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GB2567851A - An energy harvesting device - Google Patents

An energy harvesting device Download PDF

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Publication number
GB2567851A
GB2567851A GB1717653.8A GB201717653A GB2567851A GB 2567851 A GB2567851 A GB 2567851A GB 201717653 A GB201717653 A GB 201717653A GB 2567851 A GB2567851 A GB 2567851A
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United Kingdom
Prior art keywords
energy
harvesting device
energy harvesting
biological cell
biological
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Application number
GB1717653.8A
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GB201717653D0 (en
Inventor
Shakur Rameen
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Individual
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Individual
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Priority to GB1717653.8A priority Critical patent/GB2567851A/en
Publication of GB201717653D0 publication Critical patent/GB201717653D0/en
Publication of GB2567851A publication Critical patent/GB2567851A/en
Withdrawn legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657Cardiomyocytes; Heart cells
    • HELECTRICITY
    • H02GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02NELECTRIC MACHINES NOT OTHERWISE PROVIDED FOR
    • H02N2/00Electric machines in general using piezoelectric effect, electrostriction or magnetostriction
    • H02N2/18Electric machines in general using piezoelectric effect, electrostriction or magnetostriction producing electrical output from mechanical input, e.g. generators
    • H02N2/186Vibration harvesters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0696Artificially induced pluripotent stem cells, e.g. iPS
    • HELECTRICITY
    • H02GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02NELECTRIC MACHINES NOT OTHERWISE PROVIDED FOR
    • H02N2/00Electric machines in general using piezoelectric effect, electrostriction or magnetostriction
    • H02N2/18Electric machines in general using piezoelectric effect, electrostriction or magnetostriction producing electrical output from mechanical input, e.g. generators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2527/00Culture process characterised by the use of mechanical forces, e.g. strain, vibration

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

An energy harvesting device comprises at least one biological cell 105, which may be a cardiomyocyte, a heart or muscle stem cell, or at least one induced pluripotent stem cell (iPSC) line. The biological cell is coupled with a bio-compatible nano-surface 100, which may be a piezoelectric surface, which generates power from the vibrations or mechanical movement of the cells, the electrical power being stored in a storage medium 125, which may be a battery or capacitor.

Description

An Energy Harvesting Device
Technical Field of the Disclosure
The present disclosure relates to an energy harvesting device, particularly but not exclusively, to an energy harvesting device using at least a biological cell.
Background of the Disclosure
Various energy harvesting devices have been reported in the literature, many of them are MEMs cantilever based energy harvesting device. There are very few developments in the field of energy harvesting using biological cells.
Summary of the Disclosure
The present disclosure relates to a renewal biological energy source which allows for the utilization of stem cell technologies in the creation renewable energy. The disclosure proposes an energy storage medium in which the energy source is coming from movement (or beating) of cardiomyocytes stem cells which are coupled with, for example, piezoelectric devices which will convert a vibrational/mechanical energy from the stem cells into potential electrical energy. The energy harvesting device of this proposal will be applicable to low energy renewable applications. The energy harvesting device will be also a low cost portable device which can be readily used.
The device generally uses piezoelectric nano-surfaces or layers on which the monolayer of cardiomyocytes are located. Here the term monolayer means all the cardiomyocytes are formed within one layer which is disposed or dispersed throughout the piezoelectric nano-surface. The advantage of forming the cardiomyocytes in monolayer is that the cardiomyocytes can beat simultaneously which will generate vibrational and/or mechanical energy. The piezoelectric surface then converts the vibrational and/or mechanical energy into the electrical potential energy. There is a controller which generally transmits the electrical energy through an energy storage device such as a capacitor or battery. In the end, the energy harvesting device generally operates as an energy storage device. In one embodiment, the piezoelectric nano-surface of this disclosure is a piezoelectric capacitance device.
According to one aspect of the present invention, there is provided an energy harvesting device comprising:
at least one biological cell;
a bio-compatible surface coupled with said at least one biological cell; wherein the bio-compatible surface is configured such that a vibrational and/or mechanical energy from the at least one biological cell is converted to an electrical potential energy for storage in a storage medium.
The at least one biological cell may comprise at least one stem cell.
The at least one biological cell may be at least one induced pluripotent stem cell (iPSC) line.
The induced pluripotent stem cell line may be a terminally differentiated cardiomyocyte.
The at least one biological cell may be harvested from a mammalian heart or muscle. From example, the stem cell may be a direct muscle cell from any mammalian organism.
The at least one biological cell may be a plurality of cardiomyocytes cells arranged in a monolayer.
The monolayer may be deposited on the biocompatible surface.
The biocompatible surface may be a piezoelectric nano-layer. The piezoelectric layer may be a polymer based surface.
The piezoelectric layer may be a transducer converting from a vibrational and/or mechanical energy to an electrical energy.
The energy harvesting device may further comprise an inlet for adding a chemical or biological solution on the biological cell to increase or decrease the vibrational energy from the biological cell.
The energy harvesting device may further comprise a controller coupled with the device, wherein the controller is configured to transmit the electrical energy into the energy storage medium.
The energy storage medium may be a capacitor.
The energy storage medium may be a battery. The energy storage medium may be an output such as light.
Brief Description of the Preferred Embodiments
Some preferred embodiments of the disclosure will now be described by way of example only and with reference to the accompanying drawings, in which:
Figure 1 illustrates a schematic representation of an energy harvesting device according to one embodiment of the present disclosure; and
Figure 2 illustrates a detailed view of a biocompatible surface and biological cell of the device of Figure 1.
Detailed Description of the Preferred Embodiments
Figure 1 illustrates a schematic representation of an energy harvesting device according to one embodiment of the present disclosure. The device includes a chamber 115 which is coupled with a bio-compatible nano-surface 100. In one example, the biocompatible nano-surface 100 is a piezoelectric nano-device. The piezoelectric surface 100 is a polymer based surface. The device includes biological cells 105 coupled with the piezoelectric surface 100. In one example, the biological cells are generally cardiomyocytes or heart muscle cells. The chamber 115 includes a cell media 110 which is disposed on the cardiomyocytes 105. The cell media 110 can be stem cell media such as cell culture media, human IPS media, XENO-Free and Serum-Free stem cell media.
The device also includes a controller which includes an electrical conductor 120 connecting to an energy storage medium 125. The energy storage medium 125 is a battery or a capacitor.
In one embodiment, the cardiomyocytes 105 are arranged in a monolayer on the piezoelectric nano-surface 100. When the cardiomyocytes 105 generate beats or vibration the mechanical/vibrational energy is transferred to the piezoelectric nanosurface 100. From the piezoelectric nano-surface 100 the mechanical/vibrational energy is converted into an electrical energy, which is transferred to the battery 125 through the conductive wire 120.
Figure 2 illustrates a detailed view of a biocompatible nano-surface and biological cell of the device of Figure 1. In this embodiment, the biocompatible nano-surface 100 has a corrugated shape increasing the surface area. The biological cells 105 are distributed around the corrugated shape so that electricity can be generated from the increased surface area.
It will be appreciated that the invention is not limited to the corrugated shape of Figure 2, other types of shapes for the piezoelectric surface can be contemplated.
Although the disclosure has been described in terms of preferred embodiments as set forth above, it should be understood that these embodiments are illustrative only and that the claims are not limited to those embodiments. Those skilled in the art will be able to make modifications and alternatives in view of the disclosure which are contemplated as falling within the scope of the appended claims. Each feature disclosed or illustrated in the present specification may be incorporated in the disclosure, whether alone or in any appropriate combination with any other feature disclosed or illustrated herein.

