GB2384705A - Cosmetic composition comprising gellan gum and carrageenan - Google Patents
Cosmetic composition comprising gellan gum and carrageenan Download PDFInfo
- Publication number
- GB2384705A GB2384705A GB0200204A GB0200204A GB2384705A GB 2384705 A GB2384705 A GB 2384705A GB 0200204 A GB0200204 A GB 0200204A GB 0200204 A GB0200204 A GB 0200204A GB 2384705 A GB2384705 A GB 2384705A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cosmetic composition
- produce
- carrageenan
- gel
- gellan gum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002537 cosmetic Substances 0.000 title claims abstract description 147
- 239000000203 mixture Substances 0.000 title claims abstract description 122
- 229920002148 Gellan gum Polymers 0.000 title claims abstract description 49
- 235000010418 carrageenan Nutrition 0.000 title claims abstract description 49
- 239000000679 carrageenan Substances 0.000 title claims abstract description 49
- 229920001525 carrageenan Polymers 0.000 title claims abstract description 49
- 229940113118 carrageenan Drugs 0.000 title claims abstract description 49
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 title claims abstract description 49
- 235000010492 gellan gum Nutrition 0.000 title claims abstract description 48
- 239000000216 gellan gum Substances 0.000 title claims abstract description 48
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 32
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 32
- 235000011187 glycerol Nutrition 0.000 claims abstract description 16
- 239000003352 sequestering agent Substances 0.000 claims abstract description 15
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims abstract description 13
- 239000000600 sorbitol Substances 0.000 claims abstract description 13
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims abstract description 9
- 150000001875 compounds Chemical class 0.000 claims abstract description 9
- 150000005846 sugar alcohols Polymers 0.000 claims abstract description 8
- 238000004519 manufacturing process Methods 0.000 claims abstract description 7
- 239000000839 emulsion Substances 0.000 claims abstract description 6
- 238000000034 method Methods 0.000 claims description 98
- 239000000047 product Substances 0.000 claims description 38
- 239000000126 substance Substances 0.000 claims description 22
- 238000011049 filling Methods 0.000 claims description 19
- 239000004480 active ingredient Substances 0.000 claims description 16
- 239000012467 final product Substances 0.000 claims description 14
- 230000003472 neutralizing effect Effects 0.000 claims description 7
- 239000012530 fluid Substances 0.000 claims 12
- 238000012545 processing Methods 0.000 abstract description 2
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000499 gel Substances 0.000 description 34
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 14
- 239000004615 ingredient Substances 0.000 description 12
- 239000003921 oil Substances 0.000 description 12
- 235000019198 oils Nutrition 0.000 description 12
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 9
- 235000013305 food Nutrition 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 5
- 239000003755 preservative agent Substances 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 239000006172 buffering agent Substances 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 4
- 230000002335 preservative effect Effects 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- 241000208983 Arnica Species 0.000 description 3
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 230000003139 buffering effect Effects 0.000 description 3
- 229910001424 calcium ion Inorganic materials 0.000 description 3
- 235000020708 ginger extract Nutrition 0.000 description 3
- 229940002508 ginger extract Drugs 0.000 description 3
- 239000001525 mentha piperita l. herb oil Substances 0.000 description 3
- 235000019477 peppermint oil Nutrition 0.000 description 3
- 239000001509 sodium citrate Substances 0.000 description 3
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 3
- 229940038773 trisodium citrate Drugs 0.000 description 3
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 description 2
- 241001474374 Blennius Species 0.000 description 2
- 229920002125 Sokalan® Polymers 0.000 description 2
- 239000000551 dentifrice Substances 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- 239000002075 main ingredient Substances 0.000 description 2
- -1 perfumery Substances 0.000 description 2
- 239000004302 potassium sorbate Substances 0.000 description 2
- 235000010241 potassium sorbate Nutrition 0.000 description 2
- 229940069338 potassium sorbate Drugs 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 2
- 235000010234 sodium benzoate Nutrition 0.000 description 2
- 239000004299 sodium benzoate Substances 0.000 description 2
- 238000003892 spreading Methods 0.000 description 2
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 description 1
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 241001237961 Amanita rubescens Species 0.000 description 1
- 244000144725 Amygdalus communis Species 0.000 description 1
- 235000011437 Amygdalus communis Nutrition 0.000 description 1
- 241000416162 Astragalus gummifer Species 0.000 description 1
- 240000008886 Ceratonia siliqua Species 0.000 description 1
- 235000013912 Ceratonia siliqua Nutrition 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 244000020551 Helianthus annuus Species 0.000 description 1
- 244000062730 Melissa officinalis Species 0.000 description 1
- 235000010654 Melissa officinalis Nutrition 0.000 description 1
- 240000007817 Olea europaea Species 0.000 description 1
- 244000000231 Sesamum indicum Species 0.000 description 1
- 241000790234 Sphingomonas elodea Species 0.000 description 1
- 235000019486 Sunflower oil Nutrition 0.000 description 1
