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GB201604182D0 - Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer - Google Patents

Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer

Info

Publication number
GB201604182D0
GB201604182D0 GBGB1604182.4A GB201604182A GB201604182D0 GB 201604182 D0 GB201604182 D0 GB 201604182D0 GB 201604182 A GB201604182 A GB 201604182A GB 201604182 D0 GB201604182 D0 GB 201604182D0
Authority
GB
United Kingdom
Prior art keywords
quinolin
imidazo
compounds
treating cancer
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1604182.4A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Priority to GBGB1604182.4A priority Critical patent/GB201604182D0/en
Publication of GB201604182D0 publication Critical patent/GB201604182D0/en
Priority to TW106108065A priority patent/TW201808948A/en
Priority to PCT/EP2017/055683 priority patent/WO2017153578A1/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GBGB1604182.4A 2016-03-11 2016-03-11 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer Ceased GB201604182D0 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GBGB1604182.4A GB201604182D0 (en) 2016-03-11 2016-03-11 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer
TW106108065A TW201808948A (en) 2016-03-11 2017-03-10 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer
PCT/EP2017/055683 WO2017153578A1 (en) 2016-03-11 2017-03-10 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1604182.4A GB201604182D0 (en) 2016-03-11 2016-03-11 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer

Publications (1)

Publication Number Publication Date
GB201604182D0 true GB201604182D0 (en) 2016-04-27

Family

ID=55952185

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1604182.4A Ceased GB201604182D0 (en) 2016-03-11 2016-03-11 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer

Country Status (3)

Country Link
GB (1) GB201604182D0 (en)
TW (1) TW201808948A (en)
WO (1) WO2017153578A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021139814A1 (en) * 2020-01-09 2021-07-15 南京明德新药研发有限公司 Quinoline imidazole compound and application thereof
EP4171651A1 (en) 2020-06-24 2023-05-03 AstraZeneca UK Limited Combination of antibody-drug conjugate and atm inhibitor
JP7669473B2 (en) * 2020-09-21 2025-04-28 ウェイ ジョン Substituted 1-(3,3-difluoropiperidin-4-yl)-imidazo[4,5-c]quinolin-2-one compounds having blood-brain barrier permeability
EP3992191A1 (en) 2020-11-03 2022-05-04 Deutsches Krebsforschungszentrum Imidazo[4,5-c]quinoline compounds and their use as atm kinase inhibitors
WO2022128833A1 (en) 2020-12-15 2022-06-23 Merck Patent Gmbh Solid transition metal-ligand complexes
CN115232122B (en) * 2021-04-23 2024-05-31 石药集团中奇制药技术(石家庄)有限公司 Alkyne compound as well as preparation and application thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
AU719434B2 (en) 1996-02-13 2000-05-11 Astrazeneca Ab Quinazoline derivatives as VEGF inhibitors
ES2169355T3 (en) 1996-03-05 2002-07-01 Astrazeneca Ab DERIVATIVES OF 4-ANILINOQUINAZOLINA.
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
WO2010139747A1 (en) * 2009-06-04 2010-12-09 Novartis Ag 1H-IMIDAZO[4, 5-c]QUINOLINONE COMPOUNDS, USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES
CN102372711B (en) 2010-08-18 2014-09-17 山东轩竹医药科技有限公司 Imidazo quinoline PI3K and mTOR (mammalian target of rapamycin) dual inhibitor
CN102399218A (en) 2010-09-16 2012-04-04 和记黄埔医药(上海)有限公司 Triheterocyclic compounds and their use as PI3K inhibitors

Also Published As

Publication number Publication date
TW201808948A (en) 2018-03-16
WO2017153578A1 (en) 2017-09-14

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)