Claims (15)

1. An energy harvesting device comprising:
at least one biological cell;
a bio-compatible surface coupled with said at least one biological cell; wherein the bio-compatible surface is configured such that a vibrational and/or mechanical energy from the at least one biological cell is converted to an electrical potential energy for storage in a storage medium.
2. An energy harvesting device according to claim 1, wherein the at least one biological cell comprises at least one stem cell.
3. An energy harvesting device according to claim 1 or 2, wherein at least one biological cell comprises at least one induced pluripotent stem cell (iPSC) line.
4. An energy harvesting device according to claim 3, wherein the induced pluripotent stem cell line is a cardiomyocyte.
5. An energy harvesting device according to claim 1, wherein the at least one biological cell is a heart or muscle stem cell.
6. An energy harvesting device according any preceding claim, wherein the at least one biological cell is a plurality of cardiomyocytes cells arranged in a monolayer.
7. An energy harvesting device according to claim 6, wherein the monolayer is deposited on the biocompatible surface.
8. An energy harvesting device according to any preceding claim, wherein the biocompatible surface is a biocompatible nano-surface.
9. An energy harvesting device according to any preceding claim, wherein the biocompatible surface is a piezoelectric layer.
10. An energy harvesting device according claim 9, wherein the piezoelectric layer is a polymer based surface.
11. An energy harvesting device according claim 10, wherein the piezoelectric layer is a transducer converting from a vibrational and/or mechanical energy to electrical energy.
12. An energy harvesting device according any preceding claim, further comprising an exogenous chemical or biological media to increase or decrease the mechanical/vibrational energy from the biological cell.
13. An energy harvesting device according to any one of claims 8 to 12, further comprising a controller coupled with the device, wherein the controller is configured to transmit the electrical energy through the energy storage medium.
14. An energy harvesting device according to claim 13, wherein the energy storage medium is a capacitor.
15. An energy harvesting device according to claim 13, wherein the energy storage medium is a battery.
GB1717653.8A 2017-10-26 2017-10-26 An energy harvesting device Withdrawn GB2567851A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1717653.8A GB2567851A (en) 2017-10-26 2017-10-26 An energy harvesting device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1717653.8A GB2567851A (en) 2017-10-26 2017-10-26 An energy harvesting device

Publications (2)

Publication Number Publication Date
GB201717653D0 GB201717653D0 (en) 2017-12-13
GB2567851A true GB2567851A (en) 2019-05-01

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090226768A1 (en) * 2008-03-04 2009-09-10 Georgia Tech Research Corporation Muscle-Driven Nanogenerators
US20110107569A1 (en) * 2009-11-10 2011-05-12 Georgia Tech Research Corporation Large-Scale Lateral Nanowire Arrays Nanogenerators
WO2015106282A1 (en) * 2014-01-13 2015-07-16 The Arizona Board Of Regents On Behalf Of The University Of Arizona Materials, devices and systems for piezoelectric energy harvesting and storage

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090226768A1 (en) * 2008-03-04 2009-09-10 Georgia Tech Research Corporation Muscle-Driven Nanogenerators
US20110107569A1 (en) * 2009-11-10 2011-05-12 Georgia Tech Research Corporation Large-Scale Lateral Nanowire Arrays Nanogenerators
WO2015106282A1 (en) * 2014-01-13 2015-07-16 The Arizona Board Of Regents On Behalf Of The University Of Arizona Materials, devices and systems for piezoelectric energy harvesting and storage

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Publication number Publication date
GB201717653D0 (en) 2017-12-13

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