- 229920001615 Tragacanth Polymers 0.000 description 1
- ZNOZWUKQPJXOIG-XSBHQQIPSA-L [(2r,3s,4r,5r,6s)-6-[[(1r,3s,4r,5r,8s)-3,4-dihydroxy-2,6-dioxabicyclo[3.2.1]octan-8-yl]oxy]-4-[[(1r,3r,4r,5r,8s)-8-[(2s,3r,4r,5r,6r)-3,4-dihydroxy-6-(hydroxymethyl)-5-sulfonatooxyoxan-2-yl]oxy-4-hydroxy-2,6-dioxabicyclo[3.2.1]octan-3-yl]oxy]-5-hydroxy-2-( Chemical group O[C@@H]1[C@@H](O)[C@@H](OS([O-])(=O)=O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H]2OC[C@H]1O[C@H](O[C@H]1[C@H]([C@@H](CO)O[C@@H](O[C@@H]3[C@@H]4OC[C@H]3O[C@H](O)[C@@H]4O)[C@@H]1O)OS([O-])(=O)=O)[C@@H]2O ZNOZWUKQPJXOIG-XSBHQQIPSA-L 0.000 description 1
- 125000002252 acyl group Chemical group 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 229940072056 alginate Drugs 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 230000001166 anti-perspirative effect Effects 0.000 description 1
- 239000003213 antiperspirant Substances 0.000 description 1
- 238000000222 aromatherapy Methods 0.000 description 1
- 235000021302 avocado oil Nutrition 0.000 description 1
- 239000008163 avocado oil Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229960001631 carbomer Drugs 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 239000002781 deodorant agent Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 230000009969 flowable effect Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003349 gelling agent Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 239000013067 intermediate product Substances 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 239000000865 liniment Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 239000003002 pH adjusting agent Substances 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000009991 scouring Methods 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9717—Rhodophycota or Rhodophyta [red algae], e.g. Porphyra
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/594—Mixtures of polymers
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
Abstract
A method of manufacturing a cosmetic composition comprises use of gellan gum and carrageenan. "Cosmetic" is widely defined to include personal care and hygiene, for the skin, hair and mouth. There are mentioned: use of a structuring agent to reduce or eliminate brittleness, e.g. chosen from polyhydric alcohols, glycerin, sorbitol and glycolic compounds; use of a sequestering agent; pH control; elevated temperature processing; intermediates; bases; a clear gel; a clear gel containing suspended bubbles of oil; an emulsion; a cosmetic composition which, when applied to the body, can produce an artificial skin thereon.
Description
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TITLE Cosmetic and Related Compositions
FIELD OF THE INVENTION
This invention relates to cosmetic compositions, bases for use in making these, and methods of making the same, more particularly involving use of a gel. The term "gel" used herein, unless otherwise stated, refers to cosmetic industry terminology, which is slightly different from food industry terminology, e. g. in that cosmetic gels are slightly flowable.
BACKGROUND
A number of cosmetics are required in gel form. Previous gel cosmetics have been synthetic, using carbomer gums, but there is a demand for natural cosmetics which would extend to natural gel cosmetics. To date, there has not been any successful natural gel cosmetic because the formulations tried have not had the right structure to be cosmetically acceptable. They are too brittle or sticky or slippery, or do not absorb well into the skin or hair. The required properties are well-known and have been readily obtained with synthetic gels. After extensive research, the inventor has discovered a natural gel composition which is able to be made cosmetically acceptable.
THE INVENTION
The inventor perceives that gel form cosmetics made from natural ingredients rather than synthetic ones would be preferable. He also considers that substances used in the food industry have usually undergone much more rigorous testing than substances used in the cosmetics industry. Thus, suitable substances are more natural and safer when taken from the field of food technology than the often synthetic chemicals used in the cosmetics industry; and they are much more suitable to the
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human body. This is more particularly the case with natural products that have an organic origin, i. e. a natural plant origin in which the use of pesticides can be obviated. This also tends towards an environmentally friendly product. The inventor has looked particularly at that class of cosmetics which involve use of a gel, and related products.
According to one aspect of the invention, there is provided a method of manufacturing a cosmetic composition, characterised in that it comprises use of gellan gum and carrageenan. Both gellan gum and carrageenan are polysaccharides. Gellan gum is produced on a commercial scale by the microbiological fermentation action of the micro-organism sphingomonas elodea. It is available from The NeutraSweet Kelco Company, a division of the Monsanto Company, under their trade name KELCOGEL, and the low acyl form is used in the examples described below, as is usual in the food technology art. Carrageenan is obtained from seaweed, and the carrageenan used in the examples described below is kappa-carrageenan, as is usual in the food technology art; this can be obtained from Honeywell & Stein Limited of Times House, Throwley Way, Sutton SM1 4AF, UK under their trade name GELCARIN. The use of either gellan gum or carrageenan without the other tends to give syneresis, a breaking up of the gel structure so that water comes out of the structure, e. g. together with active ingredients dissolved in the water.
