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GB202201927D0 - Artificial microrna construct - Google Patents

Artificial microrna construct

Info

Publication number
GB202201927D0
GB202201927D0 GBGB2201927.7A GB202201927A GB202201927D0 GB 202201927 D0 GB202201927 D0 GB 202201927D0 GB 202201927 A GB202201927 A GB 202201927A GB 202201927 D0 GB202201927 D0 GB 202201927D0
Authority
GB
United Kingdom
Prior art keywords
artificial microrna
microrna construct
construct
artificial
microrna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB2201927.7A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kings College London
KING'S COLLEGE
Original Assignee
Kings College London
KING'S COLLEGE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kings College London, KING'S COLLEGE filed Critical Kings College London
Priority to GBGB2201927.7A priority Critical patent/GB202201927D0/en
Publication of GB202201927D0 publication Critical patent/GB202201927D0/en
Priority to PCT/EP2023/053529 priority patent/WO2023152382A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
    • C12N2310/141—MicroRNAs, miRNAs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GBGB2201927.7A 2022-02-14 2022-02-14 Artificial microrna construct Ceased GB202201927D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB2201927.7A GB202201927D0 (en) 2022-02-14 2022-02-14 Artificial microrna construct
PCT/EP2023/053529 WO2023152382A1 (en) 2022-02-14 2023-02-13 Artificial microrna construct

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB2201927.7A GB202201927D0 (en) 2022-02-14 2022-02-14 Artificial microrna construct

Publications (1)

Publication Number Publication Date
GB202201927D0 true GB202201927D0 (en) 2022-03-30

Family

ID=80820881

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB2201927.7A Ceased GB202201927D0 (en) 2022-02-14 2022-02-14 Artificial microrna construct

Country Status (2)

Country Link
GB (1) GB202201927D0 (en)
WO (1) WO2023152382A1 (en)

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
GB8601597D0 (en) 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
GB8809129D0 (en) 1988-04-18 1988-05-18 Celltech Ltd Recombinant dna methods vectors and host cells
US7446190B2 (en) 2002-05-28 2008-11-04 Sloan-Kettering Institute For Cancer Research Nucleic acids encoding chimeric T cell receptors
EP3472318B1 (en) * 2016-07-08 2023-09-06 Exuma Biotech Corp. Methods and compositions for transducing lymphocytes and regulating the activity thereof
CN107937428B (en) * 2017-11-28 2021-08-06 马晓冬 Construction method of carrier integrating functions of microRNA and CAR
AU2019244479B2 (en) * 2018-03-30 2024-12-19 Les Hopitaux Universitaires De Geneve Micro RNA expression constructs and uses thereof
AU2020247119A1 (en) * 2019-03-25 2021-09-23 Max-Delbrück-Centrum Für Molekulare Medizin In Der Helmholtz-Gemeinschaft Enhancement of cytolytic T-cell activity by inhibiting EBAG9
AU2020253538A1 (en) * 2019-04-03 2021-11-18 Precision Biosciences, Inc. Genetically-modified immune cells comprising a microRNA-adapted shRNA (shRNAmiR)
KR20220035326A (en) * 2019-05-02 2022-03-22 셀리아드 Cells with multiplexed inhibitory RNA
CN110760001B (en) * 2019-07-29 2023-03-24 浙江启新生物技术有限公司 Construction and application of chimeric antigen receptor T cell secreted by GM-CSF knockdown and neutralizing single-chain antibody thereof
CN112239759A (en) * 2020-10-28 2021-01-19 重庆斯德姆生物技术有限公司 MicroRNA for knocking down PD1 gene expression and construction of chimeric antigen receptor-T/NK cell thereof
AU2022205683A1 (en) * 2021-01-11 2023-07-06 Precigen, Inc. Chimeric receptor therapy
JP2024514933A (en) * 2021-04-23 2024-04-03 ベイラー カレッジ オブ メディスン CAR NKT expressing an artificial microRNA embedded SHRNA for downregulation of MHC class I and II expression
CN113337544B (en) * 2021-07-05 2023-04-14 北京中医药大学 Retroviral vector expressing CAR and microRNA and its application

Also Published As

Publication number Publication date
WO2023152382A1 (en) 2023-08-17

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)