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GB2105323B - Aporphine compounds - Google Patents

Aporphine compounds

Info

Publication number
GB2105323B
GB2105323B GB08217644A GB8217644A GB2105323B GB 2105323 B GB2105323 B GB 2105323B GB 08217644 A GB08217644 A GB 08217644A GB 8217644 A GB8217644 A GB 8217644A GB 2105323 B GB2105323 B GB 2105323B
Authority
GB
United Kingdom
Prior art keywords
aporphine compounds
aporphine
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08217644A
Other versions
GB2105323A (en
Inventor
John L Neumeyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Northeastern University China
Original Assignee
Northeastern University China
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/379,557 external-priority patent/US4543256A/en
Application filed by Northeastern University China filed Critical Northeastern University China
Publication of GB2105323A publication Critical patent/GB2105323A/en
Application granted granted Critical
Publication of GB2105323B publication Critical patent/GB2105323B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06Peri-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/18Ring systems of four or more rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB08217644A 1981-06-18 1982-06-18 Aporphine compounds Expired GB2105323B (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US27477281A 1981-06-18 1981-06-18
US34684182A 1982-02-08 1982-02-08
US35891782A 1982-03-17 1982-03-17
US35891882A 1982-03-17 1982-03-17
US06/379,557 US4543256A (en) 1982-03-17 1982-05-18 (-)-10,1L Methylenedioxy-N-N-propylnoraporphine and methods employing it for inhibiting the effects of epileptic seizures and for prevention and treatment of duodenal ulcers

Publications (2)

Publication Number Publication Date
GB2105323A GB2105323A (en) 1983-03-23
GB2105323B true GB2105323B (en) 1985-12-11

Family

ID=27540584

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08217644A Expired GB2105323B (en) 1981-06-18 1982-06-18 Aporphine compounds

Country Status (8)

Country Link
CA (1) CA1270253A (en)
DE (1) DE3222840A1 (en)
DK (1) DK272182A (en)
FR (1) FR2508043B1 (en)
GB (1) GB2105323B (en)
IE (1) IE53161B1 (en)
IT (1) IT1191200B (en)
NL (1) NL8202467A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990012574A1 (en) * 1989-04-25 1990-11-01 Northeastern University Dopamine agonist compounds
AU4536599A (en) 1999-06-21 2001-01-09 Geochemistry Research Limited Metal-rich silica products from geothermal and synthetic aqueous systems nen wie
US9359303B2 (en) 2009-04-21 2016-06-07 Purdue Research Foundation Octahydrobenzoisoquinoline modulators of dopamine receptors and uses therefor
WO2020070099A1 (en) 2018-10-02 2020-04-09 H. Lundbeck A/S Administration of catecholamine prodrugs in combination with a 5-ht2b antagonist

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717643A (en) * 1967-05-04 1973-02-20 Sterling Drug Inc N-substituted-norapomorphines
US3810987A (en) * 1972-06-12 1974-05-14 Merck & Co Inc Blood pressure lowering method using an aporphine

Also Published As

Publication number Publication date
IT8267776A1 (en) 1984-06-09
FR2508043B1 (en) 1987-04-30
DK272182A (en) 1982-12-19
GB2105323A (en) 1983-03-23
IE821441L (en) 1982-12-18
IT1191200B (en) 1988-02-24
FR2508043A1 (en) 1982-12-24
CA1270253A (en) 1990-06-12
IT8267776A0 (en) 1982-06-17
IE53161B1 (en) 1988-08-03
DE3222840A1 (en) 1983-05-05
NL8202467A (en) 1983-01-17

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee