GB2440050B - Linear high-throughput proteomics - Google Patents
Linear high-throughput proteomicsInfo
- Publication number
- GB2440050B GB2440050B GB0713615A GB0713615A GB2440050B GB 2440050 B GB2440050 B GB 2440050B GB 0713615 A GB0713615 A GB 0713615A GB 0713615 A GB0713615 A GB 0713615A GB 2440050 B GB2440050 B GB 2440050B
- Authority
- GB
- United Kingdom
- Prior art keywords
- linear high
- throughput proteomics
- proteomics
- throughput
- linear
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B1/00—Devices without movable or flexible elements, e.g. microcapillary devices
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
- G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
- G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Optics & Photonics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Computer Hardware Design (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/484,912 US7550259B2 (en) | 2006-07-12 | 2006-07-12 | Linear high-throughput proteomics |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB0713615D0 GB0713615D0 (en) | 2007-08-22 |
| GB2440050A GB2440050A (en) | 2008-01-16 |
| GB2440050B true GB2440050B (en) | 2011-10-12 |
Family
ID=38461525
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0713615A Expired - Fee Related GB2440050B (en) | 2006-07-12 | 2007-07-12 | Linear high-throughput proteomics |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US7550259B2 (en) |
| DE (1) | DE102007032258A1 (en) |
| GB (1) | GB2440050B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12429405B2 (en) | 2018-03-13 | 2025-09-30 | Amgen Inc. | Sequential digestion of polypeptides for mass spectrometric analysis |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3425405B1 (en) * | 2017-07-06 | 2021-03-10 | Thermo Finnigan LLC | Methods of mass spectrometry quantitation using cleavable isobaric tags and neutral loss fragmentation |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6569383B1 (en) * | 2000-03-11 | 2003-05-27 | Intrinsic Bioprobes, Inc. | Bioactive chip mass spectrometry |
| WO2003044221A1 (en) * | 2001-10-19 | 2003-05-30 | West Virginia University Research Corporation | Microfluidic system for proteome analysis |
| EP1447136A1 (en) * | 2003-02-12 | 2004-08-18 | Agilent Technologies, Inc. | PAEK-based microfluidic device |
| US20060192107A1 (en) * | 2004-10-07 | 2006-08-31 | Devoe Donald L | Methods and apparatus for porous membrane electrospray and multiplexed coupling of microfluidic systems with mass spectrometry |
| US7128876B2 (en) * | 2001-07-17 | 2006-10-31 | Agilent Technologies, Inc. | Microdevice and method for component separation in a fluid |
-
2006
- 2006-07-12 US US11/484,912 patent/US7550259B2/en active Active
-
2007
- 2007-07-11 DE DE102007032258A patent/DE102007032258A1/en not_active Withdrawn
- 2007-07-12 GB GB0713615A patent/GB2440050B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6569383B1 (en) * | 2000-03-11 | 2003-05-27 | Intrinsic Bioprobes, Inc. | Bioactive chip mass spectrometry |
| US7128876B2 (en) * | 2001-07-17 | 2006-10-31 | Agilent Technologies, Inc. | Microdevice and method for component separation in a fluid |
| WO2003044221A1 (en) * | 2001-10-19 | 2003-05-30 | West Virginia University Research Corporation | Microfluidic system for proteome analysis |
| EP1447136A1 (en) * | 2003-02-12 | 2004-08-18 | Agilent Technologies, Inc. | PAEK-based microfluidic device |
| US20060192107A1 (en) * | 2004-10-07 | 2006-08-31 | Devoe Donald L | Methods and apparatus for porous membrane electrospray and multiplexed coupling of microfluidic systems with mass spectrometry |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12429405B2 (en) | 2018-03-13 | 2025-09-30 | Amgen Inc. | Sequential digestion of polypeptides for mass spectrometric analysis |
Also Published As
| Publication number | Publication date |
|---|---|
| DE102007032258A1 (en) | 2008-01-31 |
| US7550259B2 (en) | 2009-06-23 |
| US20080014603A1 (en) | 2008-01-17 |
| GB2440050A (en) | 2008-01-16 |
| GB0713615D0 (en) | 2007-08-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20190712 |