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GB2496805B - Compounds for photodynamic therapy - Google Patents

Compounds for photodynamic therapy

Info

Publication number
GB2496805B
GB2496805B GB1303099.4A GB201303099A GB2496805B GB 2496805 B GB2496805 B GB 2496805B GB 201303099 A GB201303099 A GB 201303099A GB 2496805 B GB2496805 B GB 2496805B
Authority
GB
United Kingdom
Prior art keywords
compounds
photodynamic therapy
photodynamic
therapy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB1303099.4A
Other versions
GB201303099D0 (en
GB2496805A (en
Inventor
Bandyopadyay Susmita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
REPUBLIC POLYTECHNIC
Original Assignee
REPUBLIC POLYTECHNIC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by REPUBLIC POLYTECHNIC filed Critical REPUBLIC POLYTECHNIC
Publication of GB201303099D0 publication Critical patent/GB201303099D0/en
Publication of GB2496805A publication Critical patent/GB2496805A/en
Application granted granted Critical
Publication of GB2496805B publication Critical patent/GB2496805B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/22—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing two or more pyridine rings directly linked together, e.g. bipyridyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/08—Copper compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB1303099.4A 2010-07-21 2011-07-21 Compounds for photodynamic therapy Expired - Fee Related GB2496805B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1012217.4A GB201012217D0 (en) 2010-07-21 2010-07-21 Compounds for photodynamic therapy
PCT/SG2011/000261 WO2012011875A1 (en) 2010-07-21 2011-07-21 Compounds for photodynamic therapy

Publications (3)

Publication Number Publication Date
GB201303099D0 GB201303099D0 (en) 2013-04-10
GB2496805A GB2496805A (en) 2013-05-22
GB2496805B true GB2496805B (en) 2018-12-26

Family

ID=42752551

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB1012217.4A Ceased GB201012217D0 (en) 2010-07-21 2010-07-21 Compounds for photodynamic therapy
GB1303099.4A Expired - Fee Related GB2496805B (en) 2010-07-21 2011-07-21 Compounds for photodynamic therapy

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB1012217.4A Ceased GB201012217D0 (en) 2010-07-21 2010-07-21 Compounds for photodynamic therapy

Country Status (5)

Country Link
AU (1) AU2011280265B2 (en)
CA (1) CA2809405C (en)
GB (2) GB201012217D0 (en)
SG (1) SG187919A1 (en)
WO (1) WO2012011875A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009311239B2 (en) 2008-11-07 2012-11-15 Klox Technologies Inc. Oxidatitive photoactivated skin rejeuvenation composition comprising hyaluronic acid, glucosamine, or allantoin
SG10201700310PA (en) 2009-07-17 2017-03-30 Klox Technologies Inc Combination of an oxidant, a photosensitizer and a wound healing agent for oral disinfection and treatment of oral disease
US11116841B2 (en) 2012-04-20 2021-09-14 Klox Technologies Inc. Biophotonic compositions, kits and methods
US20130281913A1 (en) 2012-04-20 2013-10-24 Klox Technologies Inc. Biophotonic compositions and methods for providing biophotonic treatment
CN102911191B (en) * 2012-10-26 2015-05-06 商丘师范学院 Preparation method for ethanol 2-hydroxyl naphthaldehyde thiosemicarbazone o-phenanthroline metal complex
US20140276354A1 (en) * 2013-03-14 2014-09-18 Klox Technologies Inc. Biophotonic materials and uses thereof
HK1219890A1 (en) 2013-07-03 2017-04-21 广东科洛克生物医药集团有限公司 Biophotonic compositions comprising a chromophore and a gelling agent for treating wounds
KR20160140716A (en) 2014-04-01 2016-12-07 클록스 테크놀로지스 인크. Tissue filler compositions and methods of use
RU2017117187A (en) 2014-10-31 2018-11-30 Клокс Текнолоджиз Инк. PHOTO-ACTIVATED FIBERS AND WOVEN MATERIALS
CN107417708B (en) * 2017-08-04 2019-04-09 广西师范大学 A kind of water-soluble copper (II) complex and its synthesis method and application
CN108218924A (en) * 2018-03-15 2018-06-29 陕西理工大学 A kind of Schiff base complex of ruthenium and preparation method and application
CN109243747B (en) * 2018-11-22 2020-05-22 北京石油化工学院 A kind of preparation method of dysprosium single ion magnetic material
CN110305146B (en) * 2019-07-17 2022-03-11 山西农业大学 Chain-shaped Schiff base copper complex and preparation method and application thereof
IL312692A (en) 2021-11-16 2024-07-01 Genentech Inc Methods and compositions for treating systemic lupus erythematosus (sle) with mosunetuzumab
CN114656490B (en) * 2022-03-23 2023-11-28 陕西理工大学 Preparation method and application of copper-zinc heterobinuclear Schiff base complex
CN115974935A (en) * 2023-01-17 2023-04-18 广西师范大学 Ring metal organic rhodium complex of oxidized isoaporphine alkaloid and bipyridyl derivative and synthetic method and application thereof
CN120098048B (en) * 2025-03-07 2025-12-02 中山大学 An osmium complex, its preparation method and application

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
Acta Chemica Scandanavica, vol. 23, 1969, pages 1503-1513, DAHL et al. "Studies of chelates with heterocyclic ligands" *
Bulletin of the Chemical Society of Japan, vol. 65, 1992, 1603-1607, OHKUBO et al. "Syntheses and magnetic properties of imidazolate-bridged binuclear copper (II) complexes: Effect of bridging mode upon magnetic interaction" *
Chinese Journal of Inorganic Chemistry, vol. 26, No. 12, 2010, pages 221-2226, QIU et al. "Synthesis, structure and electrochemical properties of ternary copper (II) complex of ONN-donor Schiff base and 2,2'-bipyridine" *
Dalton Transactions, vol. 39, 2010, pages 2027-2035, DE SOUZA et al. "DNA Photonuclease activity of four new copper (II) complexes under UV and red light:Theoretical/Experimental correlatios with active species generation". *
Inorganic Chemistry, vol. 19, 1980, pages 2604-2608, GRZYBOWSKI et al. "Binuclear metal complexes, 2, A uniquie mononuclear copper (I) complex with a potentially binucleating Schiff base ligand" *
Inorganic Chemistry, vol. 47, 2008, 3119-3127, HINDO et al. "Synthesis, redox and amphiphilic properties responsive salycilaldimine-copper (II) soft materials" *
Inorganica Chimica Acta, vol. 12, 1975, pages 109-112, YAMANOUCHI et al. "Metal complexes with Schiff bases obtained from salicaldehyde derivatives and 2-aminoethylpyridine" *
Journal of the American Chemical Society, vol. 127, 2005, pages 11037-11046, JONES et al. "Discovery and optimisation of new chromium catalysts for ethylene oligomerisation and polymerisation aided by high-throughput screening" *

Also Published As

Publication number Publication date
WO2012011875A1 (en) 2012-01-26
GB201303099D0 (en) 2013-04-10
SG187919A1 (en) 2013-03-28
CA2809405C (en) 2018-06-12
AU2011280265A1 (en) 2013-03-14
CA2809405A1 (en) 2012-01-26
GB2496805A (en) 2013-05-22
GB201012217D0 (en) 2010-09-08
AU2011280265B2 (en) 2015-03-05

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20190326