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GB2282811B - Vaccine for the prevention of porcine reproductive and respiratory syndrome - Google Patents

Vaccine for the prevention of porcine reproductive and respiratory syndrome

Info

Publication number
GB2282811B
GB2282811B GB9418775A GB9418775A GB2282811B GB 2282811 B GB2282811 B GB 2282811B GB 9418775 A GB9418775 A GB 9418775A GB 9418775 A GB9418775 A GB 9418775A GB 2282811 B GB2282811 B GB 2282811B
Authority
GB
United Kingdom
Prior art keywords
vaccine
prevention
respiratory syndrome
porcine reproductive
porcine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB9418775A
Other versions
GB2282811A (en
GB9418775D0 (en
Inventor
Duran Juan Plana
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Farma SA
Original Assignee
Cyanamid Iberica SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cyanamid Iberica SA filed Critical Cyanamid Iberica SA
Publication of GB9418775D0 publication Critical patent/GB9418775D0/en
Publication of GB2282811A publication Critical patent/GB2282811A/en
Application granted granted Critical
Publication of GB2282811B publication Critical patent/GB2282811B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10051—Methods of production or purification of viral material
    • C12N2770/10052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GB9418775A 1993-09-17 1994-09-16 Vaccine for the prevention of porcine reproductive and respiratory syndrome Expired - Lifetime GB2282811B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9301973A ES2074950B1 (en) 1993-09-17 1993-09-17 VACCINE FOR THE PREVENTION OF REPRODUCTIVE AND RESPIRATORY DISEASE OF THE SOW.

Publications (3)

Publication Number Publication Date
GB9418775D0 GB9418775D0 (en) 1994-11-02
GB2282811A GB2282811A (en) 1995-04-19
GB2282811B true GB2282811B (en) 1998-02-18

Family

ID=8283072

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9418775A Expired - Lifetime GB2282811B (en) 1993-09-17 1994-09-16 Vaccine for the prevention of porcine reproductive and respiratory syndrome

Country Status (7)

Country Link
DE (1) DE4432338C2 (en)
DK (1) DK173128B1 (en)
ES (1) ES2074950B1 (en)
FR (1) FR2709966B1 (en)
GB (1) GB2282811B (en)
IT (1) IT1267448B1 (en)
NL (1) NL194940C (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013152086A1 (en) 2012-04-04 2013-10-10 Zoetis Llc Pcv/mycoplasma hyopneumoniae/prrs combination vaccine
WO2013152083A2 (en) 2012-04-04 2013-10-10 Zoetis Llc Pcv/mycoplasma hyopneumoniae combination vaccine
WO2013152081A1 (en) 2012-04-04 2013-10-10 Zoetis Llc Mycoplasma hyopneumoniae vaccine

