GB2200845A - Teat-treating composition - Google Patents
Teat-treating composition Download PDFInfo
- Publication number
- GB2200845A GB2200845A GB08800357A GB8800357A GB2200845A GB 2200845 A GB2200845 A GB 2200845A GB 08800357 A GB08800357 A GB 08800357A GB 8800357 A GB8800357 A GB 8800357A GB 2200845 A GB2200845 A GB 2200845A
- Authority
- GB
- United Kingdom
- Prior art keywords
- composition
- water
- teat
- skin
- soluble component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 28
- 239000003139 biocide Substances 0.000 claims abstract description 11
- 239000000839 emulsion Substances 0.000 claims abstract description 10
- 230000003115 biocidal effect Effects 0.000 claims abstract description 5
- 230000002940 repellent Effects 0.000 claims abstract 2
- 239000005871 repellent Substances 0.000 claims abstract 2
- 239000007921 spray Substances 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 4
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims description 3
- 229960003260 chlorhexidine Drugs 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 230000008569 process Effects 0.000 claims description 3
- 150000003839 salts Chemical class 0.000 claims description 3
- FKPUYTAEIPNGRM-UHFFFAOYSA-N 1-(diaminomethylidene)guanidine;hydron;chloride Chemical compound [Cl-].N\C([NH3+])=N/C(N)=N FKPUYTAEIPNGRM-UHFFFAOYSA-N 0.000 claims description 2
- 239000003093 cationic surfactant Substances 0.000 claims description 2
- 239000012141 concentrate Substances 0.000 claims description 2
- 238000010790 dilution Methods 0.000 claims description 2
- 239000012895 dilution Substances 0.000 claims description 2
- 210000002445 nipple Anatomy 0.000 description 17
- 238000002360 preparation method Methods 0.000 description 11
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- 208000004396 mastitis Diseases 0.000 description 7
- 241000283690 Bos taurus Species 0.000 description 6
- IGFHQQFPSIBGKE-UHFFFAOYSA-N Nonylphenol Natural products CCCCCCCCCC1=CC=C(O)C=C1 IGFHQQFPSIBGKE-UHFFFAOYSA-N 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- SNQQPOLDUKLAAF-UHFFFAOYSA-N nonylphenol Chemical compound CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 5
- 239000003974 emollient agent Substances 0.000 description 5
- 235000011187 glycerol Nutrition 0.000 description 5
- 239000002480 mineral oil Substances 0.000 description 5
- 235000010446 mineral oil Nutrition 0.000 description 5
- 238000007598 dipping method Methods 0.000 description 4
- RARSHUDCJQSEFJ-UHFFFAOYSA-N p-Hydroxypropiophenone Chemical compound CCC(=O)C1=CC=C(O)C=C1 RARSHUDCJQSEFJ-UHFFFAOYSA-N 0.000 description 4
- 239000006071 cream Substances 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 239000002674 ointment Substances 0.000 description 3
- 235000012731 ponceau 4R Nutrition 0.000 description 3
- 239000004175 ponceau 4R Substances 0.000 description 3
- 230000000069 prophylactic effect Effects 0.000 description 3
- 238000005507 spraying Methods 0.000 description 3
- SWGJCIMEBVHMTA-UHFFFAOYSA-K trisodium;6-oxido-4-sulfo-5-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-2-sulfonate Chemical compound [Na+].[Na+].[Na+].C1=CC=C2C(N=NC3=C4C(=CC(=CC4=CC=C3O)S([O-])(=O)=O)S([O-])(=O)=O)=CC=C(S([O-])(=O)=O)C2=C1 SWGJCIMEBVHMTA-UHFFFAOYSA-K 0.000 description 3
- RWLALWYNXFYRGW-UHFFFAOYSA-N 2-Ethyl-1,3-hexanediol Chemical compound CCCC(O)C(CC)CO RWLALWYNXFYRGW-UHFFFAOYSA-N 0.000 description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 2
- NIQCNGHVCWTJSM-UHFFFAOYSA-N Dimethyl phthalate Chemical compound COC(=O)C1=CC=CC=C1C(=O)OC NIQCNGHVCWTJSM-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 230000002070 germicidal effect Effects 0.000 description 2
- 229910052740 iodine Inorganic materials 0.000 description 2
- 239000011630 iodine Substances 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- QFMDFTQOJHFVNR-UHFFFAOYSA-N 1-[2,2-dichloro-1-(4-ethylphenyl)ethyl]-4-ethylbenzene Chemical compound C1=CC(CC)=CC=C1C(C(Cl)Cl)C1=CC=C(CC)C=C1 QFMDFTQOJHFVNR-UHFFFAOYSA-N 0.000 description 1