The inventor investigated a huge number of different substances and combinations of substances in trying to produce a cosmetic composition using ingredients from natural sources with properties similar to those obtainable for gel cosmetic compositions made from carbomers. He was aware that various combinations of gellan gum and carrageenan were too brittle, and therefore unable to serve as cosmetic
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compositions, but thought of trying to modify such combinations for the purpose.
Therefore, in embodiments of the invention, the processing (e. g. the proportions of these two components and/or the use of additions) must be chosen with a view to providing a suitably low or zero brittleness in order to be usable as a cosmetic composition.
Other gums than gellan gum, e. g. xanthan, locust bean or tragacanth, have been found not suitable because they produce a cloudy product and/or a wrong feel on the skin. For the same reasons, attempts to replace the carrageenan by an alginate or other seaweed gel have not been found anything like as successful as the carrageenan.
The term"cosmetic"as used herein is not to be understood in any narrow sense but includes use in relation to personal care and hygiene, all for external application to the body (including inside the mouth, e. g. dentifrices), for example: in relation to cleaning, polishing, scouring and abrasive preparations, soaps, perfumery, essential oils, aromatherapy oils, cosmetics, hair lotions, dentifrices, deodorants, anti-perspirants, soothing, sun tan and after sun preparations, toilet preparations, and preparations for the care of the body, skin, nails, hair and mouth, and for use in the bath. It is to be noted that the invention can be applied to medicated preparations, and indeed may be used (e. g. as a base) in non-cosmetic medical applications because of its cosmetically acceptable properties, e. g. its feel when applied to the skin. Examples described below can be made entirely from edible ingredients.
According to another aspect of the invention, there is provided a cosmetic composition characterised in that it comprises gellan gum and carrageenan.
Embodiments of the invention may comprise any one or more of the following features, whether as method or product. The w/w ratio of gellan gum to carrageenan
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is substantially in the range of 1: 1 up to 1: 8, preferably substantially in the range of
1: 2 up to 1: 6, more preferably substantially in the range of 1: 2 up to 1: 3. The gellan gum is used in the proportion of from 0.1 to 0.5 weight per cent of the final product, preferably 0.1 to 0.2%. The carrageenan is used in the proportion of from 0.2 to 1.0 weight per cent of the final product, preferably 0.2 to 0.5%. The method comprises use of a structuring agent to reduce or eliminate brittleness. The method comprises use of a structuring agent to produce a gel structure suitable for cosmetic purposes.
Such structure may provide reduced increased water-holding. Apart from its cosmetic suitability when applied to the body (on the skin or hair), the reduced or zero brittleness feature makes for easy pumping from a dispenser by the consumer in order to apply it. The structuring agent comprises one or more substances chosen from the group comprising polyhydric alcohols and glycerin, or from the group comprising sorbitol, glycerin and glycolic compounds. Such substances can be used to replace water to make the product less brittle; where one cannot use oils. The method comprises use of a sequestering agent. Preferably, there are used water and means to remove calcium ions from the water. The method comprises use of means to produce a pH value within a predetermined range, preferably from 3.5 to 7.5, possibly use of a neutralising means. During manufacture, in order to avoid the product setting, it is maintained at a temperature above 40 degrees Centigrade prior to a filling stage. Filling (e. g. of consumer-usable containers) with the product is carried out within a temperature range of from 25 degrees Centigrade to 45 degrees Centigrade. The method may be used to produce a cosmetic composition intermediate product which is not a gel but can be used to produce a cosmetic composition which is a gel. The method may be used to produce a cosmetic composition which is a base to which can
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be added active ingredients and can be used to produce a cosmetic composition which is a gel. The method may comprise the further stage of actually being used to produce a cosmetic composition which is a gel. This may be clear gel, a clear gel containing suspended bubbles of oil, an emulsion, and/or a cosmetic composition which, when applied to the body, can produce an artificial skin thereon.
Embodiments of the invention as a skin product can be made which are much more uniform, with better spreading properties. They are believed to have a low surface tension for the skin. Embodiments of the invention as a makeup product can be made which act as a suspending agent that gives better spreading. These or other embodiments can prevent oils from going rancid. If desired, embodiments can be made to produce a film on the skin, provided that they are not too oily, e. g. due to the active ingredients. Embodiments of the invention can be used to make a thick viscous liquid to thicken a cosmetic product.
Other aspects of the invention comprise: a cosmetic composition, characterised in that it is made by a process comprising a method embodying the invention; a method of treating the human body, characterised in that it comprises use of a cosmetic composition embodying the invention; a human body treated by such a method.
