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GB2563752B - Monitoring ion mobility spectrometry environment for improved collision cross section accuracy and precision - Google Patents

Monitoring ion mobility spectrometry environment for improved collision cross section accuracy and precision

Info

Publication number
GB2563752B
GB2563752B GB1812676.3A GB201812676A GB2563752B GB 2563752 B GB2563752 B GB 2563752B GB 201812676 A GB201812676 A GB 201812676A GB 2563752 B GB2563752 B GB 2563752B
Authority
GB
United Kingdom
Prior art keywords
precision
environment
ion mobility
mobility spectrometry
collision cross
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1812676.3A
Other versions
GB2563752A (en
GB201812676D0 (en
Inventor
Derek Pringle Steven
Salarzaei Farnoush
Tomczyk Nick
Lee Wildgoose Jason
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Publication of GB201812676D0 publication Critical patent/GB201812676D0/en
Publication of GB2563752A publication Critical patent/GB2563752A/en
Application granted granted Critical
Publication of GB2563752B publication Critical patent/GB2563752B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622Ion mobility spectrometry
    • G01N27/623Ion mobility spectrometry combined with mass spectrometry
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/0009Calibration of the apparatus
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/004Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/24Vacuum systems, e.g. maintaining desired pressures

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
GB1812676.3A 2014-06-11 2015-06-10 Monitoring ion mobility spectrometry environment for improved collision cross section accuracy and precision Active GB2563752B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1410369.1A GB201410369D0 (en) 2014-06-11 2014-06-11 Monitoring IMS environment for improved CCS accuracy and precision
GBGB1414753.2A GB201414753D0 (en) 2014-06-11 2014-08-20 Monitoring IMS enviroment for improved CCS accuracy and pecision
GB1510080.3A GB2531385B (en) 2014-06-11 2015-06-10 Monitoring ion mobility spectrometry environment for improved collision cross section accuracy and precision

Publications (3)

Publication Number Publication Date
GB201812676D0 GB201812676D0 (en) 2018-09-19
GB2563752A GB2563752A (en) 2018-12-26
GB2563752B true GB2563752B (en) 2019-04-10

Family

ID=51267045

Family Applications (4)

Application Number Title Priority Date Filing Date
GBGB1410369.1A Ceased GB201410369D0 (en) 2014-06-11 2014-06-11 Monitoring IMS environment for improved CCS accuracy and precision
GBGB1414753.2A Ceased GB201414753D0 (en) 2014-06-11 2014-08-20 Monitoring IMS enviroment for improved CCS accuracy and pecision
GB1812676.3A Active GB2563752B (en) 2014-06-11 2015-06-10 Monitoring ion mobility spectrometry environment for improved collision cross section accuracy and precision
GB1510080.3A Active GB2531385B (en) 2014-06-11 2015-06-10 Monitoring ion mobility spectrometry environment for improved collision cross section accuracy and precision

Family Applications Before (2)

Application Number Title Priority Date Filing Date
GBGB1410369.1A Ceased GB201410369D0 (en) 2014-06-11 2014-06-11 Monitoring IMS environment for improved CCS accuracy and precision
GBGB1414753.2A Ceased GB201414753D0 (en) 2014-06-11 2014-08-20 Monitoring IMS enviroment for improved CCS accuracy and pecision

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1510080.3A Active GB2531385B (en) 2014-06-11 2015-06-10 Monitoring ion mobility spectrometry environment for improved collision cross section accuracy and precision

Country Status (1)

Country Link
GB (4) GB201410369D0 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3286557B1 (en) * 2015-04-23 2021-09-01 Micromass UK Limited Separating ions in an ion trap