- RFVNOJDQRGSOEL-UHFFFAOYSA-N 2-hydroxyethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCO RFVNOJDQRGSOEL-UHFFFAOYSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000031462 Bovine Mastitis Diseases 0.000 description 1
- RTMBGDBBDQKNNZ-UHFFFAOYSA-L C.I. Acid Blue 3 Chemical compound [Ca+2].C1=CC(N(CC)CC)=CC=C1C(C=1C(=CC(=C(O)C=1)S([O-])(=O)=O)S([O-])(=O)=O)=C1C=CC(=[N+](CC)CC)C=C1.C1=CC(N(CC)CC)=CC=C1C(C=1C(=CC(=C(O)C=1)S([O-])(=O)=O)S([O-])(=O)=O)=C1C=CC(=[N+](CC)CC)C=C1 RTMBGDBBDQKNNZ-UHFFFAOYSA-L 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 229920002413 Polyhexanide Polymers 0.000 description 1
- HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 description 1
- 241000186064 Trueperella pyogenes Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 235000013365 dairy product Nutrition 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- FBSAITBEAPNWJG-UHFFFAOYSA-N dimethyl phthalate Natural products CC(=O)OC1=CC=CC=C1OC(C)=O FBSAITBEAPNWJG-UHFFFAOYSA-N 0.000 description 1
- 229960001826 dimethylphthalate Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000036074 healthy skin Effects 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000004530 micro-emulsion Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 239000008239 natural water Substances 0.000 description 1
- 231100000344 non-irritating Toxicity 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 235000012736 patent blue V Nutrition 0.000 description 1
- 239000004177 patent blue V Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 235000019271 petrolatum Nutrition 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 230000000246 remedial effect Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 230000001235 sensitizing effect Effects 0.000 description 1
- 230000005808 skin problem Effects 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0041—Mammary glands, e.g. breasts, udder; Intramammary administration
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A teat-treating composition comprises a biocide and an emulsion of a non-water-soluble component e.g. a skin conditioner or fly repellent.
Description
"TEAT-TREATING COMPOSITIONS, PRODUCTION AND USE THEREOF."
This invention relates to teat-treating compositions, to the production thereof and to the use thereof; more particularly, it relates to teat dips or sprays.
For many years, in particular cows' teats have been sanitised immediately after milking in order to reduce the incidence of mastitis. This is generally carried out by either dipping or spraying the teats. Mastitis is a condition of microbiological colonisation of cows' milking organs. If contamination reaches a sufficiently high level due to either challenge or microbial growth, the clinical symptoms of mastitis become evident resulting, inter alia, in the additional expense to a farmer of milk loss and veterinary treatment. (This represents the largest field of interest, but the present compositions may also be used on other animals.)
Known bovine teat dip or spray preparations include many biocidal agents, such as chlorine, iodine and chlorhexidine.The use of such biocides, which in some instances may be irritant to skin, together with other factors, notably climatic conditions, necessitate the incorporation of emollients in bovine teat dips and sprays in order to maintain a good healthy skin condition.
Good teat skin condition is essential in order to promote the natural immune response defence mechanisms against bacterial contamination and hence to reduce the incidence of mastitis. Good skin condition is widely recognised as being promoted by the retention of moisture in the skin. This is normally achieved in teat dips or sprays by the inclusion of humectant materials, such as glycerine, a water-soluble hygroscopic compound. The function of such materials is to remain on or near the surface of the skin and to absorb water from the atmosphere to compensate for the natural water loss through the skin.
