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GB2612411A - Novel medicinal compound for combating viral infections like corona virus infection and method of mitigating the conditions - Google Patents

Novel medicinal compound for combating viral infections like corona virus infection and method of mitigating the conditions Download PDF

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Publication number
GB2612411A
GB2612411A GB2211869.9A GB202211869A GB2612411A GB 2612411 A GB2612411 A GB 2612411A GB 202211869 A GB202211869 A GB 202211869A GB 2612411 A GB2612411 A GB 2612411A
Authority
GB
United Kingdom
Prior art keywords
medicinal compound
novel medicinal
compound
viral infections
egcg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB2211869.9A
Other versions
GB202211869D0 (en
Inventor
Sarath Ranaweera Ananda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB202211869D0 publication Critical patent/GB202211869D0/en
Publication of GB2612411A publication Critical patent/GB2612411A/en
Withdrawn legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Insects & Arthropods (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Animal Husbandry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention is a medicinal compound that contains two ingredients that are available in organic products. The compound to be used in the human body to mitigate conditions due to viral infections. Epigallo Catechin gallate (EGCG) is extracted and mixed with bee-honey to be used as oral solution where EGCG is mixed with alcohol to be used as inhalation compound. Protease in the bee-honey causing the damage to the outer layer of the virus where EGCG is used to destroy the RNA of the virus.

Claims (10)

Claims
1. [Claim 1] A novel medicinal compound comprising: Epigallo catechin gallate (EGCG) and protease of bee honey to treat viral infections in the human body.
2. [Claim 2] The novel medicinal compound as claimed in claim 1 characterized in that wherein epigallo catechin is concentrated to 80% above when extracted from tea catechin while removing epicatechin gallate (ECG).
3. [Claim 3] The novel medicinal compound as claimed in claim 1 characterized in that wherein epigallo catechin and protease from bee-honey mixed in the ratio of 3:1 at the temperature range 40 degree Celsius - 45 degree Celsius.
4. [Claim 4] The novel medicinal compound as claimed in claim 3 is recommended 20ml oral dose 3 times a day to effective mitigation and curing of viral invasions in the human body.
5. [Claim 5] A novel medicinal compound comprising: Epigallo catechin gallate (EGCG) and alcohol to treat viral infections in the human body.
6. [Claim 6] The novel medicinal compound as claimed in claim 5 characterized in that wherein epigallo catechin and alcohol is mixed at a pressurized closed environment.
7. [Claim 7] The novel medicinal compound as claimed in claim 5 to be used with patients in critical conditions in mitigating viral infections with humans while taking oral dose of compound claimed in claim 1.
8. [Claim 8] A novel medicinal compound comprising EGCG of tea catechin and protease of bee honey, where in ECG is removed from tea catechin.
9. [Claim 9] Use of novel medicinal compound as claimed in claim 1 to mitigate cancers like brain tumors.
10. [Claim 10] Use of novel medicinal compound as claimed in anyone above in combination as directed by the specialists.
GB2211869.9A 2020-04-03 2020-04-03 Novel medicinal compound for combating viral infections like corona virus infection and method of mitigating the conditions Withdrawn GB2612411A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IB2020/053205 WO2021198739A1 (en) 2020-04-03 2020-04-03 Novel medicinal compound for combating viral infections like corona virus infection and method of mitigating the conditions
CA3092524A CA3092524A1 (en) 2020-04-03 2020-09-09 A novel compound for combating viral infections, mitigating non-transferable deceases and enhancing the immunity in the human body

Publications (2)

Publication Number Publication Date
GB202211869D0 GB202211869D0 (en) 2022-09-28
GB2612411A true GB2612411A (en) 2023-05-03

Family

ID=77928333

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2211869.9A Withdrawn GB2612411A (en) 2020-04-03 2020-04-03 Novel medicinal compound for combating viral infections like corona virus infection and method of mitigating the conditions

Country Status (3)

Country Link
CA (1) CA3092524A1 (en)
GB (1) GB2612411A (en)
WO (1) WO2021198739A1 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090170928A1 (en) * 2005-04-28 2009-07-02 Bruno Ferdinando F Synthesis of oligo/poly(catechins) and methods of use
US20160346308A1 (en) * 2014-02-07 2016-12-01 Shaker A. Mousa Composition and method of use for combinations of anti-viral protease, polymerase inhibitors and natural bioactive compounds in the treatment of hepatitis c infection
US20160361291A1 (en) * 2013-12-18 2016-12-15 Abbott Laboratories Methods for increasing skeletal muscle protein synthesis using green tea extract
US20180177860A1 (en) * 2015-06-11 2018-06-28 Industry-Academic Cooperation Foundation, Yonsei University Vaccine containing virus inactivated by green tea extract, and preparation method therefor
US20200054595A1 (en) * 2018-08-17 2020-02-20 Augusta University Research Institute, Inc. EGCG-Palmitate Compositions and Methods of Use Thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090170928A1 (en) * 2005-04-28 2009-07-02 Bruno Ferdinando F Synthesis of oligo/poly(catechins) and methods of use
US20160361291A1 (en) * 2013-12-18 2016-12-15 Abbott Laboratories Methods for increasing skeletal muscle protein synthesis using green tea extract
US20160346308A1 (en) * 2014-02-07 2016-12-01 Shaker A. Mousa Composition and method of use for combinations of anti-viral protease, polymerase inhibitors and natural bioactive compounds in the treatment of hepatitis c infection
US20180177860A1 (en) * 2015-06-11 2018-06-28 Industry-Academic Cooperation Foundation, Yonsei University Vaccine containing virus inactivated by green tea extract, and preparation method therefor
US20200054595A1 (en) * 2018-08-17 2020-02-20 Augusta University Research Institute, Inc. EGCG-Palmitate Compositions and Methods of Use Thereof

Also Published As

Publication number Publication date
CA3092524A1 (en) 2021-10-03
GB202211869D0 (en) 2022-09-28
WO2021198739A1 (en) 2021-10-07

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Legal Events

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WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)