GB2210620B - Cloning and expression of transforming growth factor ¼2 - Google Patents

Cloning and expression of transforming growth factor ¼2

Info

Publication number: GB2210620B
Authority: GB; United Kingdom
Prior art keywords: cloning; expression; growth factor; transforming growth; transforming
Prior art date: 1987-10-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

GB8823448A

Other versions

GB2210620A (en

GB8823448D0 (en

GB2210620B8 (en

Inventor

Anthony F Purchio

Linda Madisen

Nancy Webb

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Oncogen LP

Original Assignee

Oncogen LP

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-06

Filing date

1988-10-06

Publication date

1992-07-08

1988-10-06 Application filed by Oncogen LP filed Critical Oncogen LP

1988-11-16 Publication of GB8823448D0 publication Critical patent/GB8823448D0/en

1989-06-14 Publication of GB2210620A publication Critical patent/GB2210620A/en

1992-07-08 Application granted granted Critical

1992-07-08 Publication of GB2210620B publication Critical patent/GB2210620B/en

1995-07-17 Publication of GB2210620B8 publication Critical patent/GB2210620B8/en

2008-10-06 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Microbiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

GB8823448A 1987-10-06 1988-10-06 Cloning and expression of transforming growth factor beta2 Expired - Fee Related GB2210620B8 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US10675287A	1987-10-06	1987-10-06
US14826788A	1988-01-25	1988-01-25
US23406588A	1988-08-18	1988-08-18

Publications (4)

Publication Number	Publication Date
GB8823448D0 GB8823448D0 (en)	1988-11-16
GB2210620A GB2210620A (en)	1989-06-14
GB2210620B true GB2210620B (en)	1992-07-08
GB2210620B8 GB2210620B8 (en)	1995-07-17

Family

ID=27380183

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GB8823448A Expired - Fee Related GB2210620B8 (en)	1987-10-06	1988-10-06	Cloning and expression of transforming growth factor beta2

Country Status (22)

Country	Link
JP (1)	JPH02444A (en)
KR (1)	KR970001236B1 (en)
CN (1)	CN1035845A (en)
AT (1)	AT398433B (en)
BE (1)	BE1002693A5 (en)
CH (1)	CH680002A5 (en)
DE (1)	DE3833897C2 (en)
DK (1)	DK556388A (en)
ES (1)	ES2012556A6 (en)
FI (1)	FI884546A7 (en)
FR (1)	FR2621324B1 (en)
GB (1)	GB2210620B8 (en)
GR (1)	GR1000492B (en)
IE (1)	IE60918B1 (en)
IL (1)	IL87877A0 (en)
IT (1)	IT1227957B (en)
MY (1)	MY103779A (en)
NL (1)	NL8802442A (en)
NO (1)	NO884429L (en)
NZ (1)	NZ226486A (en)
PT (1)	PT88670B (en)
SE (1)	SE8803528L (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5221620A (en) *	1987-10-06	1993-06-22	Oncogen	Cloning and expression of transforming growth factor β2
US5445941A (en) *	1993-06-21	1995-08-29	Eli Lilly And Company	Method for screening anti-osteoporosis agents
CN100389120C (en) *	2005-04-12	2008-05-21	中国人民解放军第三军医大学野战外科研究所	Sealing TGF-betal antisensedingonucleotides and its use in preparing medicine for treating fibrillation related disease

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1988005788A1 (en) *	1987-01-30	1988-08-11	Techne Corporation	Tranforming growth factor-beta
EP0290012A1 (en) *	1987-05-04	1988-11-09	Oncogen	TGF-B2 and novel compositions having anti-neoplastic activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0169016B2 (en) *	1984-07-16	2004-04-28	Celtrix Pharmaceuticals, Inc.	Polypeptide cartilage-inducing factors found in bone
IL78197A (en) *	1985-03-22	1991-07-18	Genentech Inc	Nucleic acid encoding tgf-beta and its uses
NZ222569A (en) *	1986-11-17	1990-08-28	Sandoz Ltd	Production of glioblastoma-derived t cell suppressor factor (g-tsf) using recombinant techniques
WO1988005787A1 (en) *	1987-01-30	1988-08-11	Techne Corporation	Transforming growth factor-beta

1988
- 1988-09-29 IL IL87877A patent/IL87877A0/en active Protection Beyond IP Right Term
- 1988-10-03 FI FI884546A patent/FI884546A7/en not_active IP Right Cessation
- 1988-10-04 PT PT88670A patent/PT88670B/en not_active IP Right Cessation
- 1988-10-04 MY MYPI88001108A patent/MY103779A/en unknown
- 1988-10-05 SE SE8803528A patent/SE8803528L/en not_active Application Discontinuation
- 1988-10-05 NO NO88884429A patent/NO884429L/en unknown
- 1988-10-05 BE BE8801141A patent/BE1002693A5/en not_active IP Right Cessation
- 1988-10-05 NL NL8802442A patent/NL8802442A/en not_active Application Discontinuation
- 1988-10-05 IE IE301888A patent/IE60918B1/en not_active IP Right Cessation
- 1988-10-05 AT AT0245488A patent/AT398433B/en not_active IP Right Cessation
- 1988-10-05 GR GR880100660A patent/GR1000492B/en unknown
- 1988-10-05 DE DE3833897A patent/DE3833897C2/en not_active Expired - Fee Related
- 1988-10-05 KR KR1019880012986A patent/KR970001236B1/en not_active Expired - Lifetime
- 1988-10-05 FR FR8813046A patent/FR2621324B1/en not_active Expired - Fee Related
- 1988-10-05 DK DK556388A patent/DK556388A/en not_active Application Discontinuation
- 1988-10-05 ES ES8803023A patent/ES2012556A6/en not_active Expired - Lifetime
- 1988-10-05 CH CH3702/88A patent/CH680002A5/fr not_active IP Right Cessation
- 1988-10-05 CN CN88109075A patent/CN1035845A/en active Pending
- 1988-10-06 GB GB8823448A patent/GB2210620B8/en not_active Expired - Fee Related
- 1988-10-06 IT IT8822213A patent/IT1227957B/en active
- 1988-10-06 JP JP63251011A patent/JPH02444A/en active Pending
- 1988-10-06 NZ NZ226486A patent/NZ226486A/en unknown