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA27788C2 (en) * 1991-06-06 2000-10-16 Стіхтінг Сентрал Діргенескюндіг Інстітют Composition comprising the causative lelystad agent, vaccine composition for animal vaccination (variants) and diagnostic kit for antibody detection
US6042830A (en) * 1992-08-05 2000-03-28 Boehringer Ingelheim Vetmedica, Inc. Viral agent associated with mystery swine disease
US6773908B1 (en) 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US5695766A (en) 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US6380376B1 (en) 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6251397B1 (en) * 1992-10-30 2001-06-26 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus and immunogenic compositions containing the same
ES2078187B1 (en) * 1994-05-13 1996-07-16 Cynamid Iberica S A RECRS COMBINANT PROTEINS, DIAGNOSTIC KITS AND VACCINES CONTAINING SUCH RECOMBINANT PROTEINS.
DK53595A (en) * 1994-05-13 1995-11-14 Iberica Cyanamid Recombinant PRRSV proteins, diagnostic kits and vaccines containing such recombinant PRRSV proteins
US5690940A (en) * 1995-06-21 1997-11-25 Regents Of The University Of Minnesota Low pathogencity PRRS live virus vaccines and methods of preparation thereof
US5866401A (en) * 1996-03-01 1999-02-02 Schering Corporation Porcine reproductive and respiratory syndrome vaccine
BR9708443B1 (en) 1996-03-01 2012-06-12 vaccine against reproductive and respiratory syndrome in pigs.
EP0839912A1 (en) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
HU228704B1 (en) 1997-05-06 2013-05-28 Boehringer Ingelheim Vetmed Prrsv antigenic sites identifying peptide sequences of prrs virus for use in vaccines or diagnostic assays
UA78180C2 (en) 1997-10-03 2007-03-15 Меріаль Porcine circovirus, vaccines and diagnostic reagents
NZ501264A (en) 1998-12-22 2001-09-28 Pfizer Prod Inc Polynucleotide DNA sequence encoding an infectious RNA molecule encoding a North American PRRS
JP3961222B2 (en) 1999-03-08 2007-08-22 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー PRRSV vaccine
ATE474041T1 (en) 1999-04-22 2010-07-15 Us Agriculture VACCINE BASED ON ISOLATE JA-142 AGAINST REPRODUCTIVE AND RESPIRATORY SYNDROME IN SWINE
RU2232596C1 (en) * 2002-10-16 2004-07-20 Федеральное государственное учреждение Всероссийский научно-исследовательский институт защиты животных Method for manufacturing virus vaccine against porcine reproductive-respiratory syndrome
CA2571452A1 (en) 2004-06-18 2006-01-26 Regents Of The University Of Minnesota Identifying virally infected and vaccinated organisms
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
ES2532861T3 (en) 2004-12-30 2015-04-01 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions for PCV2 for use in a method of preventing a PCV2 infection
UA95778C2 (en) 2005-06-24 2011-09-12 Риджентс Оф Зе Юниверсити Оф Миннесота Prrs viruses, infectious clones, mutants thereof, and methods of use
PL1968630T3 (en) 2005-12-29 2018-08-31 Boehringer Ingelheim Vetmedica, Inc. Multivalent pcv2 immunogenic compositions
RU2316346C2 (en) * 2006-02-20 2008-02-10 Федеральное государственное учреждение "Федеральный центр охраны здоровья животных" (ФГУ "ВНИИЗЖ") Inactivated emulsion vaccine against swine's reproductive-respiratory syndrome
TWI627281B (en) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 Methods of reducing viricidal activity in pcv-2 compositions and pcv-2 compositions with an improved immunogenicity
DK2558118T3 (en) * 2010-04-16 2019-08-26 Univ Gent ANIMAL PROTECTIVE VACCINE AGAINST PIG REProduction and Respiratory Syndrome Virus
WO2012110490A1 (en) 2011-02-17 2012-08-23 Boehringer Ingelheim Vetmedica Gmbh Commercial scale process for production of prrsv
ES2550258T3 (en) 2011-02-17 2015-11-05 Boehringer Ingelheim Vetmedica Gmbh New strain of the European PRRSV
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
EP2737058A1 (en) 2011-07-29 2014-06-04 Boehringer Ingelheim Vetmedica GmbH INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
EP2968513A2 (en) 2013-03-15 2016-01-20 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
ES2940691T3 (en) 2013-12-20 2023-05-10 Boehringer Ingelheim Vetmedica Gmbh PRRS virus variant, European PRRS virus cDNA clone and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992021375A1 (en) * 1991-06-06 1992-12-10 Stichting Centraal Diergeneeskundig Instituut Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
WO1993007898A1 (en) * 1991-10-14 1993-04-29 Akzo Nobel N.V. Porcine reproductive respiratory syndrome vaccine and diagnostic
WO1994018311A1 (en) * 1993-02-08 1994-08-18 Bayer Corporation Process for growing porcine reproductive and respiratory syndrome virus and its use in vaccines

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686097B1 (en) * 1992-01-14 1994-12-30 Rhone Merieux PREPARATION OF ANTIGENS AND MYSTERY DISEASE VIRUS VACCINES, ANTIGENS AND VACCINES OBTAINED FOR THE PREVENTION OF THIS DISEASE.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992021375A1 (en) * 1991-06-06 1992-12-10 Stichting Centraal Diergeneeskundig Instituut Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
WO1993007898A1 (en) * 1991-10-14 1993-04-29 Akzo Nobel N.V. Porcine reproductive respiratory syndrome vaccine and diagnostic
WO1994018311A1 (en) * 1993-02-08 1994-08-18 Bayer Corporation Process for growing porcine reproductive and respiratory syndrome virus and its use in vaccines

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Virology 1993,193,329-339 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013152086A1 (en) 2012-04-04 2013-10-10 Zoetis Llc Pcv/mycoplasma hyopneumoniae/prrs combination vaccine
WO2013152083A2 (en) 2012-04-04 2013-10-10 Zoetis Llc Pcv/mycoplasma hyopneumoniae combination vaccine
WO2013152081A1 (en) 2012-04-04 2013-10-10 Zoetis Llc Mycoplasma hyopneumoniae vaccine
EP3508218A1 (en) 2012-04-04 2019-07-10 Zoetis Services LLC Pcv/mycoplasma hyopneumoniae combination vaccine
EP3508217A1 (en) 2012-04-04 2019-07-10 Zoetis Services LLC Pcv/mycoplasma hyopneumoniae/prrs combination vaccine
EP4039271A1 (en) 2012-04-04 2022-08-10 Zoetis Services LLC Mycoplasma hyopneumoniae vaccine

Also Published As

Publication number Publication date
NL194940C (en) 2003-08-04
ITTO940713A1 (en) 1996-03-09
ES2074950A1 (en) 1995-09-16
NL9401414A (en) 1995-04-18
GB2282811A (en) 1995-04-19
DE4432338A1 (en) 1995-05-04
DK173128B1 (en) 2000-01-31
GB9418775D0 (en) 1994-11-02
ES2074950B1 (en) 1996-03-16
DE4432338C2 (en) 1997-10-30
DK102894A (en) 1995-03-18
ITTO940713A0 (en) 1994-09-09
IT1267448B1 (en) 1997-02-05
FR2709966B1 (en) 1997-05-23
NL194940B (en) 2003-04-01
FR2709966A1 (en) 1995-03-24

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)

Free format text: REGISTERED BETWEEN 20140123 AND 20140129

PE20 Patent expired after termination of 20 years

Expiry date: 20140915