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GB202309909D0 - Regulatory elements - Google Patents

Regulatory elements

Info

Publication number
GB202309909D0
GB202309909D0 GBGB2309909.6A GB202309909A GB202309909D0 GB 202309909 D0 GB202309909 D0 GB 202309909D0 GB 202309909 A GB202309909 A GB 202309909A GB 202309909 D0 GB202309909 D0 GB 202309909D0
Authority
GB
United Kingdom
Prior art keywords
regulatory elements
regulatory
elements
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB2309909.6A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purespring Therapeutics Ltd
Original Assignee
Purespring Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purespring Therapeutics Ltd filed Critical Purespring Therapeutics Ltd
Priority to GBGB2309909.6A priority Critical patent/GB202309909D0/en
Publication of GB202309909D0 publication Critical patent/GB202309909D0/en
Priority to CN202480042643.4A priority patent/CN121463961A/en
Priority to PCT/GB2024/051695 priority patent/WO2025003709A1/en
Priority to AU2024306574A priority patent/AU2024306574A1/en
Priority to IL325328A priority patent/IL325328A/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A61K48/0058—Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GBGB2309909.6A 2023-06-29 2023-06-29 Regulatory elements Ceased GB202309909D0 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GBGB2309909.6A GB202309909D0 (en) 2023-06-29 2023-06-29 Regulatory elements
CN202480042643.4A CN121463961A (en) 2023-06-29 2024-06-28 Adjustment element
PCT/GB2024/051695 WO2025003709A1 (en) 2023-06-29 2024-06-28 Regulatory elements
AU2024306574A AU2024306574A1 (en) 2023-06-29 2024-06-28 Regulatory elements
IL325328A IL325328A (en) 2023-06-29 2025-12-14 Regulatory elements

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB2309909.6A GB202309909D0 (en) 2023-06-29 2023-06-29 Regulatory elements

Publications (1)

Publication Number Publication Date
GB202309909D0 true GB202309909D0 (en) 2023-08-16

Family

ID=87556827

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB2309909.6A Ceased GB202309909D0 (en) 2023-06-29 2023-06-29 Regulatory elements

Country Status (5)

Country Link
CN (1) CN121463961A (en)
AU (1) AU2024306574A1 (en)
GB (1) GB202309909D0 (en)
IL (1) IL325328A (en)
WO (1) WO2025003709A1 (en)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69703974T2 (en) 1996-10-17 2001-07-19 Oxford Biomedica (Uk) Ltd., Oxford RETROVIRAL VECTORS
CA2312291A1 (en) * 1997-12-05 1999-06-17 The Immune Response Corporation Novel vectors and genes exhibiting increased expression
US8852936B2 (en) 2012-09-21 2014-10-07 Laurantis Pharma Oy Autologous lymph node transfer in combination with VEGF-C or VEGF-D growth factor therapy to treat lymphedema and to improve reconstructive surgery
WO2014077863A1 (en) * 2012-11-19 2014-05-22 Nature Technology Corporation Replicative minicircle vectors with improved expression
TW201506036A (en) 2013-08-14 2015-02-16 Laurantis Pharma Oy Therapeutic use of VEGF-C and CCBE1
GB202003618D0 (en) * 2020-03-12 2020-04-29 Univ Bristol Gene Therapy
GB202103470D0 (en) * 2021-03-12 2021-04-28 Univ Bristol Promoter
US20250002546A1 (en) * 2021-11-16 2025-01-02 Genprex, Inc. Vectors for Increasing NPRL2 Expression in Cancer Cells and Methods of Use Thereof
EP4273243A1 (en) 2022-05-02 2023-11-08 Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca Nucleic acid constructs and vectors for podocyte specific expression
JP2025535103A (en) * 2022-10-11 2025-10-22 メイラグティーエックス ユーケー アイアイ リミティド Nucleic acid regulatory elements for gene expression in the liver and methods of use

Also Published As

Publication number Publication date
IL325328A (en) 2026-02-01
AU2024306574A1 (en) 2026-01-15
CN121463961A (en) 2026-02-03
WO2025003709A1 (en) 2025-01-02

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)