This process works perfectly adequately in the majority of circumstances, but may work in reverse, causing drying of the skin, particularly in very dry atmospheres or during hot summers.
It is possible to promote good skin condition by another mechanism whereby the loss of water to the atmosphere is prevented or considerably reduced. In order to achieve this, the skin must be coated with a non-watersoluble material, such as petroleum jelly. There are many preparations available to farmers for this purpose - such as salves or creams, and these are used in a remedial manner, i.e. only onanimals with specific skin problems.
It is impractical to use creams or salves on all cows in a prophylactic mode because of high use rates and consequent high cost. They are also not easily applied.
A surprising advantageous new method of applying nonwater-soluble components for the prevention of water loss from the skin has now been discovered. An emulsions of a non-water-soluble component has now been prepared in a teat treating composition which is sufficiently mobile to enable easy application in a prophylactic manner by either dipping or spraying.
In a main embodiment, the present invention relates to a teat dip or spray which is a prophylactic preparation for use as an aid in the control of mastitis in dairy cattle comprising an. efficacious level of biocide in combination with either an emulsion of a non-water-soluble component alone or a mixture of a non-water-soluble component in emulsion form with a water-soluble component, which preparation is primarily for the purpose of producing good skin condition and which is in a physical form which is both stable and capable of economic use.
The present invention provides a teat-treating composition which comprises a biocide and an emulsion of a non-water-soluble component, such as a skin-conditioner.
Such may be produced by conventional means. The present invention also relates thereto.
The use of the present compositions is also encompassed.
Such emulsions may be either clear, i.e. micro emulsions, or opaque in the more usual manner. More than sufficient quantities of non-water-soluble component(s) may be incorporated to give excellent skin condition. The present compositions also have a unique combination of other desirable advantageous properties including: (1) The emulsions, whether clear or opaque, will not
precipitate on standing, exhibit good long term
stability and do not require agitation prior to use.
(2) The ennilsions, whether clear or opaque, are substantially free
of inorganic salts and therefore will not leave or
deposit a source of irritation on the teat skin
after application, for example by dipping.
(3) The viscosity characteristics of the preparations
are such that the use rate is not excessive and any
excess will readily run off, even in cold weather,
but not so rapidly that absorption or penetration of
the germicidal components and emollients is reduced
to an ineffective level, hence sufficient germicidal andskin conditioning components are retained on the
skin in order to promote the desirable soft, supple
skin condition necessary for good udder health.
(4) The preparations are non-irritating and non
sensitising either to animals or to humans.
(5) The pH of the preparations is preferably within
the range of from 3 to 6, i.e. very close to that
of the skin.
According to the present invention the teat-treating compositions may be in either concentrate form (for later dilution with water) or ready-to-use form. In the latter case, a composition in the form of a dip or spray, for example, would preferably have the viscosity of from 10 to 500 centistokes.
As will be appreciated by those skilled in the art, various conventional biocides, especially cationics, are suitable for use in accordance with the.present invention.
They are commonly used in addition to the emulsified skinconditioning component. Examples include chlorhexidine, which may be in salt form, and "PMBH" (polymeric biguanide hydrochloride), as well as cationic surfactant biocides.
The following is provided by way of illustration:
Example 1 wt %
Chlorhexidine digluconate 2.25%
Propan-2-ol 5.00%
Mineral oil WOM.14 4.00% C13-15 alcohol 3 E.O. 1.03%
Nonyl phenol 8 E.O. 0.38%
Edicol ponceau 4R 0.0013%
Glycerine 6.00%
Water 81.34%
Teat skin condition is a major factor in the prevention of bovine mastitis. Dried, cracked or sore teats becpme readily infected and are a constant problem, particularly in cold weather. This condition may be rectified by the use of creams and salves, but in order to prevent deterioration of skin condition it has been found to be efficacious to employ higher levels of emollients than normal in adverse climatic conditions. Such preparatidns as in Example l for instance have also been found to be therapeutic and will rapidly restore dried and cracked teats to good condition. Thus, the present invention provides preparations which are efficacious in hot and cold climatic conditions and which retain the necessary low viscosity and high stability.
