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GB2523873B - Systems, devices and methods for connecting a chromatography system to a mass spectrometer - Google Patents

Systems, devices and methods for connecting a chromatography system to a mass spectrometer

Info

Publication number
GB2523873B
GB2523873B GB1420981.1A GB201420981A GB2523873B GB 2523873 B GB2523873 B GB 2523873B GB 201420981 A GB201420981 A GB 201420981A GB 2523873 B GB2523873 B GB 2523873B
Authority
GB
United Kingdom
Prior art keywords
systems
methods
devices
mass spectrometer
chromatography system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1420981.1A
Other versions
GB201420981D0 (en
GB2523873A (en
Inventor
Geoff Gerhardt
Michael Fogwill
James Murphy
Joseph Michienzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Waters Technologies Corp
Original Assignee
Waters Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Waters Technologies Corp filed Critical Waters Technologies Corp
Publication of GB201420981D0 publication Critical patent/GB201420981D0/en
Publication of GB2523873A publication Critical patent/GB2523873A/en
Application granted granted Critical
Publication of GB2523873B publication Critical patent/GB2523873B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H01J49/0445—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for introducing as a spray, a jet or an aerosol
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/165—Electrospray ionisation
    • H01J49/167—Capillaries and nozzles specially adapted therefor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Dispersion Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
GB1420981.1A 2013-11-26 2014-11-26 Systems, devices and methods for connecting a chromatography system to a mass spectrometer Active GB2523873B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361098857P 2013-11-26 2013-11-26

Publications (3)

Publication Number Publication Date
GB201420981D0 GB201420981D0 (en) 2015-01-07
GB2523873A GB2523873A (en) 2015-09-09
GB2523873B true GB2523873B (en) 2016-04-20

Family

ID=52292541

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1420981.1A Active GB2523873B (en) 2013-11-26 2014-11-26 Systems, devices and methods for connecting a chromatography system to a mass spectrometer

Country Status (1)

Country Link
GB (1) GB2523873B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110706996B (en) * 2015-03-06 2023-08-11 英国质谱公司 Impact surface for improved ionization
WO2016142691A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Rapid evaporative ionisation mass spectrometry ("reims") and desorption electrospray ionisation mass spectrometry ("desi-ms") analysis of swabs and biopsy samples
CA2978165A1 (en) * 2015-03-06 2016-09-15 Micromass Uk Limited Improved ionisation of gaseous samples
GB2607198A (en) * 2015-03-06 2022-11-30 Micromass Ltd Spectrometric analysis
CN107533032A (en) 2015-03-06 2018-01-02 英国质谱公司 In situ ionization mass spectrometry imaging platform for direct mapping from bulk tissue
US11454611B2 (en) 2016-04-14 2022-09-27 Micromass Uk Limited Spectrometric analysis of plants

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2358924A (en) * 1999-11-25 2001-08-08 Finnigan Mat Gmbh Production of standard gases, CO and hydrogen, for mass spectroscopy
US6586731B1 (en) * 1999-04-12 2003-07-01 Mds Inc. High intensity ion source apparatus for mass spectrometry
WO2007002141A2 (en) * 2005-06-21 2007-01-04 West Virginia University Research Corporation Apparatus and method for coupling microfluidic systems with electrospray ionization mass spectrometry utilizing a hydrodynamic flow restrictor
WO2009094780A1 (en) * 2008-02-01 2009-08-06 Ionics Mass Spectrometry Group, Inc. Ion source vessel and methods
US20120104248A1 (en) * 2010-10-29 2012-05-03 Mark Hardman Combined Ion Source for Electrospray and Atmospheric Pressure Chemical Ionization
US20130068946A1 (en) * 2011-09-16 2013-03-21 Science & Engineering Services, Inc. Thermo-stabilized nano- and micro- flow lc/esi-ms interface and a method thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586731B1 (en) * 1999-04-12 2003-07-01 Mds Inc. High intensity ion source apparatus for mass spectrometry
GB2358924A (en) * 1999-11-25 2001-08-08 Finnigan Mat Gmbh Production of standard gases, CO and hydrogen, for mass spectroscopy
WO2007002141A2 (en) * 2005-06-21 2007-01-04 West Virginia University Research Corporation Apparatus and method for coupling microfluidic systems with electrospray ionization mass spectrometry utilizing a hydrodynamic flow restrictor
WO2009094780A1 (en) * 2008-02-01 2009-08-06 Ionics Mass Spectrometry Group, Inc. Ion source vessel and methods
US20120104248A1 (en) * 2010-10-29 2012-05-03 Mark Hardman Combined Ion Source for Electrospray and Atmospheric Pressure Chemical Ionization
US20130068946A1 (en) * 2011-09-16 2013-03-21 Science & Engineering Services, Inc. Thermo-stabilized nano- and micro- flow lc/esi-ms interface and a method thereof

Also Published As

Publication number Publication date
GB201420981D0 (en) 2015-01-07
GB2523873A (en) 2015-09-09

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