GB2021100A - Heterocyclic amines - Google Patents
Heterocyclic aminesInfo
- Publication number
- GB2021100A GB2021100A GB7913104A GB7913104A GB2021100A GB 2021100 A GB2021100 A GB 2021100A GB 7913104 A GB7913104 A GB 7913104A GB 7913104 A GB7913104 A GB 7913104A GB 2021100 A GB2021100 A GB 2021100A
- Authority
- GB
- United Kingdom
- Prior art keywords
- heterocyclic amines
- represent
- acylimino
- imino
- sulphur
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 Heterocyclic amines Chemical class 0.000 title abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
- 230000005923 long-lasting effect Effects 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compounds of the general formula I <IMAGE> (in which R<1> and R<2> represent H, halogen or C1 to C4 alkyl or alkoxy, X represents oxygen, sulphur, imino, C2 to C4 acylimino, or methylene, n and m represent 1, 2 or 3 and P represents 2 or 3> and their physiologically acceptable acid addition salts have a long-lasting anti-hypertensive action.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19782816627 DE2816627A1 (en) | 1978-04-17 | 1978-04-17 | Antihypertensive isoindolinyl-amino-imidazoline - prepd. by reacting 2-amino-isoindoline with 2-alkylthio-2-imidazoline |
| JP53058878A JPS595231B2 (en) | 1978-05-19 | 1978-05-19 | Redox agent for wet desulfurization process |
| DE19792905501 DE2905501A1 (en) | 1979-02-14 | 1979-02-14 | Heterocyclic amine(s) with long lasting antihypertensive activity - e.g. 2-N-amino-iso:indolinyl-imidazoline |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2021100A true GB2021100A (en) | 1979-11-28 |
| GB2021100B GB2021100B (en) | 1982-08-25 |
Family
ID=27187521
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7913104A Expired GB2021100B (en) | 1978-04-17 | 1979-04-12 | Heterocyclic amines |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB2021100B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0238753A1 (en) * | 1985-11-30 | 1987-09-30 | Beecham Group Plc | N-substituted condensed polymethylene imine derivatives |
| EP0275639A1 (en) * | 1986-11-27 | 1988-07-27 | Beecham Group Plc | N-substituted cyclic amides, their preparation and pharmaceutical compositions containing them |
| US4847280A (en) * | 1985-05-28 | 1989-07-11 | Beecham Group Plc | Novel treatment |
| US4988720A (en) * | 1985-05-28 | 1991-01-29 | Beecham Group P.L.C. | Novel treatment of hyperglycaemia |
-
1979
- 1979-04-12 GB GB7913104A patent/GB2021100B/en not_active Expired
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4847280A (en) * | 1985-05-28 | 1989-07-11 | Beecham Group Plc | Novel treatment |
| EP0254777A3 (en) * | 1985-05-28 | 1989-11-08 | Beecham Group Plc | Use of imidazolinylaminoisoindolines and related compounds in the treatment of hyperglycaemia |
| EP0212783A3 (en) * | 1985-05-28 | 1989-12-13 | Beecham Group Plc | Use of imidazolinylaminoisoindolines and related compounds in the treatment of hyperglycaemia |
| AU592097B2 (en) * | 1985-05-28 | 1990-01-04 | Beecham Group Plc | Method for the treatment and/or prophylaxis of hyperglycaemia |
| US4988720A (en) * | 1985-05-28 | 1991-01-29 | Beecham Group P.L.C. | Novel treatment of hyperglycaemia |
| US5141933A (en) * | 1985-05-28 | 1992-08-25 | Beecham Group P.L.C. | Treatment for hyperglycaemia |
| EP0238753A1 (en) * | 1985-11-30 | 1987-09-30 | Beecham Group Plc | N-substituted condensed polymethylene imine derivatives |
| US4863946A (en) * | 1985-11-30 | 1989-09-05 | Beecham Group Plc | 2-[2H-(1,3-dihydroisoindole)alkylene]-4,5-dihydroimidazoles and pharmaceutical compositions thereof |
| EP0275639A1 (en) * | 1986-11-27 | 1988-07-27 | Beecham Group Plc | N-substituted cyclic amides, their preparation and pharmaceutical compositions containing them |
| US4918083A (en) * | 1986-11-27 | 1990-04-17 | Beecham Group P.L.C. | 4,5 Dihydroimidazole compounds which have useful pharmaceutical utility |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2021100B (en) | 1982-08-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |