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GB201707342D0 - Imaging agents and methods - Google Patents

Imaging agents and methods

Info

Publication number
GB201707342D0
GB201707342D0 GBGB1707342.0A GB201707342A GB201707342D0 GB 201707342 D0 GB201707342 D0 GB 201707342D0 GB 201707342 A GB201707342 A GB 201707342A GB 201707342 D0 GB201707342 D0 GB 201707342D0
Authority
GB
United Kingdom
Prior art keywords
methods
imaging agents
imaging
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GBGB1707342.0A
Other versions
GB2567124A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vysoka Akola Chemicko-Technologicka V Praze
Original Assignee
Vysoka Akola Chemicko-Technologicka V Praze
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vysoka Akola Chemicko-Technologicka V Praze filed Critical Vysoka Akola Chemicko-Technologicka V Praze
Priority to GB1707342.0A priority Critical patent/GB2567124A/en
Priority to PCT/EP2017/062048 priority patent/WO2018206126A1/en
Publication of GB201707342D0 publication Critical patent/GB201707342D0/en
Publication of GB2567124A publication Critical patent/GB2567124A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032Methine dyes, e.g. cyanine dyes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/12Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain being branched "branched" means that the substituent on the polymethine chain forms a new conjugated system, e.g. most trinuclear cyanine dyes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5076Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving cell organelles, e.g. Golgi complex, endoplasmic reticulum
    • G01N33/5079Mitochondria

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GB1707342.0A 2017-05-08 2017-05-08 Imaging agents and methods Withdrawn GB2567124A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB1707342.0A GB2567124A (en) 2017-05-08 2017-05-08 Imaging agents and methods
PCT/EP2017/062048 WO2018206126A1 (en) 2017-05-08 2017-05-18 Imaging agents and methods

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1707342.0A GB2567124A (en) 2017-05-08 2017-05-08 Imaging agents and methods

Publications (2)

Publication Number Publication Date
GB201707342D0 true GB201707342D0 (en) 2017-06-21
GB2567124A GB2567124A (en) 2019-04-10

Family

ID=59065636

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1707342.0A Withdrawn GB2567124A (en) 2017-05-08 2017-05-08 Imaging agents and methods

Country Status (2)

Country Link
GB (1) GB2567124A (en)
WO (1) WO2018206126A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111675921B (en) * 2020-06-09 2021-12-14 河南大学 CYPY and its application in the preparation of antitumor drugs
CN111574499B (en) * 2020-06-09 2021-12-10 河南大学 Cy5-650 and application thereof in preparation of antitumor drugs
CN113429335B (en) * 2021-06-25 2023-05-16 安徽大学 Lysosome-targeted dual-response two-photon fluorescent probe and preparation method and application thereof
CN113773666A (en) * 2021-08-11 2021-12-10 大连理工大学 A class of triplet intersystem channelling cyanine dyes, preparation method and application thereof
CN114045045B (en) * 2021-10-26 2022-11-04 大连理工大学 A class of single-photon up-conversion pentamethyl tetracyanine photosensitive dyes, preparation method and application thereof
CZ310199B6 (en) * 2022-02-23 2024-11-13 Univerzita Karlova Polymethinum salts as inhibitors of dihydroorotate dehydrogenase
CN114736200B (en) * 2022-03-22 2024-08-16 大连理工大学 A type of heavy atom-free triplet photosensitizer based on thiopentamethine cyanine dye, preparation method and application thereof
CN114874638B (en) * 2022-06-23 2024-01-19 西安建筑科技大学 Meso-position substituted pentamethine cyanine dye, preparation method and application thereof, and fluorescent probe
CN116947823B (en) * 2023-07-25 2025-02-07 李哲 An organic small molecule with long afterglow luminescence properties and its biological application
CN117049992A (en) * 2023-08-23 2023-11-14 济南大学 A fluorescent probe for simultaneous monitoring of mitochondria and lysosomes and its preparation and application
CN117263928A (en) * 2023-09-20 2023-12-22 南通大学 A kind of fluorescent probe and its preparation method

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1560838B1 (en) 2002-08-23 2009-05-13 Illumina Cambridge Limited Labelled nucleotides
US8173819B2 (en) * 2005-09-02 2012-05-08 Visen Medical, Inc. Nicotinic and picolinic acid derived near-infrared fluorophores
WO2008109832A2 (en) * 2007-03-08 2008-09-12 Visen Medical, Inc. Viable near-infrared fluorochrome labeled cells and methods of making and using same
US8864821B2 (en) * 2008-11-26 2014-10-21 Visen Medical, Inc. Methods and compositions for identifying subjects at risk of developing stent thrombosis
EP2419478B1 (en) * 2009-04-17 2018-02-28 Li-Cor, Inc. Fluorescent imaging with substituted cyanine dyes
WO2012054749A1 (en) * 2010-10-20 2012-04-26 Li-Cor, Inc. Cyanine dyes and their conjugates
CZ304094B6 (en) 2011-12-01 2013-10-16 Vysoká skola chemicko-technologická v Praze Use of polymethionine salts as mitochondrial probes
CN114042171B (en) * 2012-03-30 2024-12-06 文森医学公司 Bacterial imaging agents and methods of use thereof
EP3062825B1 (en) * 2013-10-31 2022-08-24 Beth Israel Deaconess Medical Center Near-infrared fluorescent contrast bioimaging agents and methods of use thereof

Also Published As

Publication number Publication date
WO2018206126A1 (en) 2018-11-15
GB2567124A (en) 2019-04-10

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)