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GB858188A - Novel dibenzocycloheptaenes and salts thereof and a process for the manufacture of same - Google Patents

Novel dibenzocycloheptaenes and salts thereof and a process for the manufacture of same

Info

Publication number
GB858188A
GB858188A GB13815/60A GB1381560A GB858188A GB 858188 A GB858188 A GB 858188A GB 13815/60 A GB13815/60 A GB 13815/60A GB 1381560 A GB1381560 A GB 1381560A GB 858188 A GB858188 A GB 858188A
Authority
GB
United Kingdom
Prior art keywords
salts
dibenzocycloheptaenes
double bond
novel
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB13815/60A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB858188A publication Critical patent/GB858188A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/02—Acyclic alcohols with carbon-to-carbon double bonds
    • C07C33/025—Acyclic alcohols with carbon-to-carbon double bonds with only one double bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention comprises 5-substituted-dibenzoheptadienes and 5-substituent dibenzocycloheptatrienes having the nucleus <FORM:0858188/IV(b)/1> wherein the broken line represents an optional double bond; the 5-substitutent being an alkyl radical of more than two carbon atoms bearing one or more di-substituted amino groups, e.g. dialkylamino, piperidino, morpholino, or thiamorpholino groups and corresponding compounds bearing one or more nuclear alkyl, alkoxy or halogen substituents and acid addition or quaternary salts thereof. The compounds are prepared by hydrogenating the semi-cyclic double bond of a corresponding 5-aminoalkylidenedibenzocycloheptadi (or tri) ene. Specification 858,187 also is referred to.
GB13815/60A 1953-04-03 1959-03-24 Novel dibenzocycloheptaenes and salts thereof and a process for the manufacture of same Expired GB858188A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH858188X 1953-04-03

Publications (1)

Publication Number Publication Date
GB858188A true GB858188A (en) 1961-01-11

Family

ID=4542881

Family Applications (1)

Application Number Title Priority Date Filing Date
GB13815/60A Expired GB858188A (en) 1953-04-03 1959-03-24 Novel dibenzocycloheptaenes and salts thereof and a process for the manufacture of same

Country Status (1)

Country Link
GB (1) GB858188A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3205264A (en) * 1962-06-15 1965-09-07 Merck & Co Inc Process for the preparation of 10, 11-dihydro-5-(gamma-methyl-and dimethyl-amino propylidene)-5h-dibenzo[a, d] cycloheptene
US3258488A (en) * 1963-08-12 1966-06-28 Colgate Palmolive Co Dibenzo[a, d]cycloheptene derivatives
US3258399A (en) * 1962-09-13 1966-06-28 Colgate Palmolive Co Method of inducing central nervous system stimulation
US3309404A (en) * 1962-04-04 1967-03-14 Merck & Co Inc Derivatives of dibenzocycloheptenes and a process for their preparation
DE1290541B (en) * 1961-02-10 1969-03-13 Ayerst Mckenna & Harrison Dimethylaminopropyl dibenzocycloheptene compounds and process for their preparation
US3978121A (en) * 1963-07-25 1976-08-31 Merck & Co., Inc. 5H Dibenzo[a,d]cycloheptene derivatives

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1290541B (en) * 1961-02-10 1969-03-13 Ayerst Mckenna & Harrison Dimethylaminopropyl dibenzocycloheptene compounds and process for their preparation
US3309404A (en) * 1962-04-04 1967-03-14 Merck & Co Inc Derivatives of dibenzocycloheptenes and a process for their preparation
US3205264A (en) * 1962-06-15 1965-09-07 Merck & Co Inc Process for the preparation of 10, 11-dihydro-5-(gamma-methyl-and dimethyl-amino propylidene)-5h-dibenzo[a, d] cycloheptene
US3258399A (en) * 1962-09-13 1966-06-28 Colgate Palmolive Co Method of inducing central nervous system stimulation
US3978121A (en) * 1963-07-25 1976-08-31 Merck & Co., Inc. 5H Dibenzo[a,d]cycloheptene derivatives
US3258488A (en) * 1963-08-12 1966-06-28 Colgate Palmolive Co Dibenzo[a, d]cycloheptene derivatives

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