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GB2494580A - Method for diagnosing lung cancer - Google Patents

Method for diagnosing lung cancer Download PDF

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Publication number
GB2494580A
GB2494580A GB1222576.9A GB201222576A GB2494580A GB 2494580 A GB2494580 A GB 2494580A GB 201222576 A GB201222576 A GB 201222576A GB 2494580 A GB2494580 A GB 2494580A
Authority
GB
United Kingdom
Prior art keywords
lung cancer
subject
methods
diagnosing lung
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB1222576.9A
Other versions
GB2494580B (en
GB201222576D0 (en
Inventor
Paul David Lewis
Luis Alejandro Jose Mur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aberystwyth University
Swansea University
Original Assignee
Aberystwyth University
Swansea University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aberystwyth University, Swansea University filed Critical Aberystwyth University
Publication of GB201222576D0 publication Critical patent/GB201222576D0/en
Publication of GB2494580A publication Critical patent/GB2494580A/en
Application granted granted Critical
Publication of GB2494580B publication Critical patent/GB2494580B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N33/5752—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N2021/3595—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using FTIR

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Provided are methods for diagnosing lung cancer in a subject or for identifying a subject at risk of developing lung cancer, the method comprising performing FTIR spectral analysis of a sputum sample obtained from the subject and comparing the spectrum produced from the sample with an FTIR spectrum from a normal control. Also provided are methods for detecting early and late stage cancer, methods for monitoring the progression of lung cancer in a subject and kits for use in the described methods.
GB1222576.9A 2010-07-02 2011-07-01 Method for diagnosing lung cancer Expired - Fee Related GB2494580B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1011171.4A GB201011171D0 (en) 2010-07-02 2010-07-02 Method for diagnosing lung cancer
PCT/GB2011/000997 WO2012001370A1 (en) 2010-07-02 2011-07-01 Method for diagnosing lung cancer

Publications (3)

Publication Number Publication Date
GB201222576D0 GB201222576D0 (en) 2013-01-30
GB2494580A true GB2494580A (en) 2013-03-13
GB2494580B GB2494580B (en) 2017-05-10

Family

ID=42669106

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB1011171.4A Ceased GB201011171D0 (en) 2010-07-02 2010-07-02 Method for diagnosing lung cancer
GB1222576.9A Expired - Fee Related GB2494580B (en) 2010-07-02 2011-07-01 Method for diagnosing lung cancer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB1011171.4A Ceased GB201011171D0 (en) 2010-07-02 2010-07-02 Method for diagnosing lung cancer

Country Status (2)

Country Link
GB (2) GB201011171D0 (en)
WO (1) WO2012001370A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103760127B (en) * 2013-12-31 2016-08-17 浙江省林业科学研究院 The infrared identification method of true and false Radix Linderae tuber
GB201401055D0 (en) * 2014-01-22 2014-03-05 Univ Swansea Method for diagnosing lung diseases
WO2016097996A1 (en) 2014-12-16 2016-06-23 Ecole Polytechnique Federale De Lausanne (Epfl) Use of fourier transform infrared spectroscopy analysis of extracellular vesicles isolated from body fluids for diagnosing, prognosing and monitoring pathophysiological states and method therfor
US11422084B2 (en) * 2017-12-06 2022-08-23 California Institute Of Technology System for analyzing a test sample and method therefor
GB201806002D0 (en) * 2018-04-11 2018-05-23 Univ Liverpool Methods of spectroscopic analysis
JP7596378B2 (en) * 2019-11-15 2024-12-09 シエラ メディカル リミテッド Methods for detecting lung cancer
GB202017340D0 (en) * 2020-11-02 2020-12-16 Univ Swansea Lung cancer diagnostic
GB2640556A (en) * 2024-04-24 2025-10-29 Aberystwyth Univ Biomarkers for lung cancer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100075367A1 (en) * 2003-07-22 2010-03-25 Vadivel Masilamani Lung cancer detection by optical analysis of body fluids

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100075367A1 (en) * 2003-07-22 2010-03-25 Vadivel Masilamani Lung cancer detection by optical analysis of body fluids

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BOSCH, A. et al; "Fourier transform infrared spectroscopy for rapid identification of nonfermenting gram-negative bacteriaisolated from sputum samples from cystic fibrosis patients", JOURNAL OF CLINICAL MICROBIOLOGY, vol 46, no 8, (2008-08-01), pp2535-2546 *
LEWIS, P.D. et al; "Evaluation of FTIR spectroscopy as a diagnostic tool for lung cancer using sputum", BMC CANCER, vol 10, no 1, (2010-11-23), p640 *
WANG, H et al; "Microscopic FTIR studies of lung cancer cells in pleural fluid", SCIENCE OF THE TOTAL ENVIRONMENT, Vol 204, No 3, (1997-10-01), pp283-287 *
WHITEMAN, S.C. et al; "FTIR spectroscopic analysis of sputum:Preliminary findings on a potential novel diagnostic marker for COPD", THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE, Vol 2, no 1, (2008-01-01), pp23-31 *
YANO, K. et al; "Direct measurement of human lung cancerous and noncancerous tissues by fourier transform infrared microscopy", ANALYTICAL BIOCHEMISTRY, Vol 287, no 2, (2000-01-01), pp218-225 *

Also Published As

Publication number Publication date
GB2494580B (en) 2017-05-10
WO2012001370A1 (en) 2012-01-05
GB201222576D0 (en) 2013-01-30
GB201011171D0 (en) 2010-08-18

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20210701