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GB2017088A - Novel derivatives of eburnamonine - Google Patents

Novel derivatives of eburnamonine

Info

Publication number
GB2017088A
GB2017088A GB7905197A GB7905197A GB2017088A GB 2017088 A GB2017088 A GB 2017088A GB 7905197 A GB7905197 A GB 7905197A GB 7905197 A GB7905197 A GB 7905197A GB 2017088 A GB2017088 A GB 2017088A
Authority
GB
United Kingdom
Prior art keywords
acid
eburnamonine
novel derivatives
dihydroxybenzoic
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7905197A
Other versions
GB2017088B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB2017088A publication Critical patent/GB2017088A/en
Application granted granted Critical
Publication of GB2017088B publication Critical patent/GB2017088B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C07H11/04—Phosphates; Phosphites; Polyphosphates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126—Acids containing more than four carbon atoms
    • C07C53/128—Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/03—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/03—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
    • C07C65/05—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring o-Hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/105—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic
    • C07C65/11—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic with carboxyl groups on a condensed ring system containing two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Compounds having vasodilating activity, of the general formula: <IMAGE> wherein X is glucose-1-phosphate acid or a salt thereof, acetylsalicylic acid, pamoic acid, 2,4- dihydroxybenzoic acid, 3,5- dihydroxybenzoic acid pivalic acid or clofibric acid are prepared by salt formation.
GB7905197A 1978-02-15 1979-02-14 Derivatives of eburnamonine Expired GB2017088B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH167478 1978-02-15

Publications (2)

Publication Number Publication Date
GB2017088A true GB2017088A (en) 1979-10-03
GB2017088B GB2017088B (en) 1982-10-20

Family

ID=4215945

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7905197A Expired GB2017088B (en) 1978-02-15 1979-02-14 Derivatives of eburnamonine

Country Status (12)

Country Link
AT (1) AT368155B (en)
AU (1) AU523984B2 (en)
BE (1) BE874154A (en)
CA (1) CA1117939A (en)
DE (1) DE2905329A1 (en)
ES (1) ES477754A1 (en)
FR (1) FR2417511A1 (en)
GB (1) GB2017088B (en)
IT (1) IT1207171B (en)
NL (1) NL7901107A (en)
NZ (1) NZ189650A (en)
ZA (1) ZA79564B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2320896A4 (en) * 2008-07-03 2012-08-29 Osteogenex Inc Vinpocetine and eburnamonine derivatives for promoting bone growth

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU187139B (en) * 1982-06-30 1985-11-28 Richter Gedeon Vegyeszet Process for preparing new eburnan derivatives
ES8507140A1 (en) * 1984-05-10 1985-09-01 Covex Sa Citric-acid salt of (-)vinburnine and process for its preparation.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2085630A1 (en) * 1970-04-07 1971-12-31 Le Men Georges Vincamone compsn - having vasodilator ganglioplegic and antihistamine activity
FR2228471A2 (en) * 1973-05-09 1974-12-06 Synthelabo Medicaments contg aneburnan-type base and ascorbic acid - - with rapid resorption on oral administration
US4122179A (en) * 1976-06-03 1978-10-24 Enrico Corvi Mora Acid addition salts of vincamine and apovincamine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2320896A4 (en) * 2008-07-03 2012-08-29 Osteogenex Inc Vinpocetine and eburnamonine derivatives for promoting bone growth

Also Published As

Publication number Publication date
ATA114679A (en) 1982-01-15
IT7920203A0 (en) 1979-02-15
IT1207171B (en) 1989-05-17
ES477754A1 (en) 1979-07-16
AU4424679A (en) 1979-08-23
CA1117939A (en) 1982-02-09
AT368155B (en) 1982-09-27
NZ189650A (en) 1981-07-13
GB2017088B (en) 1982-10-20
ZA79564B (en) 1980-02-27
FR2417511A1 (en) 1979-09-14
NL7901107A (en) 1979-08-17
DE2905329A1 (en) 1979-08-16
AU523984B2 (en) 1982-08-26
BE874154A (en) 1979-05-29

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee