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GB201721421D0 - Chimeric antigen receptor - Google Patents

Chimeric antigen receptor

Info

Publication number
GB201721421D0
GB201721421D0 GBGB1721421.4A GB201721421A GB201721421D0 GB 201721421 D0 GB201721421 D0 GB 201721421D0 GB 201721421 A GB201721421 A GB 201721421A GB 201721421 D0 GB201721421 D0 GB 201721421D0
Authority
GB
United Kingdom
Prior art keywords
antigen receptor
chimeric antigen
chimeric
receptor
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1721421.4A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCL Business Ltd
Original Assignee
UCL Business Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCL Business Ltd filed Critical UCL Business Ltd
Priority to GBGB1721421.4A priority Critical patent/GB201721421D0/en
Publication of GB201721421D0 publication Critical patent/GB201721421D0/en
Priority to PCT/GB2018/053691 priority patent/WO2019122875A1/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/624Disulfide-stabilized antibody (dsFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/33Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GBGB1721421.4A 2017-12-20 2017-12-20 Chimeric antigen receptor Ceased GB201721421D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB1721421.4A GB201721421D0 (en) 2017-12-20 2017-12-20 Chimeric antigen receptor
PCT/GB2018/053691 WO2019122875A1 (en) 2017-12-20 2018-12-19 Chimeric antigen receptor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1721421.4A GB201721421D0 (en) 2017-12-20 2017-12-20 Chimeric antigen receptor

Publications (1)

Publication Number Publication Date
GB201721421D0 true GB201721421D0 (en) 2018-01-31

Family

ID=61008668

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1721421.4A Ceased GB201721421D0 (en) 2017-12-20 2017-12-20 Chimeric antigen receptor

Country Status (2)

Country Link
GB (1) GB201721421D0 (en)
WO (1) WO2019122875A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022001799A (en) * 2019-08-15 2022-03-11 Janssen Biotech Inc MATERIALS AND METHODS FOR IMPROVED SINGLE-CHAIN VARIABLE FRAGMENTS.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2502934B1 (en) * 2011-03-24 2018-01-17 Universitätsmedizin der Johannes Gutenberg-Universität Mainz Single chain antigen recognizing constructs (scARCs) stabilized by the introduction of novel disulfide bonds
US20160280798A1 (en) * 2013-11-06 2016-09-29 The United States Of America, As Represented By The Secretary Department Of Health & Human Service Alk antibodies, conjugates, and chimeric antigen receptors, and their use
GB201405845D0 (en) * 2014-04-01 2014-05-14 Ucl Business Plc Signalling system
US20170049819A1 (en) * 2014-04-25 2017-02-23 Bluebird Bio, Inc. Kappa/lambda chimeric antigen receptors

Also Published As

Publication number Publication date
WO2019122875A1 (en) 2019-06-27

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)