MORE PARTICULAR DESCRIPTION OF EXAMPLES
In one example, the following ingredients are used: water, buffering/sequestering agent, preservatives, gellan gum, structuring agent, carrageenan, active ingredients, neutraliser, solubiliser, absorption enhancer. The buffering/sequestering agent is used to soften the water and remove calcium ions. After considerable experiment, the inventor discovered that suitable ranges of proportions of the gellan gum and
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carrageenan would produce a gel suitable for use as a base for cosmetic products. The ratios or levels of the ingredients will depend upon one's choice of other ingredients.
Some ingredients might interfere with the gelling (i. e. gel formation), and in such cases one will therefore need more gelling agent, e. g. the gellan gum and/or carrageenan. Use of a structuring agent gives the gel a structure which is stable and can hold a large amount of water (and active ingredients dissolved in the water). The gel can be made clear; e. g. the gellan gum as a powder can be added slowly to the water with sequestering/buffering agent and preservatives, and stirred slowly until clear. This is aesthetically pleasing in appearance, which has psychological benefits that produce a psychosomatic beneficial effect on the skin or hair.
The gel has a pleasing appearance likewise when oil bubbles are suspended in the (neutral) gel, e. g. small bubbles (0.25 to 3 mm diameter, preferably 0.5 to 1 or 1.5 mm) of oil-based substance are carried in the water, e. g. vegetable oils, e. g. sweet almond, sunflower, olive, sesame or avocado oil. In such case, the appearance is of small air bubbles in a clear gel, and the product is aesthetically pleasing, attractive and less messy than other methods of applying oil; with bubbles of this size, there is no need for an emulsifier to stabilise the product.
As an alternative, the product can be made into a lotion or cream using the gellan gum and carrageenan as a suspender to form a stable emulsion, though this will normally be white (or can be made coloured); the product will still have the advantages mentioned above of the well-tested and natural ingredients. The oil phase level determines whether the product is an oil or a wax.
Another use of the gel in cosmetics is to form an artificial skin (as is known in food technology); e. g. so that the product in or under this artificial skin, or an
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ingredient thereof, has time to be absorbed by or through the natural skin (of the human being) while minimising disturbance to the substance or to the person; or e. g. to make it longer-lasting, as is advantageous, for example, with a product which is primarily a colorant (e. g. rouge, blusher, skin toner).
In bulk trials, the ingredients shown in the following table were used to make 100 kilogrammes of an arnica balm. The second column shows the weight percentage (as also the number of kilogrammes) in a particular trial, the third column shows the range of percentages in this and other successful trials, and the fourth column indicates the function of each ingredient.
TABLE
INGREDIENT % w/w RANGE FUNCTION Water 80.575 top up vehicle Trisodium citrate 0.130 01-0.5 buffering/sequestering agent Sodium benzoate 0.100 up to 0.1 preservative Potassium sorbate 0.100 up to 0.1 preservative Gellan gum 0.130 0.1-0.5 main ingredient for gel Sorbitol 7.000 5-15 structuring agent Carrageenan 0.400 0.2-1.0 main ingredient for gel Arnica 3.000 * active ingredient Citric acid 0.100 0-0.2 neutraliser or pH adjuster Ginger extract 0.300 * active ingredient Peppermint oil 0.015 * active ingredient Polysorb.20 0.150 5-10 times solubiliser for olis the level of oils Alcohol 8.000 0-10 preservative αabsorption enhancement agent * = 0.1-15 in total (active ingredients)
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In the column 2 trial: (1) The water was heated to 45-50 degrees Centigrade.
In this, there was then dissolved the trisodium citrate. Then there were added the sodium benzoate and potassium sorbate. (2) The gellan gum in powder form was then added slowly with stirring until the product became clear, the time to do so being recorded for use in production. (3) The carrageenan was then dispersed in one kilogramme of the sorbitol, and this together with the remainder of the sorbitol was then added to the bulk (i. e. the product of the last stage so far) (which produced the aforementioned"base") and then the arnica was added to the bulk. (4) The citric acid was dissolved in a small amount of hot water and added to the bulk. (5) The ginger extract and peppermint oil were dissolved in the Polysorb. 20 and added to the bulk, the container which had held the ginger extract and peppermint oil being rinsed out with some of the alcohol then also added to the bulk (because the quantity of these used was relatively so small that a significant proportion had remained in such container. (6) The remainder of the alcohol was then added to the bulk and the mix stirred for two minutes.
