GB2156821A - Process for purifying chymopapain - Google Patents

Process for purifying chymopapain Download PDF

Info

Publication number: GB2156821A
Authority: GB; United Kingdom
Prior art keywords: chymopapain; issued; solution; crude; enzyme
Prior art date: 1984-04-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

GB08416926A

Other languages

English (en)

Other versions

GB8416926D0 (en

Inventor

Bedii N Oray

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

James W Simmons

Original Assignee

James W Simmons

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-04-03

Filing date

1984-07-03

Publication date

1985-10-16

1984-07-03 Application filed by James W Simmons filed Critical James W Simmons

1984-08-08 Publication of GB8416926D0 publication Critical patent/GB8416926D0/en

1985-10-16 Publication of GB2156821A publication Critical patent/GB2156821A/en

Status Withdrawn legal-status Critical Current

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/63—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from plants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96466—Cysteine endopeptidases (3.4.22)

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Botany (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Immunology (AREA)
Biophysics (AREA)
Analytical Chemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Medicines Containing Plant Substances (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

GB08416926A 1984-04-03 1984-07-03 Process for purifying chymopapain Withdrawn GB2156821A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US59635684A	1984-04-03	1984-04-03

Publications (2)

Publication Number	Publication Date
GB8416926D0 GB8416926D0 (en)	1984-08-08
GB2156821A true GB2156821A (en)	1985-10-16

Family

ID=24386988

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GB08416926A Withdrawn GB2156821A (en)	1984-04-03	1984-07-03	Process for purifying chymopapain

Country Status (8)

Country	Link
EP (1)	EP0175786A1 (es)
JP (1)	JPS61502444A (es)
AU (1)	AU4217885A (es)
ES (2)	ES8604303A1 (es)
FI (1)	FI854765A7 (es)
GB (1)	GB2156821A (es)
NO (1)	NO854823L (es)
WO (1)	WO1985004417A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2193720A (en) *	1986-08-15	1988-02-17	Agricultural & Food Res	Monoclonal antibody

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8909836D0 (en) *	1989-04-28	1989-06-14	Boots Co Plc	Therapeutic agent
CN114054301B (zh) *	2021-12-27	2022-06-24	南通世睿电力科技有限公司	一种电力设备堵漏用丙烯酸胶黏剂低温条件下施工工艺
WO2025057166A1 (en)	2023-09-14	2025-03-20	Herbarius Ltd	Composition and method for removing plaque from an artery

Citations (3)

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Publication number	Priority date	Publication date	Assignee	Title
US3558433A (en) *	1967-11-07	1971-01-26	Baxter Laboratories Inc	Process for purification of chymopapain
GB1512491A (en) *	1975-02-20	1978-06-01	Lek Tovarna Farmacevtskih	Process for obtaining pure proteolytically active enzymes from latex of carica papaya
EP0065395A2 (en) *	1981-05-13	1982-11-24	BOOTS-FLINT, INC. (a Delaware corp.)	Improved chymopapain and method for its production and use

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US3412150A (en) *	1965-01-15	1968-11-19	Navy Usa	Nalpha-benzoyl arginine p-nitroanilide hydrochloride
US3623955A (en) *	1968-08-14	1971-11-30	Monsanto Co	Purification and recovery of alkaline protease using cationic-exchange resin
FR2093139A5 (es) *	1970-06-03	1972-01-28	Roussel Uclaf
US4086139A (en) *	1976-04-09	1978-04-25	Gb Fermentation Industries Inc.	Differential inactivation of amylase in amylase-protease mixtures
US4390628A (en) *	1979-05-17	1983-06-28	De Forenede Bryggerier A/S	Process for isolating Cu, Zn-superoxide dismutase from aqueous solutions containing said enzyme together with accompanying proteins

1984
- 1984-07-03 GB GB08416926A patent/GB2156821A/en not_active Withdrawn
- 1984-08-09 ES ES535035A patent/ES8604303A1/es not_active Expired
1985
- 1985-04-02 AU AU42178/85A patent/AU4217885A/en not_active Abandoned
- 1985-04-02 WO PCT/US1985/000559 patent/WO1985004417A1/en not_active Ceased
- 1985-04-02 FI FI854765A patent/FI854765A7/fi not_active Application Discontinuation
- 1985-04-02 EP EP85902217A patent/EP0175786A1/en not_active Withdrawn
- 1985-04-02 JP JP60501768A patent/JPS61502444A/ja active Pending
- 1985-08-23 ES ES546394A patent/ES8700319A1/es not_active Expired
- 1985-11-29 NO NO854823A patent/NO854823L/no unknown