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5796099A (en) * 1995-06-07 1998-08-18 Barringer Instruments Ltd. Pressure based calibration correction of an ion mobility spectrometer
US20030116705A1 (en) * 2001-11-30 2003-06-26 Isik Kanik Proton-transfer-reaction/ion-mobility-spectrometer and method of using the same
US20070158543A1 (en) * 2005-10-14 2007-07-12 Washington State University Mass analysis of mobility selected ion populations
WO2010125357A2 (en) * 2009-05-01 2010-11-04 Shimadzu Research Laboratory (Europe) Limited Ion analysis apparatus and method of use
WO2011020034A1 (en) * 2009-08-13 2011-02-17 Sionex Corporation Coupling ion differential mobility based ambient pressure ion pre-filtering and ion focusing for a portable mass spectrometer
US20110183431A1 (en) * 2010-01-28 2011-07-28 MDS Analytical Technologies, a business unit of MDS, Inc. Mass analysis system with low pressure differential mobility spectrometer
US8173959B1 (en) * 2007-07-21 2012-05-08 Implant Sciences Corporation Real-time trace detection by high field and low field ion mobility and mass spectrometry
US20120326023A1 (en) * 2011-06-27 2012-12-27 Department Of Homeland Security ION MOBILITY SPECTROMETER to MASS SPECTROMETER INTERFACE
WO2013080044A2 (en) * 2011-11-17 2013-06-06 Owlstone Limited Sensor apparatus and method for use with gas ionization systems
EP2634556A1 (en) * 2010-10-29 2013-09-04 Atonarp Inc. Sampling apparatus

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552600A (en) * 1995-06-07 1996-09-03 Barringer Research Limited Pressure stabilized ion mobility spectrometer
CA2493526C (en) * 2004-01-22 2010-03-30 Ionalytics Corporation Apparatus and method for controllably affecting the temperature of faims components
EP1920243B1 (en) * 2005-04-29 2015-09-09 DH Technologies Development Pte. Ltd. Compact gas chromatography and ion mobility based sample analysis systems, methods, and devices
WO2008005283A2 (en) * 2006-06-29 2008-01-10 Sionex Corporation Tandem differential mobility spectrometers and mass spectrometer for enhanced analysis
EP2613140A4 (en) * 2010-08-31 2016-12-21 Atonarp Inc DEVICE FOR PREPARING A SAMPLE PROVIDED TO AN ION MOBILITY DETECTOR
US9089279B2 (en) * 2011-12-29 2015-07-28 General Electric Company Ion-based breath analysis system

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5796099A (en) * 1995-06-07 1998-08-18 Barringer Instruments Ltd. Pressure based calibration correction of an ion mobility spectrometer
US20030116705A1 (en) * 2001-11-30 2003-06-26 Isik Kanik Proton-transfer-reaction/ion-mobility-spectrometer and method of using the same
US20070158543A1 (en) * 2005-10-14 2007-07-12 Washington State University Mass analysis of mobility selected ion populations
US8173959B1 (en) * 2007-07-21 2012-05-08 Implant Sciences Corporation Real-time trace detection by high field and low field ion mobility and mass spectrometry
WO2010125357A2 (en) * 2009-05-01 2010-11-04 Shimadzu Research Laboratory (Europe) Limited Ion analysis apparatus and method of use
WO2011020034A1 (en) * 2009-08-13 2011-02-17 Sionex Corporation Coupling ion differential mobility based ambient pressure ion pre-filtering and ion focusing for a portable mass spectrometer
US20110183431A1 (en) * 2010-01-28 2011-07-28 MDS Analytical Technologies, a business unit of MDS, Inc. Mass analysis system with low pressure differential mobility spectrometer
EP2634556A1 (en) * 2010-10-29 2013-09-04 Atonarp Inc. Sampling apparatus
US20120326023A1 (en) * 2011-06-27 2012-12-27 Department Of Homeland Security ION MOBILITY SPECTROMETER to MASS SPECTROMETER INTERFACE
WO2013080044A2 (en) * 2011-11-17 2013-06-06 Owlstone Limited Sensor apparatus and method for use with gas ionization systems

Also Published As

Publication number Publication date
GB2531385A (en) 2016-04-20
GB2531385B (en) 2019-04-10
GB201510080D0 (en) 2015-07-22
GB2563752A (en) 2018-12-26
GB201410369D0 (en) 2014-07-23
GB201414753D0 (en) 2014-10-01
GB201812676D0 (en) 2018-09-19

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