GB857148A - Sulphonyl-urethanes and process for their manufacture - Google Patents
Sulphonyl-urethanes and process for their manufactureInfo
- Publication number
- GB857148A GB857148A GB13620/57A GB1362057A GB857148A GB 857148 A GB857148 A GB 857148A GB 13620/57 A GB13620/57 A GB 13620/57A GB 1362057 A GB1362057 A GB 1362057A GB 857148 A GB857148 A GB 857148A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carbon atoms
- group
- reacting
- sulphonyl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/53—X and Y not being nitrogen atoms, e.g. N-sulfonylcarbamic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention comprises sulphonylurethanes of the general formula : R-SO2-NH-COOR1 (wherein R represents a phenyl group which may be substituted by one or by two identical or different alkyl or alkoxy groups of at most 6 carbon atoms or by one such alkyl group and one such alkoxy group, or represents a naphthyl-(2), 5 : 6 : 7 : 8-tetrahydronaphthyl-(2), 4-phenoxyphenyl or 4-diphenylyl group or an alkyl, cycloalkyl or cycloalkyl-alkyl group of 3-8 carbon atoms, and R1 represents an aliphatic radical of 4-8 carbon atoms or an araliphatic radical whose alkylene group contains 2-4 carbon atoms) and their alkali metal salts, and the preparation thereof by reacting an appropriate alcohol R1OH with a sulphonylisocyanate R-SO2-NCO or a corresponding N1-sulphonyl-N2-disubstituted urea, or by re-esterifying an R-substituted sulphonylurethane of another alcohol with an alcohol R1OH, or by reacting a sulphonamide R-SO2NH2, or preferably an alkali metal salt thereof, with a haloformic ester of an alcohol R1OH. The products are useful for oral administration in the treatment of diabetes mellitus. N-(4-Methylbenzenesulphonyl)-N1-diphenylurea is prepared by reacting N-(4-methylbenzene-sulphonyl)-isocyanate with diphenylamine.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE857148X | 1956-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB857148A true GB857148A (en) | 1960-12-29 |
Family
ID=6789500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB13620/57A Expired GB857148A (en) | 1956-04-28 | 1957-04-29 | Sulphonyl-urethanes and process for their manufacture |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB857148A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3377375A (en) * | 1963-02-07 | 1968-04-09 | Monsanto Co | N-aralkylsulfonyl carbamates |
-
1957
- 1957-04-29 GB GB13620/57A patent/GB857148A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3377375A (en) * | 1963-02-07 | 1968-04-09 | Monsanto Co | N-aralkylsulfonyl carbamates |
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