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3558433A (en) *	1967-11-07	1971-01-26	Baxter Laboratories Inc	Process for purification of chymopapain
GB1512491A (en) *	1975-02-20	1978-06-01	Lek Tovarna Farmacevtskih	Process for obtaining pure proteolytically active enzymes from latex of carica papaya
EP0065395A2 (en) *	1981-05-13	1982-11-24	BOOTS-FLINT, INC. (a Delaware corp.)	Improved chymopapain and method for its production and use
GB2098997A (en) *	1981-05-13	1982-12-01	Smith Lab Inc	Improved chymopapain and method for its production and use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF BIOLOGICAL CHEMISTRY, VOLUME 237 NUMBER 4, APRIL 1962, EBATA ET AL., CHYMOPAPAIN PAGES 1086 TO 1094 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2193720A (en) *	1986-08-15	1988-02-17	Agricultural & Food Res	Monoclonal antibody
GB2193720B (en) *	1986-08-15	1990-09-19	Agricultural & Food Res	Payaya proteinase b separation and uses

Also Published As

Publication number	Publication date
GB8416926D0 (en)	1984-08-08
FI854765L (fi)	1985-12-02
WO1985004417A1 (en)	1985-10-10
AU4217885A (en)	1985-11-01
FI854765A0 (fi)	1985-12-02
JPS61502444A (ja)	1986-10-30
EP0175786A1 (en)	1986-04-02
ES546394A0 (es)	1986-10-01
ES535035A0 (es)	1986-01-16
NO854823L (no)	1986-01-24
FI854765A7 (fi)	1985-12-02
ES8700319A1 (es)	1986-10-01
ES8604303A1 (es)	1986-01-16

Publication	Publication Date	Title
EP0610320B1 (en)	2004-01-21	Purified chitin deacetylase
Nagai	1973	Vertebrate collagenase: further characterization and the significance of its latent form in vivo
US5332503A (en)	1994-07-26	Process for purifying collagenase
US4470969A (en)	1984-09-11	Process for producing a concentrate of coagulation factors VII and VIIa
JPH11504225A (ja)	1999-04-20	組織を解離するための酵素組成物
JPS62138434A (ja)	1987-06-22	アルフア−１−プロテイナ−ゼ阻害剤の製造法
US4771036A (en)	1988-09-13	Method and ophthalmic composition for the prevention and reversal of cataracts
US5521154A (en)	1996-05-28	Imidoester cross-linked hemoglobin compositions
US6280729B1 (en)	2001-08-28	Preparation of factor IX
GB2156821A (en)	1985-10-16	Process for purifying chymopapain
FI106562B (fi)	2001-02-28	Menetelmä yhden veren hyytymistekijän aktivoimiseksi
CA2151257A1 (en)	1994-06-23	Dna encoding chitin deacetylase
EP0726311A1 (en)	1996-08-14	Human activated protein c preparation and process for producing the same
DE3486023T2 (de)	1993-06-24	Verfahren zur herstellung von urokinase zymogen.
JPH0694480B2 (ja)	1994-11-24	試薬および方法
Pacaud	1976	Purification of protease II from Escherichia coli by affinity chromatography and separation of two enzyme species from cells harvested at late log phase
EP0430637B1 (en)	1994-09-28	Fibrinolytic protein and production method thereof
JPH10507919A (ja)	1998-08-04	ヒト及び植物メチルトランスフェラーゼの製造及び用途
Iwamoto et al.	1988	Subunit structures of three human myeloperoxidases
US3793149A (en)	1974-02-19	Cell-bound keratinolytic enzymes or trichophyton mentagrophytes and process therefor
CA1335186C (en)	1995-04-11	Method for purifying tissue plasminogen activator
Karam et al.	1984	A rapid method for the purification of fatty acid synthetase from the yeast Saccharomyces cerevisiae
JPH07289256A (ja)	1995-11-07	アミノペプチダーゼおよびその生産方法
RU2111754C1 (ru)	1998-05-27	Способ выделения cu, zn-супероксиддисмутазы человека
Braun et al.	1995	[6] Cytochrome-c reductase/processing peptidase complex from potato mitochondria

Legal Events

Date	Code	Title	Description
1986-08-06	WAP	Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)