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GB2502016A - Freeze drying method - Google Patents

Freeze drying method Download PDF

Info

Publication number
GB2502016A
GB2502016A GB1314778.0A GB201314778A GB2502016A GB 2502016 A GB2502016 A GB 2502016A GB 201314778 A GB201314778 A GB 201314778A GB 2502016 A GB2502016 A GB 2502016A
Authority
GB
United Kingdom
Prior art keywords
cells
freeze drying
reconstitution
biological material
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB1314778.0A
Other versions
GB2502016B (en
GB201314778D0 (en
Inventor
Ward Kevin
Andrew Cowen
Thomas Peacock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BIOPHARMA TECHNOLOGY Ltd
Original Assignee
BIOPHARMA TECHNOLOGY Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BIOPHARMA TECHNOLOGY Ltd filed Critical BIOPHARMA TECHNOLOGY Ltd
Priority claimed from PCT/GB2012/000051 external-priority patent/WO2012098358A1/en
Publication of GB201314778D0 publication Critical patent/GB201314778D0/en
Publication of GB2502016A publication Critical patent/GB2502016A/en
Application granted granted Critical
Publication of GB2502016B publication Critical patent/GB2502016B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/16—Physical preservation processes
    • A01N1/162—Temperature processes, e.g. following predefined temperature changes over time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Mechanical Engineering (AREA)
  • Environmental Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Dentistry (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to a method of freeze drying, in particular to the freeze drying of cell based biological material and subsequent reconstitution. The biological material may be from any source such as microbial cells, protozoal cells, animal cells or plant cells. In particular the invention relates to freeze drying mammalian cells, such as blood cells, nucleated cells and bacterial cells for therapeutic use and use in food products. The invention further provides a method of reconstitution of the freeze dried cells resulting in better viability and functionality of the cells after reconstitution.
GB1314778.0A 2011-01-20 2012-01-20 Method of freeze drying and reconstituting biological material Active GB2502016B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161461628P 2011-01-20 2011-01-20
GBGB1101002.2A GB201101002D0 (en) 2011-01-20 2011-01-20 Freeze drying method
PCT/GB2012/000051 WO2012098358A1 (en) 2011-01-20 2012-01-20 Freeze drying method

Publications (3)

Publication Number Publication Date
GB201314778D0 GB201314778D0 (en) 2013-10-02
GB2502016A true GB2502016A (en) 2013-11-13
GB2502016B GB2502016B (en) 2018-01-31

Family

ID=43769359

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB1101002.2A Ceased GB201101002D0 (en) 2011-01-20 2011-01-20 Freeze drying method
GB1314778.0A Active GB2502016B (en) 2011-01-20 2012-01-20 Method of freeze drying and reconstituting biological material

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB1101002.2A Ceased GB201101002D0 (en) 2011-01-20 2011-01-20 Freeze drying method

Country Status (1)

Country Link
GB (2) GB201101002D0 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025163153A2 (en) 2024-02-01 2025-08-07 The University Of Bristol Cell compositions and related methods

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0475409A2 (en) * 1990-09-12 1992-03-18 Lifecell Corporation Method and apparatus for cryopreparation, dry stabilization and rehydration of biological suspensions
WO1992014360A1 (en) * 1991-02-15 1992-09-03 Cryopharm Corporation Method of lyophilization and reconstitution of mixtures of nucleated non-mammalian cells and blood matter
WO1993014191A1 (en) * 1992-01-21 1993-07-22 Cryopharm Corporation Method of freezing cells and cell-like materials
EP0668013A2 (en) * 1994-02-22 1995-08-23 Nippon Telegraph And Telephone Corporation Freeze-dried blood cells, stem cells and platelets and manufacturing method for the same
WO2006020773A2 (en) * 2004-08-12 2006-02-23 Adlyfe, Inc. Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use
WO2007015252A2 (en) * 2005-08-03 2007-02-08 I.M.T. Interface Multigrad Technology Ltd. Somatic cells for use in cell therapy

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0475409A2 (en) * 1990-09-12 1992-03-18 Lifecell Corporation Method and apparatus for cryopreparation, dry stabilization and rehydration of biological suspensions
WO1992014360A1 (en) * 1991-02-15 1992-09-03 Cryopharm Corporation Method of lyophilization and reconstitution of mixtures of nucleated non-mammalian cells and blood matter
WO1993014191A1 (en) * 1992-01-21 1993-07-22 Cryopharm Corporation Method of freezing cells and cell-like materials
EP0668013A2 (en) * 1994-02-22 1995-08-23 Nippon Telegraph And Telephone Corporation Freeze-dried blood cells, stem cells and platelets and manufacturing method for the same
WO2006020773A2 (en) * 2004-08-12 2006-02-23 Adlyfe, Inc. Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use
WO2007015252A2 (en) * 2005-08-03 2007-02-08 I.M.T. Interface Multigrad Technology Ltd. Somatic cells for use in cell therapy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025163153A2 (en) 2024-02-01 2025-08-07 The University Of Bristol Cell compositions and related methods

Also Published As

Publication number Publication date
GB2502016B (en) 2018-01-31
GB201314778D0 (en) 2013-10-02
GB201101002D0 (en) 2011-03-09

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