 title abstract 3
- 230000000845 anti-microbial effect Effects 0.000 title abstract 2
- 229940100688 oral solution Drugs 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 208000004509 Tooth Discoloration Diseases 0.000 abstract 1
- 206010044032 Tooth discolouration Diseases 0.000 abstract 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 abstract 1
- 235000019658 bitter taste Nutrition 0.000 abstract 1
- 208000002925 dental caries Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 abstract 1
- 235000003599 food sweetener Nutrition 0.000 abstract 1
- 238000009533 lab test Methods 0.000 abstract 1
- 230000000873 masking effect Effects 0.000 abstract 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 abstract 1
- 230000002906 microbiologic effect Effects 0.000 abstract 1
- 239000003765 sweetening agent Substances 0.000 abstract 1
- 235000019640 taste Nutrition 0.000 abstract 1
- 230000036367 tooth discoloration Effects 0.000 abstract 1
- 235000010447 xylitol Nutrition 0.000 abstract 1
- 239000000811 xylitol Substances 0.000 abstract 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 abstract 1
- 229960002675 xylitol Drugs 0.000 abstract 1
Landscapes
- Cosmetics (AREA)
Abstract
The invention relates to an oral solution with a synergistic action of chlorhexidine and phenoxyethanol in appropriate proportions, which gives very good antimicrobial results and in parallel reduces the undesired effects of chlorhexidine. The formula has an acceptable taste and is effective, as demonstrated by microbiological laboratory tests. The low chlorhexidine content of 0.0125% in the product and the synergistic action of phenoxyethanol 0.55%, with the supporting function of xylitol used as a sweetener in a proportion of 15% to protect the teeth from caries, result in masking the bitter taste, avoiding tooth discoloration even after daily use, and reducing the proportion of ethyl alcohol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR20000100222A GR1003598B (en) | 2000-07-05 | 2000-07-05 | Technical description of an "oral solution of chlorhexidine and phenoxyethanol in the correct proportions so as to ensure synergistic antimicrobial action |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR20000100222A GR1003598B (en) | 2000-07-05 | 2000-07-05 | Technical description of an "oral solution of chlorhexidine and phenoxyethanol in the correct proportions so as to ensure synergistic antimicrobial action |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR1003598B true GR1003598B (en) | 2001-06-14 |
Family
ID=10944314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR20000100222A GR1003598B (en) | 2000-07-05 | 2000-07-05 | Technical description of an "oral solution of chlorhexidine and phenoxyethanol in the correct proportions so as to ensure synergistic antimicrobial action |
Country Status (1)
| Country | Link |
|---|---|
| GR (1) | GR1003598B (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3992519A (en) * | 1974-08-01 | 1976-11-16 | Beecham Group Limited | Oral hygiene compositions |
| WO1987000005A1 (en) * | 1985-07-01 | 1987-01-15 | Dermaci Ab | A COMPOSITION FOR DISINFECTION OF THE VAGINAL AND OTHER MUCOUS MEMBRANES WITH LOW pH |
| EP0231080A1 (en) * | 1986-01-16 | 1987-08-05 | Imperial Chemical Industries Plc | Antiseptic compositions |
| EP0605321A1 (en) * | 1992-12-30 | 1994-07-06 | L'oreal | Antibacterial buccal composition to avoid the formation of dental plaque |
| EP0815832A2 (en) * | 1996-07-01 | 1998-01-07 | Chris Cardon | Kit for pharmaceutical preparations for dent and mouth care |
-
2000
- 2000-07-05 GR GR20000100222A patent/GR1003598B/en unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3992519A (en) * | 1974-08-01 | 1976-11-16 | Beecham Group Limited | Oral hygiene compositions |
| WO1987000005A1 (en) * | 1985-07-01 | 1987-01-15 | Dermaci Ab | A COMPOSITION FOR DISINFECTION OF THE VAGINAL AND OTHER MUCOUS MEMBRANES WITH LOW pH |
| EP0231080A1 (en) * | 1986-01-16 | 1987-08-05 | Imperial Chemical Industries Plc | Antiseptic compositions |
| EP0605321A1 (en) * | 1992-12-30 | 1994-07-06 | L'oreal | Antibacterial buccal composition to avoid the formation of dental plaque |
| EP0815832A2 (en) * | 1996-07-01 | 1998-01-07 | Chris Cardon | Kit for pharmaceutical preparations for dent and mouth care |
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