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GB201810326D0 - Crystalline form of sacubitril, its preparation and use - Google Patents

Crystalline form of sacubitril, its preparation and use

Info

Publication number
GB201810326D0
GB201810326D0 GBGB1810326.7A GB201810326A GB201810326D0 GB 201810326 D0 GB201810326 D0 GB 201810326D0 GB 201810326 A GB201810326 A GB 201810326A GB 201810326 D0 GB201810326 D0 GB 201810326D0
Authority
GB
United Kingdom
Prior art keywords
sacubitril
preparation
crystalline form
crystalline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1810326.7A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson Matthey PLC
Original Assignee
Johnson Matthey PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson Matthey PLC filed Critical Johnson Matthey PLC
Priority to GBGB1810326.7A priority Critical patent/GB201810326D0/en
Publication of GB201810326D0 publication Critical patent/GB201810326D0/en
Priority to PCT/GB2019/051696 priority patent/WO2019243799A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GBGB1810326.7A 2018-06-22 2018-06-22 Crystalline form of sacubitril, its preparation and use Ceased GB201810326D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB1810326.7A GB201810326D0 (en) 2018-06-22 2018-06-22 Crystalline form of sacubitril, its preparation and use
PCT/GB2019/051696 WO2019243799A1 (en) 2018-06-22 2019-06-18 Crystalline form of sacubitril, its preparation and use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1810326.7A GB201810326D0 (en) 2018-06-22 2018-06-22 Crystalline form of sacubitril, its preparation and use

Publications (1)

Publication Number Publication Date
GB201810326D0 true GB201810326D0 (en) 2018-08-08

Family

ID=63042574

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1810326.7A Ceased GB201810326D0 (en) 2018-06-22 2018-06-22 Crystalline form of sacubitril, its preparation and use

Country Status (2)

Country Link
GB (1) GB201810326D0 (en)
WO (1) WO2019243799A1 (en)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5217996A (en) * 1992-01-22 1993-06-08 Ciba-Geigy Corporation Biaryl substituted 4-amino-butyric acid amides
AR057882A1 (en) 2005-11-09 2007-12-26 Novartis Ag DOUBLE ACTION COMPOUNDS OF ANGIOTENSIN RECEPTOR BLOCKERS AND NEUTRAL ENDOPEPTIDASE INHIBITORS
ES2966924T3 (en) * 2015-08-28 2024-04-25 Hetero Labs Ltd Procedure for the preparation of a dual-acting neprilysin-angiotensin receptor inhibitor compound
MX2018007129A (en) * 2015-12-11 2018-11-09 Zentiva Ks Solid forms of (2r,4s)-5-(biphenyl-4-yl)-4-[(3-carboxypropionyl)a mino]-2- -methylpentanoic acid ethyl ester, its salts and a preparation method.
WO2017191620A1 (en) * 2016-05-06 2017-11-09 Sun Pharmaceutical Industries Limited A crystalline form of a salt of sacubitril and a process of its preparation
EP3511317A4 (en) * 2016-09-07 2020-04-15 Noratech Pharmaceuticals, Inc. NEW CRYSTALLINE SODIUM SALT FORM OF SACUBITRIL
KR20180124428A (en) * 2017-05-11 2018-11-21 한미정밀화학주식회사 Crystalline form of sacubitril hemisodium salt, preparation method thereof, and pharmaceutical composition comprising the same
WO2019127994A1 (en) * 2017-12-27 2019-07-04 浙江天宇药业股份有限公司 Sacubitril sodium salt, eutectic of sacubitril free acid and acetic acid, crystal form thereof, method for preparing crystal form, and use thereof

Also Published As

Publication number Publication date
WO2019243799A1 (en) 2019-12-26

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)