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1988005788A1 (en) *	1987-01-30	1988-08-11	Techne Corporation	Tranforming growth factor-beta
EP0290012A1 (en) *	1987-05-04	1988-11-09	Oncogen	TGF-B2 and novel compositions having anti-neoplastic activity

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Biochemistry 1987, 26, 2406-2410 EMBO 1987, 6, 1633-1636 *
DNA 1988, 7(1), 1-8 DNA 1988, 7(7), 493-498 *
J. Biol. Chem. 1987, 262, 1946-1949 Cell 1987, 48, 409-415 *
J. Cell. Biochem. Suppl. 12A) 1988 199 *

Also Published As

Publication number	Publication date
FR2621324B1 (en)	1994-02-18
BE1002693A5 (en)	1991-05-07
GB2210620A (en)	1989-06-14
GR1000492B (en)	1992-07-30
AT398433B (en)	1994-12-27
DE3833897C2 (en)	1997-03-20
FI884546A7 (en)	1989-04-07
NL8802442A (en)	1989-05-01
DK556388D0 (en)	1988-10-05
FI884546A0 (en)	1988-10-03
SE8803528D0 (en)	1988-10-05
SE8803528L (en)	1989-04-07
DK556388A (en)	1989-04-07
CN1035845A (en)	1989-09-27
MY103779A (en)	1993-09-30
CH680002A5 (en)	1992-05-29
NO884429L (en)	1989-04-07
ES2012556A6 (en)	1990-04-01
IE883018L (en)	1989-04-06
IE60918B1 (en)	1994-08-24
JPH02444A (en)	1990-01-05
IT1227957B (en)	1991-05-20
KR970001236B1 (en)	1997-02-04
DE3833897A1 (en)	1989-05-03
PT88670B (en)	1992-12-31
GB8823448D0 (en)	1988-11-16
NZ226486A (en)	1991-08-27
NO884429D0 (en)	1988-10-05
IT8822213A0 (en)	1988-10-06
KR890006814A (en)	1989-06-16
GB2210620B8 (en)	1995-07-17
FR2621324A1 (en)	1989-04-07
ATA245488A (en)	1994-04-15
IL87877A0 (en)	1989-03-31

Publication	Publication Date	Title
IL92737A0 (en)	1990-09-17	Cloning and expression of transforming growth factor beta-2
GB2202698B (en)	1991-12-11	Microfuse and method of manufacture
AU603967B2 (en)	1990-11-29	Triazone fertilizer and method of making
JPS6419093A (en)	1989-01-23	Production of abelmectine and culture therefor
AU1673888A (en)	1988-12-01	Cloning and expression of simian transforming growth factor- beta 1
IL83062A0 (en)	1987-12-31	Cloning and expression of acidic fibroblast growth
ZA886558B (en)	1989-04-26	Salbutamol-containing plaster and method of producing same
AU2498288A (en)	1989-05-18	Hybridoma and method of generating same
AU576717B2 (en)	1988-09-01	N6 - bicycloadenosines and methods of use
GB2210620B (en)	1992-07-08	Cloning and expression of transforming growth factor ¼2
AU2345188A (en)	1989-04-06	Cloning and expression of transforming growth factor 2b
ZA887007B (en)	1990-07-25	Cloning and expression of transforming growth factor b2
JPS6450846A (en)	1989-02-27	Arylbisperfluoroalkylcarbinol and manufacture of same
GB2191968B (en)	1990-01-31	Shelf structure and method of making same
AU1503888A (en)	1988-10-27	Method of producing iodine124 and meta-iodobenzlyguanidine containing iodine124
ZA899623B (en)	1990-09-26	Cloning and expression of transforming growth factor beta-2
GB2204313B (en)	1990-10-31	Novel bisbenzotrifluoride derivatives and method of preparing same
GB2197182B (en)	1990-09-05	Sleeve arrangement and method of manufacture thereof
AR244943A1 (en)	1993-12-30	Composition and method of stabilizing o-halopyridylphosphates
IE894030L (en)	1990-06-16	CLONING AND EXPRESSION OF GROWTH FACTOR ß2
ZA899032B (en)	1990-09-26	Cloning and expression of simian transforming growth factor-beta 1
ZA875048B (en)	1988-01-15	Cloning and expression of acidic fibroblast growth factor
JPS6470491A (en)	1989-03-15	Production of ethodolac and intermediate used therein
AU94791S (en)	1987-01-15	Set of forearm supports and blank
NZ232269A (en)	1991-09-25	Preparation of 4-demethoxy-daunomycinone and 4-demethoxy-7-deoxy-daunomycinone

Legal Events

Date	Code	Title	Description
1993-06-02	PCNP	Patent ceased through non-payment of renewal fee	Effective date: 19921008
1994-06-08	728C	Application made for restoration (sect. 28/1977)
1995-05-31	711H	Case decided by the comptr. ** correction allowed (sect. 117/1977)
1995-06-07	728A	Order made restoring the patent (sect. 28/1977)
1998-05-27	PCNP	Patent ceased through non-payment of renewal fee	Effective date: 19971006