Example 2 wt %
Chlorhexidine digluconate 2.25%
Propan-2-ol 5.00%
Mineral oil OM.14 4.00% C1-15 alcohol 3 E.O. 1.03%
Nonyl phenol 8 E.O. 0.38 Edicol ponceau 4R 0.0013%
Glycerine 3.00%
2-ethyl-1,3-hexanediol 0. 50% Dimethyl phthalate 0.50%
Water 83.34%
A particularly virulent form of mastitis is the so-called "Summer Mastitis", also known as "August bag". This condition is vectored by flies, often involving the bacterium Corynebacterium Pyogenes as one of the infecting species. In order -to prevent the deposit of bacteria by flies, it is no use simply to incorporateaninsecticide into a preparation, but rather it is necessary to use a fly repellant.There are a number of fly repellant materials generally available which may be used to good effect incorporated into a prophylactic treatment applied to the teats. Generally, however, these materials are not water-soluble. In accordance with the present invention it has been found that fly repellant materials, such as 2-ethyl1,3-hexanediol, may be incorporated into a teat dip or spray admixture with the non-water-soluble component of the emulsions. The above formulation is one such example. Such may be produced by mixing.
Example 3 wt %
Chlorhexidine digluconate ;25 Propan-2-ol 5.00%
Mineral oil WOM.14 4.00% C13-15 alcohol 3 E.O. 1.03%
Nonyl phenol 8 E.O. 0.38%
Edicol ponceau 4R 0.0013%
Water 87.34%
For general use, the oil phase alone has sufficient emollient properties to give an efficacious teat dip or spray preparation. Example 3 is typical of the type of preparation which has been found to give excellent skin condition with the oil acting as an emollient and as a barrier to prevent moisture loss from the teat skin according to the manner described above.
Example 4 wt % Polyhexamethylene biguanide hydrochloride 4%
Mineral oil 2%
Propan-2-ol 5% Cl3-l5 alcohol 3 E.O. 1.5% Nonyl phenol 8 E.O. 0.55%
Glycerine 3%
Patent Blue V 0.005%
Water to 100%
Example 5 wt %
Iodine 28%
) - Complex
Nonyl Phenol 12 E.O. 72% ) 1.0% (to 2000
ppm) C13-15 alcohol 3 E.O. 3.68%
Nonyl Phenol 8 E.O. 1.48%
Mineral Oil 7.4%
Water to 100%
Examples 4 and 5 illustrate the use of the present emulsion system with other biocides. Occasionally, minor adjustments in the emulsifier system may be desirable to stabilise the formulation, Such is within the competence of those skilled in the art. In all cases, the product has a low viscosity particularly suitable for dipping and spraying and has the high stability necessary for a prolonged shelf life.
Example 6 wt%
WOM 14 2%
PEG 600 monostearate 1.07%
Crill 3 0.43%
Glycerine 3.0%
Ethylan CPG 7545 0.5%
Imsol A 5%
Chlorhexidine digluconate B.P. 2.25%
Water 85.75%
Although the formulation may be regarded as -a little - more difficult to produce in that heat is required to solubilise the components, stability is good at high temperature and such a product would -be particularly useful in hot countries.
Claims (13)
1. A teat-treating composition which comprises a biocide and an emulsion of a non-water-soluble component.
2. A composition as claimed in claim 1 wherein the non-water-soluble component comprises a skinconditioner.
3. A composition as claimed in claim 1 or claim 2 wherein the non-water-soluble component comprises a fly repellent.
4. A composition as claimed in any of claims 1 to 3 wherein the biocide is selected from chlorhexidine and salts thereof, polymeric biguanide hydrochloride and cationic surfactant biocides.
5. A composition as claimed in any of claims 1 to 4 wherein it is transparent, translucent or opaque.
6. A composition as claimed in any of claims 1 to 5 wherein it is in the form of a concentrate for dilution.
7. A composition as claimed in any of claims 1 to 5 wherein it is in diluted ready-to-use form.
8. A composition as claimed in claim 7 wherein the viscosity is from 10 to 500 centistokes.
9. A composition as claimed in any of claims 1 to 8 wherein it is in the form of a dip or spray.
10. A composition as claimed in any of claims 1 to 9 wherein the stability is extended to higher temperatures.
11. A composition as claimed in any of claims 1 to 10 substantially as herein described with particular reference to the Examples.
