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GB2039739A - Medicament against glaucoma - Google Patents

Medicament against glaucoma

Info

Publication number
GB2039739A
GB2039739A GB8007253A GB8007253A GB2039739A GB 2039739 A GB2039739 A GB 2039739A GB 8007253 A GB8007253 A GB 8007253A GB 8007253 A GB8007253 A GB 8007253A GB 2039739 A GB2039739 A GB 2039739A
Authority
GB
United Kingdom
Prior art keywords
medicament against
against glaucoma
carbon
carbostyril
glaucoma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB8007253A
Other versions
GB2039739B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Publication of GB2039739A publication Critical patent/GB2039739A/en
Application granted granted Critical
Publication of GB2039739B publication Critical patent/GB2039739B/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/24Oxygen atoms attached in position 8
    • C07D215/26Alcohols; Ethers thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Quinoline Compounds (AREA)

Abstract

A medicament against glaucoma containing as an effective ingredient a carbostyril derivative having an intra- ocular pressure-suppressing action and being represented by the following general formula: <IMAGE> wherein R<1> and R<2> each represent a lower alkyl group, and the carbon-to- carbon bond between the 3-and 4- positions of the carbostyril skeleton is a single or double bond.
GB8007253A 1978-07-14 1979-07-13 Medicament against glaucoma Expired GB2039739B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8623178A JPS5513241A (en) 1978-07-14 1978-07-14 Remedy for glaucoma

Publications (2)

Publication Number Publication Date
GB2039739A true GB2039739A (en) 1980-08-20
GB2039739B GB2039739B (en) 1983-01-26

Family

ID=13881010

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8007253A Expired GB2039739B (en) 1978-07-14 1979-07-13 Medicament against glaucoma

Country Status (8)

Country Link
EP (1) EP0020765A1 (en)
JP (1) JPS5513241A (en)
CH (1) CH643143A5 (en)
DE (1) DE2952959C2 (en)
GB (1) GB2039739B (en)
NL (1) NL7920004A (en)
SE (1) SE451070B (en)
WO (1) WO1980000215A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU518814B2 (en) * 1979-01-30 1981-10-22 Otsuka Pharamaceutical Co. Glaucoma treatment
JPS57172004A (en) * 1981-04-17 1982-10-22 Nichireki Chem Ind Co Construction of bitminous thin layered pavement
FR2539413A1 (en) * 1983-01-17 1984-07-20 Pos Lab CARBOSTYRILOXIMINOPROPANOLAMINES USEFUL AS MEDICAMENTS AND PROCESS FOR THEIR PREPARATION
JPH0726362B2 (en) * 1985-04-08 1995-03-22 日瀝化学工業株式会社 Bituminous pavement construction method
WO1996004911A1 (en) * 1994-08-10 1996-02-22 Otsuka Pharmaceutical Co., Ltd. Method of preventing and treating ophthalmic inflammation and/or wound

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5310994B2 (en) * 1974-06-13 1978-04-18
US4026897A (en) * 1974-01-31 1977-05-31 Otsuka Pharmaceutical Company 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxycarbostyril derivatives
DK230476A (en) * 1976-05-26 1977-11-27 E H Sahlertz LIGHT SIGNS AND WRITING EQUIPMENT

Also Published As

Publication number Publication date
DE2952959T1 (en) 1981-01-08
SE8001981L (en) 1980-03-13
GB2039739B (en) 1983-01-26
JPS5513241A (en) 1980-01-30
SE451070B (en) 1987-08-31
CH643143A5 (en) 1984-05-30
DE2952959C2 (en) 1986-08-28
WO1980000215A1 (en) 1980-02-21
EP0020765A4 (en) 1980-12-02
JPS611007B2 (en) 1986-01-13
NL7920004A (en) 1980-05-30
EP0020765A1 (en) 1981-01-07

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19980713