[go: up one dir, main page]

GB2108528B - Process for preparing sub-culturable lymphokine-producing human t cell hybridomas - Google Patents

Process for preparing sub-culturable lymphokine-producing human t cell hybridomas

Info

Publication number
GB2108528B
GB2108528B GB08230526A GB8230526A GB2108528B GB 2108528 B GB2108528 B GB 2108528B GB 08230526 A GB08230526 A GB 08230526A GB 8230526 A GB8230526 A GB 8230526A GB 2108528 B GB2108528 B GB 2108528B
Authority
GB
United Kingdom
Prior art keywords
culturable
lymphokine
producing human
cell hybridomas
preparing sub
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08230526A
Other versions
GB2108528A (en
Inventor
Toshiaki Osawa
Yoshiro Kobayashi
Makoto Asada
Masahiro Higuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Denka Co Ltd
Original Assignee
Denki Kagaku Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Denki Kagaku Kogyo KK filed Critical Denki Kagaku Kogyo KK
Publication of GB2108528A publication Critical patent/GB2108528A/en
Application granted granted Critical
Publication of GB2108528B publication Critical patent/GB2108528B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
GB08230526A 1981-10-28 1982-10-26 Process for preparing sub-culturable lymphokine-producing human t cell hybridomas Expired GB2108528B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56171505A JPS6011889B2 (en) 1981-10-28 1981-10-28 Passageable lymphokine-producing human T cell fusion line and method for obtaining the same

Publications (2)

Publication Number Publication Date
GB2108528A GB2108528A (en) 1983-05-18
GB2108528B true GB2108528B (en) 1984-12-19

Family

ID=15924347

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08230526A Expired GB2108528B (en) 1981-10-28 1982-10-26 Process for preparing sub-culturable lymphokine-producing human t cell hybridomas

Country Status (5)

Country Link
JP (1) JPS6011889B2 (en)
CA (1) CA1202917A (en)
DE (1) DE3239863C2 (en)
FR (1) FR2515208B1 (en)
GB (1) GB2108528B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1214123A (en) * 1983-01-20 1986-11-18 Masashi Matsui Cell lines for use in the preparation of hybridoma cells
JPS59169492A (en) * 1983-03-15 1984-09-25 Asahi Chem Ind Co Ltd Production of biologically active substance from human fused cells
ATE48617T1 (en) * 1984-04-13 1989-12-15 Litton Bionetics Inc LEUKOREGULIN, AN ANTITUMOR LYMPHOCINE AND ITS USE AS A CURE.
US4843004A (en) * 1984-05-11 1989-06-27 Sloan-Kettering Institute For Cancer Research Method for the production of human T-T cell hybrids and production suppressor factor by human T-T cell hybrids
US4959457A (en) * 1984-05-31 1990-09-25 Genentech, Inc. Anti-lymphotoxin
US4665032A (en) * 1984-06-28 1987-05-12 Cornell Research Foundation, Inc. Human T cell hybridomas which produce immunosuppressive factors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0057107A3 (en) * 1981-01-28 1982-11-10 Coats Patons Plc Method of manufacturing monoclonal antibodies and cells capable of manufacturing such antibodies

Also Published As

Publication number Publication date
FR2515208B1 (en) 1985-07-19
CA1202917A (en) 1986-04-08
FR2515208A1 (en) 1983-04-29
GB2108528A (en) 1983-05-18
JPS5872520A (en) 1983-04-30
JPS6011889B2 (en) 1985-03-28
DE3239863A1 (en) 1983-05-05
DE3239863C2 (en) 1985-08-29

Similar Documents

Publication Publication Date Title
PT74504B (en) Process for preparing imidazodiazepines
PT74395B (en) Process for preparing acrylate-maleate copolymer
DE3269855D1 (en) Process for cell disruption
DE3266550D1 (en) Process for preparing polyisocyanates
YU149482A (en) Process for obtaining amido-benzamides
YU43084B (en) Process for obtaining s-benzylthiocarbamates
DE3268413D1 (en) Process for preparing chlorotrifluoromethylbenzene
DE3261535D1 (en) Process for preparing aryldiazosulphonates
PT75680A (en) Process for preparing 5-phenyl-2s-pentanol
GB2108528B (en) Process for preparing sub-culturable lymphokine-producing human t cell hybridomas
DE3261580D1 (en) Process for preparing 4-haloazetidin-2-ones
YU125882A (en) Process for obtaining imidazolyl-propionitrile
PL239428A1 (en) Process for preparing pyrbuterol
YU43789B (en) Process for obtaining azaspiro-alcandione
DE3262826D1 (en) Process for preparing m-alkylhydroxybenzene
DE3267381D1 (en) Process for preparing beta-chloroalanine
GB2112777B (en) Process for preparing mononitrochlorobenzene
DE3263884D1 (en) Process for preparing alpha-omega-bis-flurosulfato-perfluoroalkanes
DE3260739D1 (en) Process for making 2-carbalkoxy-5-carboxynitrobenzenes
DE3260363D1 (en) Process for preparing 3-alkylaminophenols
DE3260668D1 (en) Process for preparing butadienedinitriles
DE3263400D1 (en) Process for preparing trialkylsilyldiazomethanes
YU78481A (en) Process for preparing beta-methyldigoxin
PL233368A2 (en) Process for preparing 1-substituted-2-oxabenzocycloalkanes
PL232438A1 (en) Process for preparing polydesoxynucleotides

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19951026