The trisodium citrate serves to remove calcium ions in order to hydrate the gellan and obtain a clear gel. The sorbitol can be used to produce the right gel structure for cosmetic purposes; essentially this is less brittle, as is known in the cosmetics art. Instead, more generally, there can be used any one or more chosen from the group comprising sorbitol, glycerin and glycolic compounds, as known in gel chemistry sequestrant techniques. The whole process is carried out warm, i. e. above about 45 degrees Centigrade, which gives a bubble-free product and ease of filling (containers, e. g. bottles, with the product), though the filling can be carried out at any temperature between 45 degree Centigrade and 25 degrees Centigrade, preferably in
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the range 30 to 35 degrees Centigrade. Slight irreversible changes occur if an unused balance of the product is allowed to cool down to room temperature (15 to 20 degrees Centigrade), so that it sets (after two hours), and then is warmed up again for filling at a later time; after such filling, (or alternatively without being warmed up again, i. e. cold filling,) the product is not as cosmetically elegant as before, though it is still usable. The citric acid is used as a neutraliser, e. g. to provide a pH value of 5, the same as the skin. The Polysorb. 20 is a solubiliser (solvent) for the oils in the active ingredients and avoids the product going cloudy because of them. The alcohol partly has a dissolving and preservative action on the oils, and partly serves to increase the rate of absorption of product via the (human) skin.
It will be apparent to one skilled in the art, that features of the different embodiments disclosed herein may be omitted, selected, combined or exchanged and the invention is considered to extend to any new and inventive combination thus formed.
Claims (94)
1. A method of manufacturing a cosmetic composition, characterised in that it comprises use of gellan gum and carrageenan.
2. A method as claimed in claim 1, characterised in that the w/w ratio of gellan gum to carrageenan is substantially in the range of 1: 1 up to 1: 8.
3. A method as claimed in claim 2, characterised in that the w/w ratio of gellan gum to carrageenan is substantially in the range of 1: 2 up to 1: 6.
4. A method as claimed in claim 3, characterised in that the w/w ratio of gellan gum to carrageenan is substantially in the range of 1: 2 up to 1: 3.
5. A method as claimed in any one of claims 1 to 4, characterised in that the gellan gum is used in the proportion of from 0.1 to 0.5 weight per cent of the final product.
6. A method as claimed in any one of claims 1 to 5, characterised in that the carrageenan is used in the proportion of from 0.2 to 1.0 weight per cent of the final product.
7. A method as claimed in any one of claims 1 to 6, characterised in that it comprises use of a structuring agent to reduce or eliminate brittleness.
8. A method as claimed in any one of claims 1 to 6, characterised in that it comprises use of a structuring agent to produce a gel structure suitable for cosmetic purposes.
9. A method as claimed in claim 7 or 8, characterised in that said structuring agent comprises one or more substances chosen from the group comprising polyhydric alcohols and glycerin.
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10. A method as claimed in claim 7 or 8, characterised in that said structuring agent comprises one or more substances chosen from the group comprising sorbitol, glycerin and glycolic compounds.
11. A method as claimed in any one of claims 1 to 10, characterised in that it comprises use of a sequestering agent.
12. A method as claimed in any one of claims 1 to 11, characterised in that it comprises use of means to produce a pH value within a predetermined range.
13. A method as claimed in claim 12, characterised in that said pH value range is from 3.5 to 7.5.
14. A method as claimed in claim 12, characterised in that it comprises use of a neutralising means.
15. A method as claimed in any one of claims 1 to 14, characterised in that the product is maintained at a temperature above 40 degrees Centigrade prior to a filling stage.
16. A method as claimed in claim 15, characterised in that filling with the product is carried out within a temperature range of from 25 degrees Centigrade to 45 degrees Centigrade.
17. A method as claimed in any one of claims 1 to 16, characterised in that it is used to produce a cosmetic composition which is not a gel but can be used to produce a cosmetic composition which is a gel.
18. A method as claimed in any one of claims 1 to 17, characterised in that it is used to produce a cosmetic composition which is a base to which can be added active ingredients and can be used to produce a cosmetic composition which is a gel.
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19. A method as claimed in any one of claims 1 to 18, characterised in that it is used to produce a cosmetic composition which is a gel.
20. A method as claimed in claim 19, characterised in that it is used to produce a clear gel.
21. A method as claimed in claim 19, characterised in that it is used to produce a clear gel containing suspended bubbles of oil.
22. A method as claimed in claim 19, characterised in that it is used to produce an emulsion.
23. A method as claimed in any one of claims 19 to 22, characterised in that it is used to produce a cosmetic composition which, when applied to the body, can produce an artificial skin thereon.
24. A method of producing a cosmetic composition, substantially according to any example hereinbefore described.
25. A cosmetic composition, characterised in that it is made by a process comprising a method as claimed in any one of claims 1 to 19.
26. A cosmetic composition, characterised in that it comprises gellan gum and carrageenan.
27. A cosmetic composition as claimed in claim 26, characterised in that the w/w ratio of gellan gum to carrageenan is substantially in the range of 1: 1 up to 1: 8.
28. A cosmetic composition as claimed in claim 27, characterised in that the w/w ratio of gellan gum to carrageenan is substantially in the range of 1: 2 up to 1: 6.
