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GB2361869B - Sublingual delivery of cannabis - Google Patents

Sublingual delivery of cannabis

Info

Publication number
GB2361869B
GB2361869B GB0005718A GB0005718A GB2361869B GB 2361869 B GB2361869 B GB 2361869B GB 0005718 A GB0005718 A GB 0005718A GB 0005718 A GB0005718 A GB 0005718A GB 2361869 B GB2361869 B GB 2361869B
Authority
GB
United Kingdom
Prior art keywords
cannabis
sublingual delivery
sublingual
delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB0005718A
Other versions
GB0005718D0 (en
GB2361869A (en
Inventor
Calvin Ross
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GW Pharma Ltd
Pharmasol Ltd
Original Assignee
GW Pharma Ltd
Pharmasol Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GW Pharma Ltd, Pharmasol Ltd filed Critical GW Pharma Ltd
Priority to GB0005718A priority Critical patent/GB2361869B/en
Publication of GB0005718D0 publication Critical patent/GB0005718D0/en
Priority to MXPA02008778A priority patent/MXPA02008778A/en
Priority to PCT/GB2001/001027 priority patent/WO2001066089A2/en
Priority to PT01910026T priority patent/PT1280515E/en
Priority to DE60126599T priority patent/DE60126599T2/en
Priority to KR1020027011818A priority patent/KR20030038536A/en
Priority to AU37608/01A priority patent/AU782991B2/en
Priority to DK01910026T priority patent/DK1280515T3/en
Priority to PL365005A priority patent/PL202673B1/en
Priority to CZ20023017A priority patent/CZ303537B6/en
Priority to CA002402020A priority patent/CA2402020C/en
Priority to SI200130712T priority patent/SI1280515T1/en
Priority to NZ544681A priority patent/NZ544681A/en
Priority to US10/221,066 priority patent/US20030191180A1/en
Priority to ES01910026T priority patent/ES2280343T3/en
Priority to CNB018092640A priority patent/CN1258359C/en
Priority to JP2001564742A priority patent/JP5599961B2/en
Priority to HU0300582A priority patent/HU228237B1/en
Priority to EP01910026A priority patent/EP1280515B1/en
Priority to AT01910026T priority patent/ATE353629T1/en
Priority to IL15160301A priority patent/IL151603A0/en
Publication of GB2361869A publication Critical patent/GB2361869A/en
Priority to HK02103066.1A priority patent/HK1041446B/en
Priority to NO20024222A priority patent/NO332663B1/en
Priority to IL151603A priority patent/IL151603A/en
Priority to ZA200207161A priority patent/ZA200207161B/en
Publication of GB2361869B publication Critical patent/GB2361869B/en
Application granted granted Critical
Priority to CY20071100569T priority patent/CY1106549T1/en
Priority to US11/901,593 priority patent/US20080071233A1/en
Priority to US12/853,387 priority patent/US20100323038A1/en
Priority to DE201112100060 priority patent/DE122011100060I1/en
Priority to US13/606,742 priority patent/US8512767B2/en
Priority to US13/607,897 priority patent/US8481091B2/en
Priority to NO2013011C priority patent/NO2013011I2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/658Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/348Cannabaceae
    • A61K36/3482Cannabis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB0005718A 2000-03-09 2000-03-09 Sublingual delivery of cannabis Expired - Lifetime GB2361869B (en)

Priority Applications (32)

Application Number Priority Date Filing Date Title
GB0005718A GB2361869B (en) 2000-03-09 2000-03-09 Sublingual delivery of cannabis
JP2001564742A JP5599961B2 (en) 2000-03-09 2001-03-09 Pharmaceutical composition
PCT/GB2001/001027 WO2001066089A2 (en) 2000-03-09 2001-03-09 Pharmaceutical compositions comprising cannabis
PT01910026T PT1280515E (en) 2000-03-09 2001-03-09 PHARMACEUTICAL COMPARISONS UNDERTAKING CANOTHES
DE60126599T DE60126599T2 (en) 2000-03-09 2001-03-09 CANNABIS CONTAINING PHARMACEUTICAL COMPOSITIONS
KR1020027011818A KR20030038536A (en) 2000-03-09 2001-03-09 Pharmaceutical Compositions
AU37608/01A AU782991B2 (en) 2000-03-09 2001-03-09 Pharmaceutical compositions
DK01910026T DK1280515T3 (en) 2000-03-09 2001-03-09 Pharmaceutical compositions comprising cannabis
PL365005A PL202673B1 (en) 2000-03-09 2001-03-09 Pharmaceutical compositions
CZ20023017A CZ303537B6 (en) 2000-03-09 2001-03-09 The use of cannabis in the preparation of a pharmaceutical formulation and a pump spray device
CA002402020A CA2402020C (en) 2000-03-09 2001-03-09 Pharmaceutical compositions
SI200130712T SI1280515T1 (en) 2000-03-09 2001-03-09 Pharmaceutical compositions comprising cannabis
NZ544681A NZ544681A (en) 2000-03-09 2001-03-09 Sub-lingual administration of cannabis
US10/221,066 US20030191180A1 (en) 2000-03-09 2001-03-09 Pharmaceutical compositions
ES01910026T ES2280343T3 (en) 2000-03-09 2001-03-09 PHARMACEUTICAL COMPOSITIONS CONTAINING CANNABIS.
CNB018092640A CN1258359C (en) 2000-03-09 2001-03-09 Pharmaceutical compositions
MXPA02008778A MXPA02008778A (en) 2000-03-09 2001-03-09 Pharmaceutical compositions.
EP01910026A EP1280515B1 (en) 2000-03-09 2001-03-09 Pharmaceutical compositions comprising cannabis
HU0300582A HU228237B1 (en) 2000-03-09 2001-03-09 Pharmaceutical compositions comprising cannabis and a pump spray device for the delivery of the compositions
AT01910026T ATE353629T1 (en) 2000-03-09 2001-03-09 PHARMACEUTICAL COMPOSITIONS CONTAINING CANNABIS
IL15160301A IL151603A0 (en) 2000-03-09 2001-03-09 A pharmaceutical composition containing cannabis and devices for delivering the same
HK02103066.1A HK1041446B (en) 2000-03-09 2002-04-24 Sublingual delivery of cannabis
NO20024222A NO332663B1 (en) 2000-03-09 2002-09-04 Use of cannabis, a liquid extract or delta-9-tatrahydrocannabinol or a pharmaceutical derivative thereof for therapeutic treatment of a patient by the sublingual route, and pump sparing device
IL151603A IL151603A (en) 2000-03-09 2002-09-04 Pharmaceutical composition containing cannabis and devices for delivering the same
ZA200207161A ZA200207161B (en) 2000-03-09 2002-09-05 Pharmaceutical compositions.
CY20071100569T CY1106549T1 (en) 2000-03-09 2007-04-26 PHARMACEUTICAL COMPOSITIONS CONTAINING CANNABIS
US11/901,593 US20080071233A1 (en) 2000-03-09 2007-09-18 Pharmaceutical compositions
US12/853,387 US20100323038A1 (en) 2000-03-09 2010-08-10 Pharmaceutical Compositions
DE201112100060 DE122011100060I1 (en) 2000-03-09 2011-11-17 Cannabis-containing pharmaceutical compositions.
US13/606,742 US8512767B2 (en) 2000-03-09 2012-09-07 Pharmaceutical compositions
US13/607,897 US8481091B2 (en) 2000-03-09 2012-09-10 Pharmaceutical compositions
NO2013011C NO2013011I2 (en) 2000-03-09 2013-05-24 A mixture of two extracts from Cannabis sativa L., folicum cum flore (cannabis leaf and flower).

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0005718A GB2361869B (en) 2000-03-09 2000-03-09 Sublingual delivery of cannabis

Publications (3)

Publication Number Publication Date
GB0005718D0 GB0005718D0 (en) 2000-05-03
GB2361869A GB2361869A (en) 2001-11-07
GB2361869B true GB2361869B (en) 2004-09-22

Family

ID=9887303

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0005718A Expired - Lifetime GB2361869B (en) 2000-03-09 2000-03-09 Sublingual delivery of cannabis

Country Status (3)

Country Link
GB (1) GB2361869B (en)
HK (1) HK1041446B (en)
ZA (1) ZA200207161B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10004684B2 (en) 2001-02-14 2018-06-26 Gw Pharma Limited Pharmaceutical formulations
GB2381194A (en) * 2001-09-07 2003-04-30 Gw Pharmaceuticals Ltd Pharmaceutical formulations
US10538373B2 (en) 2002-08-14 2020-01-21 Gw Pharma Limited Pharmaceutical formulation
US6946150B2 (en) 2002-08-14 2005-09-20 Gw Pharma Limited Pharmaceutical formulation
GB2524469A (en) 2014-02-14 2015-09-30 Kind Consumer Ltd A cannabinoid inhaler and composition therefor
WO2022011460A1 (en) * 2020-07-13 2022-01-20 Hexo Operations Inc. Transmucosal cannabis compositions with enhanced permeation properties
WO2025129263A1 (en) * 2023-12-21 2025-06-26 InhaleRx Ltd Treatment of breakthrough cancer pain

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0266443A1 (en) * 1986-11-03 1988-05-11 Allen W. Jacobs Process for the inclusion of a solid particulate component into aerosol formulations of inhalable nicotine
WO1999032107A1 (en) * 1997-12-19 1999-07-01 West Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited Compositions comprising cannabinoids
WO2000024362A2 (en) * 1998-10-27 2000-05-04 Virginia Commonwealth University Δ9 tetrahydrocannabinol (δ9 thc) solution metered dose inhalers and methods of use
WO2000045813A1 (en) * 1999-02-04 2000-08-10 New Millennium Pharmaceutical Research, Inc. Method for enhancement of delivery of thc by the administration of its prodrugs via the nasal route
WO2001013886A1 (en) * 1999-08-20 2001-03-01 Roxane Laboratories, Inc. Composition for inhalation comprising delta-9-tetrahydrocannabinol in a semiaqueous solvent

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0266443A1 (en) * 1986-11-03 1988-05-11 Allen W. Jacobs Process for the inclusion of a solid particulate component into aerosol formulations of inhalable nicotine
WO1999032107A1 (en) * 1997-12-19 1999-07-01 West Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited Compositions comprising cannabinoids
WO2000024362A2 (en) * 1998-10-27 2000-05-04 Virginia Commonwealth University Δ9 tetrahydrocannabinol (δ9 thc) solution metered dose inhalers and methods of use
WO2000045813A1 (en) * 1999-02-04 2000-08-10 New Millennium Pharmaceutical Research, Inc. Method for enhancement of delivery of thc by the administration of its prodrugs via the nasal route
WO2001013886A1 (en) * 1999-08-20 2001-03-01 Roxane Laboratories, Inc. Composition for inhalation comprising delta-9-tetrahydrocannabinol in a semiaqueous solvent

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Chemical Senses Vol. 19, No. 2, 1994, R D Mattes, et al *
Pharmacology, Biochemistry and Behavior Vol. 49, No.1, 1994,pages 187-195 *

Also Published As

Publication number Publication date
ZA200207161B (en) 2003-12-05
GB0005718D0 (en) 2000-05-03
GB2361869A (en) 2001-11-07
HK1041446B (en) 2005-05-13
HK1041446A1 (en) 2002-07-12

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