12. A process for the production of a composition as claimed in any of claims 1 to 11 substantially as herein described with particular reference to the Examples.
13. The use of a composition as claimed in any of claims 1 to 11 or produced by a process as claimed in claim 12 substantially as herein described with particular reference to the Examples.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878700466A GB8700466D0 (en) | 1987-01-09 | 1987-01-09 | Teat-treating compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB8800357D0 GB8800357D0 (en) | 1988-02-10 |
| GB2200845A true GB2200845A (en) | 1988-08-17 |
| GB2200845B GB2200845B (en) | 1990-06-13 |
Family
ID=10610469
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB878700466A Pending GB8700466D0 (en) | 1987-01-09 | 1987-01-09 | Teat-treating compositions |
| GB8800357A Expired - Lifetime GB2200845B (en) | 1987-01-09 | 1988-01-08 | "teat-treating emulsions". |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB878700466A Pending GB8700466D0 (en) | 1987-01-09 | 1987-01-09 | Teat-treating compositions |
Country Status (1)
| Country | Link |
|---|---|
| GB (2) | GB8700466D0 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0356264A3 (en) * | 1988-08-22 | 1991-03-06 | Becton, Dickinson and Company | Cleansing composition for topical disinfection |
| EP0696353A4 (en) * | 1993-04-28 | 1998-01-21 | Environmental Test Systems | Method and device for the determination of polymeric biguanides in aqueous fluids |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1525441A (en) * | 1977-03-11 | 1978-09-20 | Jeyes Group Ltd | Thickened disinfectants |
| GB1554615A (en) * | 1977-04-07 | 1979-10-24 | Wilson E S | Quaternary ammonium ammonium compound teat dips |
| EP0030576A1 (en) * | 1978-09-22 | 1981-06-24 | Masti-Kure Products Co., Inc. | Film-forming alcoholic microbicidal teat dip and method of use thereof |
| EP0032031A2 (en) * | 1979-12-26 | 1981-07-15 | Merck & Co. Inc. | Use of polyamine compounds in prevention of mastitis |
| GB2121279A (en) * | 1982-05-25 | 1983-12-21 | Edward Sturdy Wilson | Quaternary ammonium compound disinfectants for use in bovine mastitis |
-
1987
- 1987-01-09 GB GB878700466A patent/GB8700466D0/en active Pending
-
1988
- 1988-01-08 GB GB8800357A patent/GB2200845B/en not_active Expired - Lifetime
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1525441A (en) * | 1977-03-11 | 1978-09-20 | Jeyes Group Ltd | Thickened disinfectants |
| GB1554615A (en) * | 1977-04-07 | 1979-10-24 | Wilson E S | Quaternary ammonium ammonium compound teat dips |
| EP0030576A1 (en) * | 1978-09-22 | 1981-06-24 | Masti-Kure Products Co., Inc. | Film-forming alcoholic microbicidal teat dip and method of use thereof |
| EP0032031A2 (en) * | 1979-12-26 | 1981-07-15 | Merck & Co. Inc. | Use of polyamine compounds in prevention of mastitis |
| GB2121279A (en) * | 1982-05-25 | 1983-12-21 | Edward Sturdy Wilson | Quaternary ammonium compound disinfectants for use in bovine mastitis |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0356264A3 (en) * | 1988-08-22 | 1991-03-06 | Becton, Dickinson and Company | Cleansing composition for topical disinfection |
| EP0696353A4 (en) * | 1993-04-28 | 1998-01-21 | Environmental Test Systems | Method and device for the determination of polymeric biguanides in aqueous fluids |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2200845B (en) | 1990-06-13 |
| GB8700466D0 (en) | 1987-02-11 |
| GB8800357D0 (en) | 1988-02-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 732E | Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20060108 |