29. A cosmetic composition as claimed in claim 28, characterised in that the w/w ratio of gellan gum to carrageenan is substantially in the range of 1: 2 up to 1: 3.
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30. A cosmetic composition as claimed in any one of claims 26 to 29, characterised in that the gellan gum is used in the proportion of from 0.1 to 0.5 weight per cent of the final product.
31. A cosmetic composition as claimed in any one of claims 26 to 30, characterised in that the carrageenan is used in the proportion of from 0.2 to 1.0 weight per cent of the final product.
32. A cosmetic composition as claimed in any one of claims 26 to 31, characterised in that it has been made using a structuring agent to reduce or eliminate brittleness.
33. A cosmetic composition as claimed in any one of claims 26 to 31, characterised in that it has been made using a structuring agent to produce a gel structure suitable for cosmetic purposes.
34. A cosmetic composition as claimed in claim 32 or 33, characterised in that said structuring agent comprises one or more substances chosen from the group comprising polyhydric alcohols and glycerin.
35. A cosmetic composition as claimed in claim 32 or 33, characterised in that said structuring agent comprises one or more substances chosen from the group comprising sorbitol, glycerin and glycolic compounds.
36. A cosmetic composition as claimed in any one of claims 26 to 35, characterised in that it has been made using a sequestering agent.
37. A cosmetic composition as claimed in any one of claims 26 to 36, characterised in that it has been made using means to produce a pH value within a predetermined range.
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38. A cosmetic composition as claimed in claim 37, characterised in that said pH value range is from 3.5 to 7.5.
39. A cosmetic composition as claimed in claim 37, characterised in that it has been made using a neutralising means.
40. A cosmetic composition as claimed in any one of claims 26 to 39, characterised in that the product is maintained at a temperature above 40 degrees Centigrade prior to a filling stage.
41. A cosmetic composition as claimed in claim 40, characterised in that filling with the product is carried out within a temperature range of from 25 degrees Centigrade to 45 degrees Centigrade.
42. A cosmetic composition as claimed in any one of claims 26 to 41, characterised in that it is used to produce a cosmetic composition which is not a gel but can be used to produce a cosmetic composition which is a gel.
43. A cosmetic composition as claimed in any one of claims 26 to 42, characterised in that it is used to produce a cosmetic composition which is a base to which can be added active ingredients and can be used to produce a cosmetic composition which is a gel.
44. A cosmetic composition, substantially according to any example hereinbefore described.
45. A method of treating the human body, characterised in that it comprises use of a cosmetic composition as claimed in any one of claims 25 to 44.
46. A human body treated by a method as claimed in claim 45.
47. A method of manufacturing a cosmetic composition in the form of a fluid gel, characterised in that it comprises use of gellan gum and carrageenan.
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48. A method as claimed in claim 47, characterised in that the w/w ratio of gellan gum to carrageenan is substantially in the range of 1: 1 up to 1: 8.
49. A method as claimed in claim 48, characterised in that the w/w ratio of gellan gum to carrageenan is substantially in the range of 1: 2 up to 1: 6.
50. A method as claimed in claim 49, characterised in that the w/w ratio of gellan gum to carrageenan is substantially in the range of 1: 2 up to 1: 3.
51. A method as claimed in any one of claims 47 to 50, characterised in that the gellan gum is used in the proportion of from 0.1 to 0.5 weight per cent of the final product.
52. A method as claimed in any one of claims 47 to 51, characterised in that the carrageenan is used in the proportion of from 0.2 to 1.0 weight per cent of the final product.
53. A method as claimed in any one of claims 47 to 52, characterised in that it comprises use of a structuring agent to reduce or eliminate brittleness.
54. A method as claimed in any one of claims 47 to 52, characterised in that it comprises use of a structuring agent to produce a gel structure suitable for cosmetic purposes.
55. A method as claimed in claim 53 or 54, characterised in that said structuring agent comprises one or more substances chosen from the group comprising polyhydric alcohols and glycerin.
56. A method as claimed in claim 53 or 54, characterised in that said structuring agent comprises one or more substances chosen from the group comprising sorbitol, glycerin and glycolic compounds.
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57. A method as claimed in any one of claims 47 to 56, characterised in that it comprises use of a sequestering agent.
58. A method as claimed in any one of claims 53 to 56, characterised in that it comprises use of a sequestering agent.
59. A method as claimed in any one of claims 47 to 57, characterised in that it comprises use of means to produce a pH value within a predetermined range.
60. A method as claimed in claim 58 or 59, characterised in that said pH value range is from 3.5 to 7.5.
61. A method as claimed in claim 58 or 59, characterised in that it comprises use of a neutralising means.
62. A method as claimed in any one of claims 47 to 61, characterised in that the product is maintained at a temperature above 40 degrees Centigrade prior to a filling stage.
