GB201401086D0 - Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders - Google Patents

Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders

Info

Publication number: GB201401086D0
Authority: GB; United Kingdom
Prior art keywords: treatment; pharmaceutical compositions; novel compounds; inflammatory disorders; disorders
Prior art date: 2014-01-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

GBGB1401086.2A

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Galapagos NV

Original Assignee

Galapagos NV

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-01-23

Filing date

2014-01-23

Publication date

2014-03-12

2014-01-23 Application filed by Galapagos NV filed Critical Galapagos NV

2014-01-23 Priority to GBGB1401086.2A priority Critical patent/GB201401086D0/en

2014-03-12 Publication of GB201401086D0 publication Critical patent/GB201401086D0/en

2015-01-19 Priority to EP18177201.3A priority patent/EP3395802A1/en

2015-01-19 Priority to SI201530383T priority patent/SI3097083T1/en

2015-01-19 Priority to DK15701945.6T priority patent/DK3097083T3/en

2015-01-19 Priority to HRP20181332TT priority patent/HRP20181332T1/en

2015-01-19 Priority to US14/599,644 priority patent/US9440929B2/en

2015-01-19 Priority to ES15701945.6T priority patent/ES2693019T3/en

2015-01-19 Priority to EP15701945.6A priority patent/EP3097083B1/en

2015-01-19 Priority to AU2015208269A priority patent/AU2015208269B2/en

2015-01-19 Priority to JP2016548110A priority patent/JP6472454B2/en

2015-01-19 Priority to CA2941474A priority patent/CA2941474A1/en

2015-01-19 Priority to EA201691468A priority patent/EA029827B1/en

2015-01-19 Priority to NZ72331315A priority patent/NZ723313A/en

2015-01-19 Priority to LTEP15701945.6T priority patent/LT3097083T/en

2015-01-19 Priority to MYPI2016702630A priority patent/MY180363A/en

2015-01-19 Priority to CN201580015662.9A priority patent/CN106132934B/en

2015-01-19 Priority to PL15701945T priority patent/PL3097083T3/en

2015-01-19 Priority to PT15701945T priority patent/PT3097083T/en

2015-01-19 Priority to BR112016016732-5A priority patent/BR112016016732B1/en

2015-01-19 Priority to PCT/EP2015/050850 priority patent/WO2015110378A1/en

2015-01-19 Priority to MX2016009442A priority patent/MX370546B/en

2015-01-19 Priority to HUE15701945A priority patent/HUE039450T2/en

2015-01-19 Priority to SG11201606971XA priority patent/SG11201606971XA/en

2015-01-22 Priority to TW104102159A priority patent/TWI689496B/en

2015-01-22 Priority to ARP150100176A priority patent/AR099160A1/en

2016-07-18 Priority to IL246823A priority patent/IL246823B/en

2016-08-23 Priority to PH12016501677A priority patent/PH12016501677B1/en

2016-09-12 Priority to US15/262,097 priority patent/US10179771B2/en

2018-08-23 Priority to US16/110,353 priority patent/US20190152922A1/en

2018-09-11 Priority to CY181100950T priority patent/CY1120679T1/en

Status Ceased legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Obesity (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Ophthalmology & Optometry (AREA)
Dermatology (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

GBGB1401086.2A 2014-01-23 2014-01-23 Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders Ceased GB201401086D0 (en)

Priority Applications (30)

