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GB2248186A - Preparation of vaccines - Google Patents

Preparation of vaccines

Info

Publication number
GB2248186A
GB2248186A GB9120825A GB9120825A GB2248186A GB 2248186 A GB2248186 A GB 2248186A GB 9120825 A GB9120825 A GB 9120825A GB 9120825 A GB9120825 A GB 9120825A GB 2248186 A GB2248186 A GB 2248186A
Authority
GB
United Kingdom
Prior art keywords
vaccine
prepared
bacterial cells
phase containing
vaccines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB9120825A
Other versions
GB9120825D0 (en
GB2248186B (en
Inventor
Afshaw Ahmad
Alexander Buchan
Gordon Robert Bruce Skinner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Research International Ltd Great Britain
Original Assignee
Medical Research International Ltd Great Britain
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Research International Ltd Great Britain filed Critical Medical Research International Ltd Great Britain
Publication of GB9120825D0 publication Critical patent/GB9120825D0/en
Publication of GB2248186A publication Critical patent/GB2248186A/en
Application granted granted Critical
Publication of GB2248186B publication Critical patent/GB2248186B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A vaccine is prepared by incubating a suspension of peptidoglycan containing bacteria with Lysostaphin for a period of time sufficient to digest a substantial proportion of the bacterial cells, subjecting the treated material to mechanical, for example ultrasonic, disruption, separating the resulting material, preferably by centrifugation into a solid phase containing any live or killed bacterial cells and a supernatant liquid phase containing bacterial antigens and collecting the vaccine prepared.
GB9120825A 1989-03-23 1991-09-23 Preparation of vaccines Expired - Fee Related GB2248186B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898906794A GB8906794D0 (en) 1989-03-23 1989-03-23 Preparation of vaccines

Publications (3)

Publication Number Publication Date
GB9120825D0 GB9120825D0 (en) 1991-12-04
GB2248186A true GB2248186A (en) 1992-04-01
GB2248186B GB2248186B (en) 1993-04-28

Family

ID=10653942

Family Applications (2)

Application Number Title Priority Date Filing Date
GB898906794A Pending GB8906794D0 (en) 1989-03-23 1989-03-23 Preparation of vaccines
GB9120825A Expired - Fee Related GB2248186B (en) 1989-03-23 1991-09-23 Preparation of vaccines

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB898906794A Pending GB8906794D0 (en) 1989-03-23 1989-03-23 Preparation of vaccines

Country Status (4)

Country Link
AU (1) AU5273890A (en)
BR (1) BR9007246A (en)
GB (2) GB8906794D0 (en)
WO (1) WO1990011088A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9110808D0 (en) * 1991-05-17 1991-07-10 Retroscreen Ltd Aids vaccine and method for its production
US7943352B2 (en) * 2006-03-29 2011-05-17 Bacoustics, Llc Apparatus and methods for vaccine development using ultrasound technology

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0302781A1 (en) * 1987-08-03 1989-02-08 Institut Pasteur Process for obtaining staphylococcal capsule polysaccharides, uses of these polysaccharides and strains for putting this process into operation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0302781A1 (en) * 1987-08-03 1989-02-08 Institut Pasteur Process for obtaining staphylococcal capsule polysaccharides, uses of these polysaccharides and strains for putting this process into operation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Infection and Immunity, Vol.56,No.5,May 1988, pages 1061-5, A.L. Cheung et al.: *
The Merck Index, tenth edition, 1983, page 5459 *

Also Published As

Publication number Publication date
GB8906794D0 (en) 1989-05-10
AU5273890A (en) 1990-10-22
GB9120825D0 (en) 1991-12-04
GB2248186B (en) 1993-04-28
BR9007246A (en) 1992-02-25
WO1990011088A1 (en) 1990-10-04

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19950321