63. A method as claimed in claim 62, characterised in that filling with the product is carried out within a temperature range of from 25 degrees Centigrade to 45 degrees Centigrade.
64. A method as claimed in any one of claims 47 to 63, characterised in that it is used to produce a cosmetic composition which is not a fluid gel but can be used to produce a cosmetic composition which is a fluid gel.
65. A method as claimed in any one of claims 47 to 64, characterised in that it is used to produce a cosmetic composition which is a base to which can be added active ingredients and can be used to produce a cosmetic composition which is a fluid gel.
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66. A method as claimed in any one of claims 47 to 65, characterised in that it is used to produce a cosmetic composition which is a fluid gel.
67. A method as claimed in claim 66, characterised in that it is used to produce a clear fluid gel.
68. A method as claimed in claim 66, characterised in that it is used to produce a clear fluid gel containing suspended bubbles of oil.
69. A method as claimed in claim 66, characterised in that it is used to produce an emulsion.
70. A method as claimed in any one of claims 66 to 69, characterised in that it is used to produce a cosmetic composition which, when applied to the body, can produce an artificial skin thereon.
71. A method of producing a cosmetic composition, substantially according to any example hereinbefore described.
72. A cosmetic composition, characterised in that it is made by a process comprising a method as claimed in any one of claims 47 to 71.
73. A cosmetic composition in the form of a fluid gel, characterised in that it comprises gellan gum and carrageenan.
74. A cosmetic composition as claimed in claim 73, characterised in that the w/w ratio of gellan gum to carrageenan is substantially in the range of 1: 1 up to 1: 8.
75. A cosmetic composition as claimed in claim 74, characterised in that the w/w ratio of gellan gum to carrageenan is substantially in the range of 1: 2 up to 1: 6.
76. A cosmetic composition as claimed in claim 75, characterised in that the w/w ratio of gellan gum to carrageenan is substantially in the range of 1: 2 up to 1: 3.
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77. A cosmetic composition as claimed in any one of claims 73 to 76, characterised in that the gellan gum is used in the proportion of from 0.1 to 0.5 weight per cent of the final product.
78. A cosmetic composition as claimed in any one of claims 73 to 77, characterised in that the carrageenan is used in the proportion of from 0.2 to 1.0 weight per cent of the final product.
79. A cosmetic composition as claimed in any one of claims 73 to 78, characterised in that it has been made using a structuring agent to reduce or eliminate brittleness.
80. A cosmetic composition as claimed in any one of claims 73 to 79, characterised in that it has been made using a structuring agent to produce a fluid gel structure suitable for cosmetic purposes.
81. A cosmetic composition as claimed in claim 79 or 80, characterised in that said structuring agent comprises one or more substances chosen from the group comprising polyhydric alcohols and glycerin.
82. A cosmetic composition as claimed in claim 79 or 80, characterised in that said structuring agent comprises one or more substances chosen from the group comprising sorbitol, glycerin and glycolic compounds.
83. A cosmetic composition as claimed in any one of claims 73 to 82, characterised in that it has been made using a sequestering agent.
84. A cosmetic composition as claimed in any one of claims 79 to 82, characterised in that it has been made using a sequestering agent.
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85. A cosmetic composition as claimed in any one of claims 73 to 84, characterised in that it has been made using means to produce a pH value within a predetermined range.
86. A cosmetic composition as claimed in claim 85, characterised in that said pH value range is from 3.5 to 7.5.
87. A cosmetic composition as claimed in claim 85, characterised in that it has been made using a neutralising means.
88. A cosmetic composition as claimed in any one of claims 73 to 87, characterised in that the product is maintained at a temperature above 40 degrees Centigrade prior to a filling stage.
89. A cosmetic composition as claimed in claim 88, characterised in that filling with the product is carried out within a temperature range of from 25 degrees Centigrade to 45 degrees Centigrade.
90. A cosmetic composition as claimed in any one of claims 73 to 89, characterised in that it is used to produce a cosmetic composition which is not a fluid gel but can be used to produce a cosmetic composition which is a fluid gel.
91. A cosmetic composition as claimed in any one of claims 73 to 90, characterised in that it is used to produce a cosmetic composition which is a base to which can be added active ingredients and can be used to produce a cosmetic composition which is a fluid gel.
92. A cosmetic composition, substantially according to any example hereinbefore described.
93. A method of treating the human body, characterised in that it comprises use of a cosmetic composition as claimed in any one of claims 72 to 92.
