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GB2500552A - Stable lactase drops - Google Patents

Stable lactase drops Download PDF

Info

Publication number
GB2500552A
GB2500552A GB1312849.1A GB201312849A GB2500552A GB 2500552 A GB2500552 A GB 2500552A GB 201312849 A GB201312849 A GB 201312849A GB 2500552 A GB2500552 A GB 2500552A
Authority
GB
United Kingdom
Prior art keywords
drops
stable lactase
stable
lactase drops
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB1312849.1A
Other versions
GB201312849D0 (en
GB2500552A8 (en
Inventor
Nsv Raju
Kandarapu Raghupathi
Maram Sambasivarao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medreich Ltd
Original Assignee
Medreich Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medreich Ltd filed Critical Medreich Ltd
Publication of GB201312849D0 publication Critical patent/GB201312849D0/en
Publication of GB2500552A publication Critical patent/GB2500552A/en
Publication of GB2500552A8 publication Critical patent/GB2500552A8/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01108—Lactase (3.2.1.108)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

The present invention relates to stable lactase drops composition having pH of about 4.0 - 5.0, wherein the composition comprises at least one polyol and one or more buffering agents.
GB1312849.1A 2011-12-05 2012-11-26 Stable lactase drops Withdrawn GB2500552A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN4208CH2011 2011-12-05
PCT/IN2012/000769 WO2013084244A1 (en) 2011-12-05 2012-11-26 Stable lactase drops

Publications (3)

Publication Number Publication Date
GB201312849D0 GB201312849D0 (en) 2013-09-04
GB2500552A true GB2500552A (en) 2013-09-25
GB2500552A8 GB2500552A8 (en) 2014-04-09

Family

ID=48573668

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1312849.1A Withdrawn GB2500552A (en) 2011-12-05 2012-11-26 Stable lactase drops

Country Status (3)

Country Link
EP (1) EP2787972A4 (en)
GB (1) GB2500552A (en)
WO (1) WO2013084244A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112016020077B1 (en) * 2014-03-05 2021-04-13 Dsm Ip Assets B.V. FORMULATION OF STABLE WATER LIQUID LIQUID, PROCESS TO PRODUCE THE SAME, FORMULA AS GRANULATE POWDER FOR INFANTS, TRANSITION OR FOR CHILDREN, AND METHOD TO PRODUCE THE SAME
DK3568023T3 (en) 2017-01-13 2021-10-04 Novozymes As Sterile filtered lactase preparation comprising monovalent cation salt and its preparation
ES3013465T3 (en) * 2019-12-26 2025-04-14 Pharmunion Llc Stable lactase product
JP7706443B2 (en) * 2020-04-17 2025-07-11 合同酒精株式会社 Packaged lactase solution

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2189009A1 (en) * 1972-06-23 1974-01-25 Biochefarm Lactase cntg compsn - for treating milk intolerance
US4464469A (en) * 1981-09-01 1984-08-07 John & E. Sturge Limited Stabilized lactase solutions and processes for stabilization

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3718739A (en) * 1971-06-15 1973-02-27 Baxter Laboratories Inc Treating lactase deficiency with an active lactase

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2189009A1 (en) * 1972-06-23 1974-01-25 Biochefarm Lactase cntg compsn - for treating milk intolerance
US4464469A (en) * 1981-09-01 1984-08-07 John & E. Sturge Limited Stabilized lactase solutions and processes for stabilization

Also Published As

Publication number Publication date
EP2787972A1 (en) 2014-10-15
EP2787972A4 (en) 2015-04-22
WO2013084244A1 (en) 2013-06-13
GB201312849D0 (en) 2013-09-04
GB2500552A8 (en) 2014-04-09

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