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GB579513A - Improvements in or relating to sulphonyl guanidines and methods of preparing same - Google Patents

Improvements in or relating to sulphonyl guanidines and methods of preparing same

Info

Publication number
GB579513A
GB579513A GB8108/43A GB810843A GB579513A GB 579513 A GB579513 A GB 579513A GB 8108/43 A GB8108/43 A GB 8108/43A GB 810843 A GB810843 A GB 810843A GB 579513 A GB579513 A GB 579513A
Authority
GB
United Kingdom
Prior art keywords
benzenesulphonyl
sulphonyl
guanidine
guanyl urea
give
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8108/43A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of GB579513A publication Critical patent/GB579513A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52Y being a hetero atom
    • C07C311/64X and Y being nitrogen atoms, e.g. N-sulfonylguanidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)

Abstract

Sulphonyl guanidines are prepared by subjecting an aliphatic or an aromatic sulphonyl guanyl urea to a heat treatment in the presence of water and a basic substance. If desired, a water-miscible organic solvent may also be present. The sulphonyl guanyl urea may be prepared in any convenient manner, but the preferred method is by the hydrolysis of a sulphonyl dicyandiamide. A preferred embodiment of the present invention is the treatment of sulphanilyl guanyl urea to form sulphanilyl guanidine. As basic substances there are mentioned ammonia, hydroxylamines, hydrazines, guanidines, aliphatic, hydroaromatic, or aromatic primary or secondary amines or polyamines. A large number of individual compounds are named. In examples: (1) Benzenesulphonyl guanidine is prepared by heating benzenesulphonyl dicyandiamide first with aqueous 50 per cent ethyl ether of ethylene glycol and then with aqueous sodium hydroxide. (2) n-Butylsulphonyl guanyl urea is heated with aqueous sodium hydroxide to give n-butylsulphonyl guanidine. (3) Benzenesulphonyl guanyl urea is heated in aqueous sodium hydroxide to give benzenesulphonyl guanidine. (4) Sulphanilyl guanyl urea is heated with aqueous sodium hydroxide to give sulphanilyl guanidine. (5) Benzene sulphonyl guanyl urea is heated with aqueous n-butylamine to give benzenesulphonyl guanidine. (6) Benzenesulphonyl guanyl urea is heated with aqueous sodium carbonate to give benzenesulphonyl guanidine. The Specification contains a list of a large number of sulphonyl guanyl ureas which may be employed as starting materials for the process of the invention. Specification 566,091 is referred to.
GB8108/43A 1942-04-11 1943-05-21 Improvements in or relating to sulphonyl guanidines and methods of preparing same Expired GB579513A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US579513XA 1942-04-11 1942-04-11

Publications (1)

Publication Number Publication Date
GB579513A true GB579513A (en) 1946-08-07

Family

ID=22013735

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8108/43A Expired GB579513A (en) 1942-04-11 1943-05-21 Improvements in or relating to sulphonyl guanidines and methods of preparing same

Country Status (1)

Country Link
GB (1) GB579513A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992008464A1 (en) * 1990-11-15 1992-05-29 Tanabe Seiyaku Co. Ltd. Substituted urea and related cell adhesion modulation compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992008464A1 (en) * 1990-11-15 1992-05-29 Tanabe Seiyaku Co. Ltd. Substituted urea and related cell adhesion modulation compounds

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