[go: up one dir, main page]

GB2307028A - Access valve devices, their use in separation apparatus, and corresponding methods - Google Patents

Access valve devices, their use in separation apparatus, and corresponding methods

Info

Publication number
GB2307028A
GB2307028A GB9701312A GB9701312A GB2307028A GB 2307028 A GB2307028 A GB 2307028A GB 9701312 A GB9701312 A GB 9701312A GB 9701312 A GB9701312 A GB 9701312A GB 2307028 A GB2307028 A GB 2307028A
Authority
GB
United Kingdom
Prior art keywords
probe
valve
column
conduit
conduits
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB9701312A
Other versions
GB2307028B (en
GB9701312D0 (en
Inventor
John Davis
Martin John Hofmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pall Euroflow Ltd
Original Assignee
Euroflow UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9419888A external-priority patent/GB9419888D0/en
Application filed by Euroflow UK Ltd filed Critical Euroflow UK Ltd
Priority to GB9701312A priority Critical patent/GB2307028B/en
Publication of GB9701312D0 publication Critical patent/GB9701312D0/en
Publication of GB2307028A publication Critical patent/GB2307028A/en
Application granted granted Critical
Publication of GB2307028B publication Critical patent/GB2307028B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K1/00—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces
    • F16K1/32—Details
    • F16K1/34—Cutting-off parts, e.g. valve members, seats
    • F16K1/44—Details of seats or valve members of double-seat valves
    • F16K1/443—Details of seats or valve members of double-seat valves the seats being in series
    • F16K1/446—Details of seats or valve members of double-seat valves the seats being in series with additional cleaning or venting means between the two seats
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
    • B01D15/206—Packing or coating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/22—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the construction of the column
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/56—Packing methods or coating methods
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/56—Packing methods or coating methods
    • G01N2030/562—Packing methods or coating methods packing
    • G01N2030/565—Packing methods or coating methods packing slurry packing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6017—Fluid distributors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Multiple-Way Valves (AREA)

Abstract

An access valve suitable for controlling fluid flow into and out of a chromatography column has a central axially movable probe with a head (71) acting as a spool valve in a barrel (6). Axial movement of the probe adjusts the valve between a fully open condition, in which both a first conduit (73) extending through the probe and a second conduit (51) defined around the probe are open to the column interior, a partly open condition in which a second sealing land (76) on the probe closes the second conduit (51), and a fully closed position in which both conduits are closed. The three positions are useful for packing and unpacking chromatography media into and from the column. In the closed condition of the valve, the first and second conduits (73, 51) communicate with one another so that the valve interior can be cleaned while the column is operating.
GB9701312A 1994-10-03 1995-10-03 Access valve devices, their use in chromatography apparatus, and corresponding thods Expired - Lifetime GB2307028B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB9701312A GB2307028B (en) 1994-10-03 1995-10-03 Access valve devices, their use in chromatography apparatus, and corresponding thods

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9419888A GB9419888D0 (en) 1994-10-03 1994-10-03 Apparatus and techiques for separation
GB9701312A GB2307028B (en) 1994-10-03 1995-10-03 Access valve devices, their use in chromatography apparatus, and corresponding thods
PCT/GB1995/002338 WO1996010451A1 (en) 1994-10-03 1995-10-03 Access valve devices, their use in separation apparatus, and corresponding methods

Publications (3)

Publication Number Publication Date
GB9701312D0 GB9701312D0 (en) 1997-03-12
GB2307028A true GB2307028A (en) 1997-05-14
GB2307028B GB2307028B (en) 1997-09-17

Family

ID=26305727

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9701312A Expired - Lifetime GB2307028B (en) 1994-10-03 1995-10-03 Access valve devices, their use in chromatography apparatus, and corresponding thods

Country Status (1)

Country Link
GB (1) GB2307028B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2344543A (en) * 1998-12-10 2000-06-14 Millipore Corp Chromatography column system and method for packing a chromatography column
US6524484B2 (en) 1994-10-03 2003-02-25 Amersham Pharmacia Biotech Ab Access valve devices, their use in separation apparatus, and corresponding methods

