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GB725812A - Succinimide compounds and method for obtaining the same - Google Patents

Succinimide compounds and method for obtaining the same

Info

Publication number
GB725812A
GB725812A GB2252/53A GB225253A GB725812A GB 725812 A GB725812 A GB 725812A GB 2252/53 A GB2252/53 A GB 2252/53A GB 225253 A GB225253 A GB 225253A GB 725812 A GB725812 A GB 725812A
Authority
GB
United Kingdom
Prior art keywords
diethyl
methyl
ammonia
methylamine
heating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2252/53A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parke Davis and Co LLC
Original Assignee
Parke Davis and Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parke Davis and Co LLC filed Critical Parke Davis and Co LLC
Publication of GB725812A publication Critical patent/GB725812A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • C07D207/4042,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • C07D207/408Radicals containing only hydrogen and carbon atoms attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)

Abstract

The invention comprises succinimides of the formula <FORM:0725812/IV (b)/1> wherein R is hydrogen or a methyl radical, and their preparation by reacting a : a -diethyl-b -methyl succinic acid or its anhydride with ammonia or methylamine, preferably in an inert solvent, e.g. water, alcohol, ether or benzene, and heating the intermediate product so obtained to a temperature between 100 DEG and 350 DEG C. The intermediate product may be a half-amide, its ammonium or methylamine salt, or a mono- or di-salt of the succinic acid, according to the quantities and reagents taken. In examples: (1) a : a -diethyl-b -methylsuccinic acid is added to concentrated ammonia, water and excess ammonia distilled off and the residue, after heating to 200 DEG C., is purified to yield a : a -diethyl-b -methylsuccinimide; (2) as in (1) but using the corresponding succinic anhydride; (3) as in (1) but replacing ammonia by aqueous methylamine when N-methyl-a : a -diethyl-b -methyl succinimide is obtained.
GB2252/53A 1952-02-26 1953-01-26 Succinimide compounds and method for obtaining the same Expired GB725812A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US725812XA 1952-02-26 1952-02-26

Publications (1)

Publication Number Publication Date
GB725812A true GB725812A (en) 1955-03-09

Family

ID=22108531

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2252/53A Expired GB725812A (en) 1952-02-26 1953-01-26 Succinimide compounds and method for obtaining the same

Country Status (1)

Country Link
GB (1) GB725812A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3338911A (en) * 1963-07-04 1967-08-29 Desitin Werk Carl Klinke G M B Process for the preparation of alpha, alpha-disubstituted succinimides

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3338911A (en) * 1963-07-04 1967-08-29 Desitin Werk Carl Klinke G M B Process for the preparation of alpha, alpha-disubstituted succinimides

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