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94. A human body treated by a method as claimed in claim 93.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0200204A GB2384705B (en) | 2002-01-07 | 2002-01-07 | Cosmetic and related compositions |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0200204A GB2384705B (en) | 2002-01-07 | 2002-01-07 | Cosmetic and related compositions |
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| GB0200204D0 GB0200204D0 (en) | 2002-02-20 |
| GB2384705A true GB2384705A (en) | 2003-08-06 |
| GB2384705B GB2384705B (en) | 2006-09-27 |
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| GB0200204A Expired - Fee Related GB2384705B (en) | 2002-01-07 | 2002-01-07 | Cosmetic and related compositions |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2862221A1 (en) * | 2003-11-18 | 2005-05-20 | Oreal | COSMETIC COMPOSITION COMPRISING GELLANE GUM OR A DERIVATIVE, A MONOVALENT SALT AND A SUSPENDED COMPOUND, METHODS USING THE SAME AND USES THEREOF |
| FR2862222A1 (en) * | 2003-11-18 | 2005-05-20 | Oreal | COSMETIC COMPOSITION COMPRISING GELLANE GUM OR ONE OF ITS DERIVATIVES, A SOLID COMPOUND AND A MONOVALENT SALT, PROCESSES USING THE SAME, AND USES THEREOF |
| DE102004040849A1 (en) * | 2004-08-23 | 2006-03-02 | Henkel Kgaa | Clear washing and cleaning agent with yield point |
| US7015181B2 (en) | 2004-03-08 | 2006-03-21 | Lambino Danilo L | Rehydratable personal care compositions |
| WO2010143196A1 (en) * | 2009-04-03 | 2010-12-16 | Cavinkare Pvt Ltd. | Novel synergistic transparent / translucent hydrogel composition; method of preparing it and a sheet / film made thereform |
| US8246940B2 (en) | 2003-11-18 | 2012-08-21 | L'oreal S.A. | Cosmetic composition comprising gellan gum or a derivative thereof, a fixing polymer, a monovalent salt and an alcohol, process of using the same |
| US8399001B2 (en) | 2003-11-18 | 2013-03-19 | L'oreal | Cosmetic composition comprising at least one gellan gum or derivative thereof, at least one monovalent salt, and at least one suspension compound, processes using this composition, and uses thereof |
| US9872826B2 (en) | 2012-12-03 | 2018-01-23 | Colgate-Palmolive Company | Manufacturing processes for gellan gum-based fluid gels |
| WO2021101458A1 (en) * | 2019-11-21 | 2021-05-27 | Cetin Aydin | Lotion for hair and hair skin |
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2862221A1 (en) * | 2003-11-18 | 2005-05-20 | Oreal | COSMETIC COMPOSITION COMPRISING GELLANE GUM OR A DERIVATIVE, A MONOVALENT SALT AND A SUSPENDED COMPOUND, METHODS USING THE SAME AND USES THEREOF |
| FR2862222A1 (en) * | 2003-11-18 | 2005-05-20 | Oreal | COSMETIC COMPOSITION COMPRISING GELLANE GUM OR ONE OF ITS DERIVATIVES, A SOLID COMPOUND AND A MONOVALENT SALT, PROCESSES USING THE SAME, AND USES THEREOF |
| EP1532968A1 (en) * | 2003-11-18 | 2005-05-25 | L'oreal | Cosmetic composition comprising gellan gum or a derivative thereof, a monovalent salt and a compound in suspension, process using this composition and uses thereof |
| EP1532967A1 (en) * | 2003-11-18 | 2005-05-25 | L'oreal | Cosmetic composition comprising gellan gum or a derivative thereof, a solid compound and an alcohol, processes using this composition and uses thereof |
| US8246940B2 (en) | 2003-11-18 | 2012-08-21 | L'oreal S.A. | Cosmetic composition comprising gellan gum or a derivative thereof, a fixing polymer, a monovalent salt and an alcohol, process of using the same |
| US8399001B2 (en) | 2003-11-18 | 2013-03-19 | L'oreal | Cosmetic composition comprising at least one gellan gum or derivative thereof, at least one monovalent salt, and at least one suspension compound, processes using this composition, and uses thereof |
| US7015181B2 (en) | 2004-03-08 | 2006-03-21 | Lambino Danilo L | Rehydratable personal care compositions |
| DE102004040849A1 (en) * | 2004-08-23 | 2006-03-02 | Henkel Kgaa | Clear washing and cleaning agent with yield point |
| US7749332B2 (en) | 2004-08-23 | 2010-07-06 | Henkel Kgaa | Detergent/cleaning agents with a gellan gum thickening system, methods for using the same and cleaning substrates containing the same |
| WO2010143196A1 (en) * | 2009-04-03 | 2010-12-16 | Cavinkare Pvt Ltd. | Novel synergistic transparent / translucent hydrogel composition; method of preparing it and a sheet / film made thereform |
| US9872826B2 (en) | 2012-12-03 | 2018-01-23 | Colgate-Palmolive Company | Manufacturing processes for gellan gum-based fluid gels |
| WO2021101458A1 (en) * | 2019-11-21 | 2021-05-27 | Cetin Aydin | Lotion for hair and hair skin |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2384705B (en) | 2006-09-27 |
| GB0200204D0 (en) | 2002-02-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20130107 |