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2379005A1 (en) * 1977-01-29 1978-08-25 Tuchenhagen Otto DUCT VALVE WITH LEAK CONTROL AND CLEANING OF THE LEAK COLLECTOR
NL167338C (en) * 1969-06-26 1981-12-16 Tetra Pak Int SHIFT VALVE FOR CONNECTING A PIPELINE WITH A FIRST MEDIUM PIPE AND A SECOND MEDIUM PIPE.
EP0059857A1 (en) * 1981-02-27 1982-09-15 OTTO TUCHENHAGEN GmbH & Co. KG Cleanable valve for taking samples
GB2258415A (en) * 1991-08-08 1993-02-10 Chromaflow Inc Apparatus and method for charging and discharging of chromatography column bed

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724074A (en) * 1985-10-07 1988-02-09 Parker Hannifin Corporation Self-venting drain assembly

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL167338C (en) * 1969-06-26 1981-12-16 Tetra Pak Int SHIFT VALVE FOR CONNECTING A PIPELINE WITH A FIRST MEDIUM PIPE AND A SECOND MEDIUM PIPE.
FR2379005A1 (en) * 1977-01-29 1978-08-25 Tuchenhagen Otto DUCT VALVE WITH LEAK CONTROL AND CLEANING OF THE LEAK COLLECTOR
EP0059857A1 (en) * 1981-02-27 1982-09-15 OTTO TUCHENHAGEN GmbH & Co. KG Cleanable valve for taking samples
GB2258415A (en) * 1991-08-08 1993-02-10 Chromaflow Inc Apparatus and method for charging and discharging of chromatography column bed

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6524484B2 (en) 1994-10-03 2003-02-25 Amersham Pharmacia Biotech Ab Access valve devices, their use in separation apparatus, and corresponding methods
US6719899B2 (en) 1994-10-03 2004-04-13 Amersham Biosciences Ab Access valve devices, their use in separation apparatus, and corresponding methods
GB2344543A (en) * 1998-12-10 2000-06-14 Millipore Corp Chromatography column system and method for packing a chromatography column
GB2344543B (en) * 1998-12-10 2002-11-27 Millipore Corp Chromatography column system and method of packing a chromatography system

Also Published As

Publication number Publication date
GB2307028B (en) 1997-09-17
GB9701312D0 (en) 1997-03-12

Similar Documents

Publication Publication Date Title
ZA958290B (en) Access valve devices their use in separation apparatus and corresponding methods
AU7064591A (en) Dispenser for media
BR9916233A (en) Container with pressure control device, designed to maintain a preset pressure in the substantially constant container, and method to make a container ready for the distribution of a fluid at a substantially constant pressure
NO860923L (en) BALL VALVE.
IE832809L (en) Valve
CA2199301A1 (en) Dual bore annulus access valve
EP0200563A3 (en) Process line valve
GB2307028A (en) Access valve devices, their use in separation apparatus, and corresponding methods
KR870009169A (en) Fluid control valve
DK276187A (en) SHUT-OFF VALVE
EP1018614A3 (en) Plug valve
JPS5612065A (en) Hydraulic engine
JPS563356A (en) Open and close valve for fluid conduit pipe
DK543384A (en) CONTROL VALVE
GB9522187D0 (en) Dual concentric poppet valves for maintaining substantially constant the ratio of two fluid flows over an operating range of valve opening
AU2338600A (en) Device of a tool spindle
CA2272288A1 (en) Method and sealing valve unit for controlling fluid flow through a passage
GB2332939B (en) Means for testing a fluid valve and method therefor
GB2265966A (en) Flow control valve
CN2095982U (en) Three-way rotary valve
FR2734041B1 (en) VALVE ARRANGEMENT FOR A GAS BOTTLE
KR890003511A (en) Injection device of the reactor
JPS5715176A (en) Valve
SE8303881D0 (en) VALVE
JPS5666562A (en) Axial flow sealing device for sealing high fluid pressure

Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
727 Application made for amendment of specification (sect. 27/1977)
775B Specification amended (sect. 75/1977)
PE20 Patent expired after termination of 20 years

Expiry date: 20151002