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GB2212511B - Hepatitis c virus - Google Patents

Hepatitis c virus

Info

Publication number
GB2212511B
GB2212511B GB8827024A GB8827024A GB2212511B GB 2212511 B GB2212511 B GB 2212511B GB 8827024 A GB8827024 A GB 8827024A GB 8827024 A GB8827024 A GB 8827024A GB 2212511 B GB2212511 B GB 2212511B
Authority
GB
United Kingdom
Prior art keywords
hepatitis
virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8827024A
Other versions
GB2212511A (en
GB8827024D0 (en
Inventor
Michael Houghton
Qui-Lim Choo
George Kuo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27537644&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB2212511(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of GB8827024D0 publication Critical patent/GB8827024D0/en
Publication of GB2212511A publication Critical patent/GB2212511A/en
Application granted granted Critical
Publication of GB2212511B publication Critical patent/GB2212511B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/706Specific hybridization probes for hepatitis
    • C12Q1/707Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GB8827024A 1987-11-18 1988-11-18 Hepatitis c virus Expired - Lifetime GB2212511B (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12271487A 1987-11-18 1987-11-18
US13988687A 1987-12-30 1987-12-30
US16107288A 1988-02-26 1988-02-26
US19126388A 1988-05-06 1988-05-06
US26358488A 1988-10-26 1988-10-26

Publications (3)

Publication Number Publication Date
GB8827024D0 GB8827024D0 (en) 1988-12-21
GB2212511A GB2212511A (en) 1989-07-26
GB2212511B true GB2212511B (en) 1992-01-22

Family

ID=27537644

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8827024A Expired - Lifetime GB2212511B (en) 1987-11-18 1988-11-18 Hepatitis c virus

Country Status (3)

Country Link
GB (1) GB2212511B (en)
SG (1) SG102092G (en)
YU (1) YU48038B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7049428B1 (en) 1998-03-04 2006-05-23 Washington University HCV variants
US7070790B1 (en) 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US7241879B2 (en) 2000-06-15 2007-07-10 Novartis Vaccines And Diagnostics, Inc. Immunoassays for anti-HCV antibodies

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6171782B1 (en) 1987-11-18 2001-01-09 Chiron Corporation Antibody compositions to HCV and uses thereof
US5714596A (en) * 1987-11-18 1998-02-03 Chiron Corporation NANBV diagnostics: polynucleotides useful for screening for hepatitis C virus
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US5698390A (en) 1987-11-18 1997-12-16 Chiron Corporation Hepatitis C immunoassays
US5712088A (en) * 1987-11-18 1998-01-27 Chiron Corporation Methods for detecting Hepatitis C virus using polynucleotides specific for same
US5683864A (en) * 1987-11-18 1997-11-04 Chiron Corporation Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
US6861212B1 (en) 1987-11-18 2005-03-01 Chiron Corporation NANBV diagnostics and vaccines
US6027729A (en) * 1989-04-20 2000-02-22 Chiron Corporation NANBV Diagnostics and vaccines
FI906208A7 (en) 1989-12-18 1991-06-19 The Wellcome Foundation Ltd Viral agents
US7166287B1 (en) 1989-12-18 2007-01-23 Glaxo Wellcome Inc. Viral agent
US5712087A (en) * 1990-04-04 1998-01-27 Chiron Corporation Immunoassays for anti-HCV antibodies employing combinations of hepatitis C virus (HCV) antigens
US6194140B1 (en) * 1990-04-04 2001-02-27 Chiron Corporation HCV NS3 protein fragments having helicase activity and improved solubility
US6172189B1 (en) * 1990-08-24 2001-01-09 Abbott Laboratories Hepatitis C assay utilizing recombinant antigens
ES2098511T3 (en) * 1991-03-26 1997-05-01 Dade Int Inc DIAGNOSIS PROCEDURE FOR HEPATITIS NO-A NO-B.
US5574132A (en) * 1991-04-05 1996-11-12 Biochem Immunosystems Inc. Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV)
WO1993000365A2 (en) * 1991-06-24 1993-01-07 Chiron Corporation Hepatitis c virus (hcv) polypeptides
WO1993015193A1 (en) * 1992-01-31 1993-08-05 Abbott Laboratories Mammalian expression systems for hcv proteins
US6620414B2 (en) 1992-03-27 2003-09-16 Smithkline Beecham Biologicals (S.A.) Hepatitis vaccines containing 3-0-deacylated monophoshoryl lipid A
US5514539A (en) * 1993-06-29 1996-05-07 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US5610009A (en) * 1994-01-28 1997-03-11 Abbott Laboratories Mammalian expression systems for hepatitis C virus envelope genes
BR9506059A (en) * 1994-07-29 1997-10-28 Innogenetics Nv Virus c purified envelope proteins for diagnostic and therapeutic use
US6107027A (en) * 1994-12-14 2000-08-22 University Of Washington Ribozymes for treating hepatitis C
US6127116A (en) * 1995-08-29 2000-10-03 Washington University Functional DNA clone for hepatitis C virus (HCV) and uses thereof
US7338759B1 (en) 1997-03-04 2008-03-04 Washington University HCV variants
EP3313863B1 (en) * 2015-06-29 2020-12-23 The Board of Trustees of the Leland Stanford Junior University Degron fusion constructs and methods for controlling protein production
CN107286237B (en) * 2017-08-07 2020-04-03 广州泰诺迪生物科技有限公司 Acquisition and application of an anti-hepatitis C virus antibody

