GB2032434B - Process for the preparation of 6 - piperidino - 2,4 - diamino - pyrimidine - 3-oxide - Google Patents
Process for the preparation of 6 - piperidino - 2,4 - diamino - pyrimidine - 3-oxideInfo
- Publication number
- GB2032434B GB2032434B GB7936681A GB7936681A GB2032434B GB 2032434 B GB2032434 B GB 2032434B GB 7936681 A GB7936681 A GB 7936681A GB 7936681 A GB7936681 A GB 7936681A GB 2032434 B GB2032434 B GB 2032434B
- Authority
- GB
- United Kingdom
- Prior art keywords
- piperidino
- diamino
- pyrimidine
- oxide
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ZFMITUMMTDLWHR-UHFFFAOYSA-N Minoxidil Chemical compound NC1=[N+]([O-])C(N)=CC(N2CCCCC2)=N1 ZFMITUMMTDLWHR-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/50—Three nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU78EE2594A HU177601B (en) | 1978-10-27 | 1978-10-27 | New process for preparing 6-piperidino-2,4-diamino-pyrimidine-3-oxide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2032434A GB2032434A (en) | 1980-05-08 |
| GB2032434B true GB2032434B (en) | 1982-11-17 |
Family
ID=10995794
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7936681A Expired GB2032434B (en) | 1978-10-27 | 1979-10-23 | Process for the preparation of 6 - piperidino - 2,4 - diamino - pyrimidine - 3-oxide |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5559172A (en) |
| AT (1) | AT373246B (en) |
| CH (1) | CH642365A5 (en) |
| CS (1) | CS213398B2 (en) |
| DE (1) | DE2943161A1 (en) |
| DK (1) | DK454579A (en) |
| ES (1) | ES485457A1 (en) |
| FI (1) | FI793307A7 (en) |
| GB (1) | GB2032434B (en) |
| HU (1) | HU177601B (en) |
| PL (1) | PL119712B1 (en) |
| SE (1) | SE432596B (en) |
| SU (1) | SU913942A3 (en) |
| YU (1) | YU262579A (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1179344A (en) * | 1981-07-15 | 1984-12-11 | Jean-Claude Muller | Process for the preparation of 6-¬3,6-dihydro-1(2h)- pyridyl| pyrimidine-3-oxides |
| CH649291A5 (en) * | 1982-03-16 | 1985-05-15 | Hoffmann La Roche | DICARBAMATE. |
| HU196061B (en) * | 1986-07-10 | 1988-09-28 | Richter Gedeon Vegyeszet | Process for production of pirimidine-derivatives |
| HU196067B (en) * | 1986-07-10 | 1988-09-28 | Richter Gedeon Vegyeszet | Process for production of 6-amin-1,2-dihydro-1-hydroxi-2-imino-4-piperidin-piramidin |
| FI864046L (en) * | 1986-10-07 | 1988-04-08 | Farmos Oy | FOERFARANDE FOER FRAMSTAELLNING AV EN TERAPEUTISKT AKTIV FOERENING. |
| LU86958A1 (en) * | 1987-07-31 | 1989-03-08 | Oreal | SALTS OF THIAMORPHOLINONE CARBOXYLIC ACID AND 2,4-DIAMINO PYRIMIDINE DERIVATIVES, THEIR USE IN COSMETICS AND PHARMACY |
| LU86960A1 (en) * | 1987-07-31 | 1989-03-08 | Oreal | PROCESS FOR THE PREPARATION OF PIPERIDINO-6 DIAMINO-2,4 PYRIMIDINE OXIDE-3 AND NEW COMPOUNDS |
| JPH02225474A (en) * | 1989-01-04 | 1990-09-07 | Lonza Ag | Preparation of 2,4-diamino-6-piperidinyl-pyrimidine- 3-n-oxide |
-
1978
- 1978-10-27 HU HU78EE2594A patent/HU177601B/en not_active IP Right Cessation
-
1979
- 1979-10-17 SE SE7908629A patent/SE432596B/en unknown
- 1979-10-23 GB GB7936681A patent/GB2032434B/en not_active Expired
- 1979-10-23 AT AT0689879A patent/AT373246B/en not_active IP Right Cessation
- 1979-10-24 FI FI793307A patent/FI793307A7/en not_active Application Discontinuation
- 1979-10-25 CH CH958279A patent/CH642365A5/en not_active IP Right Cessation
- 1979-10-25 DE DE19792943161 patent/DE2943161A1/en not_active Withdrawn
- 1979-10-25 SU SU792830754A patent/SU913942A3/en active
- 1979-10-25 CS CS797272A patent/CS213398B2/en unknown
- 1979-10-26 ES ES485457A patent/ES485457A1/en not_active Expired
- 1979-10-26 YU YU02625/79A patent/YU262579A/en unknown
- 1979-10-26 DK DK454579A patent/DK454579A/en not_active Application Discontinuation
- 1979-10-26 PL PL1979219242A patent/PL119712B1/en unknown
- 1979-10-27 JP JP13829279A patent/JPS5559172A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HU177601B (en) | 1981-11-28 |
| PL219242A1 (en) | 1980-06-16 |
| SU913942A3 (en) | 1982-03-15 |
| DE2943161A1 (en) | 1980-05-08 |
| SE432596B (en) | 1984-04-09 |
| JPS5559172A (en) | 1980-05-02 |
| GB2032434A (en) | 1980-05-08 |
| PL119712B1 (en) | 1982-01-30 |
| CS213398B2 (en) | 1982-04-09 |
| ATA689879A (en) | 1983-05-15 |
| ES485457A1 (en) | 1980-10-01 |
| CH642365A5 (en) | 1984-04-13 |
| FI793307A7 (en) | 1981-01-01 |
| DK454579A (en) | 1980-04-28 |
| SE7908629L (en) | 1980-04-28 |
| AT373246B (en) | 1983-12-27 |
| YU262579A (en) | 1983-01-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |