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GB202016331D0 - Bicyclic peptide ligand drug conjugates - Google Patents

Bicyclic peptide ligand drug conjugates

Info

Publication number
GB202016331D0
GB202016331D0 GBGB2016331.7A GB202016331A GB202016331D0 GB 202016331 D0 GB202016331 D0 GB 202016331D0 GB 202016331 A GB202016331 A GB 202016331A GB 202016331 D0 GB202016331 D0 GB 202016331D0
Authority
GB
United Kingdom
Prior art keywords
drug conjugates
peptide ligand
ligand drug
bicyclic peptide
bicyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB2016331.7A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BicycleRD Ltd
Original Assignee
BicycleRD Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BicycleRD Ltd filed Critical BicycleRD Ltd
Priority to GBGB2016331.7A priority Critical patent/GB202016331D0/en
Publication of GB202016331D0 publication Critical patent/GB202016331D0/en
Priority to PCT/GB2021/052677 priority patent/WO2022079445A1/en
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489Metalloendopeptidases (3.4.24)
    • C12N9/6491Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GBGB2016331.7A 2020-10-15 2020-10-15 Bicyclic peptide ligand drug conjugates Ceased GB202016331D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB2016331.7A GB202016331D0 (en) 2020-10-15 2020-10-15 Bicyclic peptide ligand drug conjugates
PCT/GB2021/052677 WO2022079445A1 (en) 2020-10-15 2021-10-15 Bicyclic peptide ligand drug conjugates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB2016331.7A GB202016331D0 (en) 2020-10-15 2020-10-15 Bicyclic peptide ligand drug conjugates

Publications (1)

Publication Number Publication Date
GB202016331D0 true GB202016331D0 (en) 2020-12-02

Family

ID=73598424

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB2016331.7A Ceased GB202016331D0 (en) 2020-10-15 2020-10-15 Bicyclic peptide ligand drug conjugates

Country Status (2)

Country Link
GB (1) GB202016331D0 (en)
WO (1) WO2022079445A1 (en)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1452868A2 (en) 2003-02-27 2004-09-01 Pepscan Systems B.V. Method for selecting a candidate drug compound
PT2511297E (en) 2004-02-06 2015-08-24 Morphosys Ag Anti-cd38 human antibodies and uses therefor
PT1844337E (en) 2005-01-24 2014-04-03 Pepscan Systems Bv Binding compounds, immunogenic compounds and peptidomimetics
ES2383191T3 (en) 2008-02-05 2012-06-19 Medical Research Council Methods and compositions
RS61853B1 (en) 2014-10-29 2021-06-30 Bicyclerd Ltd Bicyclic peptide ligands specific for mt1-mmp
CA3091775A1 (en) * 2018-02-23 2019-08-29 Bicycletx Limited Multimeric bicyclic peptide ligands
JP7551500B2 (en) * 2018-04-04 2024-09-17 バイスクルテクス・リミテッド Heterotandem bicyclic peptide conjugates
US11180531B2 (en) * 2018-06-22 2021-11-23 Bicycletx Limited Bicyclic peptide ligands specific for Nectin-4
GB201900530D0 (en) * 2019-01-15 2019-03-06 Bicyclerd Ltd Bicyclic peptide ligands specific for CD38
CN114787197A (en) * 2019-08-13 2022-07-22 拜斯科技术开发有限公司 Modified multimeric bicyclic peptide ligands
GB201914872D0 (en) * 2019-10-15 2019-11-27 Bicycletx Ltd Bicyclic peptide ligand drug conjugates

Also Published As

Publication number Publication date
WO2022079445A1 (en) 2022-04-21

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)