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982000205A1 (en) * 1980-07-09 1982-01-21 Baxter Travenol Lab Non-a,non-b hepatitis assay and vaccine
WO1982002774A1 (en) * 1981-02-11 1982-08-19 Baxter Travenol Lab Non-a,non-b hepatitis virus
EP0061974A2 (en) * 1981-03-27 1982-10-06 Institut Merieux New vaccine and therapy against non-A non-B viral hepatitis, and their preparation process
WO1982003330A1 (en) * 1981-03-30 1982-10-14 Christian Trepo Method for the preparation of antigens of the viral hepatitis nanb,and application to the preparation of a reaction agent allowing the diagnostic and pronostic of infections caused by the viruses of viral hepatitis
WO1988003410A1 (en) * 1986-11-07 1988-05-19 Pasteur Institut Viral agent for nanb hepatitis, antigen and immunologic reagent
US4895976A (en) * 1988-05-23 1990-01-23 E. I. Du Pont De Nemours And Company Preparation of 4-pentanoates by isomerization

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982000205A1 (en) * 1980-07-09 1982-01-21 Baxter Travenol Lab Non-a,non-b hepatitis assay and vaccine
WO1982002774A1 (en) * 1981-02-11 1982-08-19 Baxter Travenol Lab Non-a,non-b hepatitis virus
EP0061974A2 (en) * 1981-03-27 1982-10-06 Institut Merieux New vaccine and therapy against non-A non-B viral hepatitis, and their preparation process
WO1982003330A1 (en) * 1981-03-30 1982-10-14 Christian Trepo Method for the preparation of antigens of the viral hepatitis nanb,and application to the preparation of a reaction agent allowing the diagnostic and pronostic of infections caused by the viruses of viral hepatitis
WO1988003410A1 (en) * 1986-11-07 1988-05-19 Pasteur Institut Viral agent for nanb hepatitis, antigen and immunologic reagent
EP0277437A1 (en) * 1986-11-07 1988-08-10 Institut Pasteur Hepatitis NANB viral agent, antigen and immunological reagent
US4895976A (en) * 1988-05-23 1990-01-23 E. I. Du Pont De Nemours And Company Preparation of 4-pentanoates by isomerization

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
Chiron News Release 1988, May 10, 21 Lancet 1978, 21 October, 8095 *
Gastroenteralogy 1979,77(5),A33 (30th Annual Meeting of the American Association for the study of li *
Immun. Infect. 1988, 16(3), 91-96 *
Immun. Infect. 1988, 16(3), 97-99 *
Naturwissenschaften 1986, 73(1)45-46 *
ver disease, Chicago, Ill., USA, Nov. 7, 1979) Postgrad. Med. USA 1980, 68(5), 66-86 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7070790B1 (en) 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US7049428B1 (en) 1998-03-04 2006-05-23 Washington University HCV variants
US7241879B2 (en) 2000-06-15 2007-07-10 Novartis Vaccines And Diagnostics, Inc. Immunoassays for anti-HCV antibodies

Also Published As

Publication number Publication date
GB2212511A (en) 1989-07-26
YU213888A (en) 1991-02-28
YU48038B (en) 1996-10-18
GB8827024D0 (en) 1988-12-21
SG102092G (en) 1992-12-24

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Legal Events

Date Code Title Description
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
775B Specification amended (sect. 75/1977)
SP Amendment (slips) printed
775L Amendment of patent in infringement or revocation proceedings. application to amend not proceeded with (sect. 75/1977)
SP Amendment (slips) printed
SP Amendment (slips) printed
PE20 Patent expired after termination of 20 years

Expiry date: 20081117