Application Number	Priority Date	Filing Date	Title
GBGB1401086.2A GB201401086D0 (en)	2014-01-23	2014-01-23	Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders
PT15701945T PT3097083T (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
MYPI2016702630A MY180363A (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
CN201580015662.9A CN106132934B (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for treating inflammatory disorders
DK15701945.6T DK3097083T3 (en)	2014-01-23	2015-01-19	BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISEASES
HRP20181332TT HRP20181332T1 (en)	2014-01-23	2015-01-19	BENZIMIDAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL PREPARATIONS, INTENDED FOR THE TREATMENT OF INFLAMMATORY DISORDERS
US14/599,644 US9440929B2 (en)	2014-01-23	2015-01-19	Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders
ES15701945.6T ES2693019T3 (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory diseases
EP15701945.6A EP3097083B1 (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
AU2015208269A AU2015208269B2 (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
JP2016548110A JP6472454B2 (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory diseases
CA2941474A CA2941474A1 (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
EA201691468A EA029827B1 (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
NZ72331315A NZ723313A (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
LTEP15701945.6T LT3097083T (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
EP18177201.3A EP3395802A1 (en)	2014-01-23	2015-01-19	Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders
PL15701945T PL3097083T3 (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
HUE15701945A HUE039450T2 (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
SG11201606971XA SG11201606971XA (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
BR112016016732-5A BR112016016732B1 (en)	2014-01-23	2015-01-19	BENZIMIDAZOLE DERIVATIVES, THEIR USES, AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
PCT/EP2015/050850 WO2015110378A1 (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
MX2016009442A MX370546B (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders.
SI201530383T SI3097083T1 (en)	2014-01-23	2015-01-19	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
TW104102159A TWI689496B (en)	2014-01-23	2015-01-22	Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders
ARP150100176A AR099160A1 (en)	2014-01-23	2015-01-22	COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS OF THE SAME FOR THE TREATMENT OF INFLAMMATORY DISORDERS
IL246823A IL246823B (en)	2014-01-23	2016-07-18	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
PH12016501677A PH12016501677B1 (en)	2014-01-23	2016-08-23	Benzimidazole derivatives and pharmaceutical compositions thereof for the treatment of inflammatory disorders
US15/262,097 US10179771B2 (en)	2014-01-23	2016-09-12	Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders
US16/110,353 US20190152922A1 (en)	2014-01-23	2018-08-23	Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders
CY181100950T CY1120679T1 (en)	2014-01-23	2018-09-11	BENZIMIDAZOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS OF THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB1401086.2A GB201401086D0 (en)	2014-01-23	2014-01-23	Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders

Publications (1)

Publication Number	Publication Date
GB201401086D0 true GB201401086D0 (en)	2014-03-12

Family

ID=50287405

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GBGB1401086.2A Ceased GB201401086D0 (en)	2014-01-23	2014-01-23	Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders

Country Status (27)

Country	Link
US (3)	US9440929B2 (en)
EP (2)	EP3395802A1 (en)
JP (1)	JP6472454B2 (en)
CN (1)	CN106132934B (en)
AR (1)	AR099160A1 (en)
AU (1)	AU2015208269B2 (en)
BR (1)	BR112016016732B1 (en)
CA (1)	CA2941474A1 (en)
CY (1)	CY1120679T1 (en)
DK (1)	DK3097083T3 (en)
EA (1)	EA029827B1 (en)
ES (1)	ES2693019T3 (en)
GB (1)	GB201401086D0 (en)
HR (1)	HRP20181332T1 (en)
HU (1)	HUE039450T2 (en)
IL (1)	IL246823B (en)
LT (1)	LT3097083T (en)
MX (1)	MX370546B (en)
MY (1)	MY180363A (en)
NZ (1)	NZ723313A (en)
PH (1)	PH12016501677B1 (en)
PL (1)	PL3097083T3 (en)
PT (1)	PT3097083T (en)
SG (1)	SG11201606971XA (en)
SI (1)	SI3097083T1 (en)
TW (1)	TWI689496B (en)
WO (1)	WO2015110378A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR105400A1 (en) *	2015-08-04	2017-09-27	Lilly Co Eli	JAK1 INHIBITORS
LT3484875T (en) *	2016-07-14	2021-07-26	Eli Lilly And Company	PYRAZOLYLAMINOBENZIMIDAZOLE DERIVATIVES AS JAK INHIBITORS
GB201717260D0 (en) *	2017-10-20	2017-12-06	Galapagos Nv	Novel compounds and pharma ceutical compositions thereof for the treatment of inflammatory disorders
CN108355618B (en) *	2018-02-27	2020-09-08	江南大学	Bovine-derived hyaluronidase affinity medium and its adsorption method
CN108776121B (en) *	2018-04-08	2021-07-30	广州卡马生物科技有限公司	High-throughput screening method for antioxidant in medicinal materials based on fluorescence quenching principle
BR112021004051A2 (en) *	2018-09-18	2021-05-25	Terns, Inc.	compounds to treat certain leukemias
WO2020092015A1 (en)	2018-11-02	2020-05-07	University Of Rochester	Therapeutic mitigation of epithelial infection
GB201904373D0 (en) *	2019-03-29	2019-05-15	Galapagos Nv	Novel compounds and pharamaceutical compositions thereof for the treatment of inflammatory disorders
CN114671858B (en) *	2022-03-07	2023-08-08	华中师范大学	A kind of benzimidazole compound and its preparation method and application

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2360474B1 (en)	2004-06-21	2013-07-24	Galapagos N.V.	Methods and means for treatment of osteoarthritis
EP2226315A4 (en) *	2007-12-28	2012-01-25	Carna Biosciences Inc	2-AMINOQUINAZOLINE DERIVATIVE
EP2271631B1 (en) *	2008-04-22	2018-07-04	Portola Pharmaceuticals, Inc.	Inhibitors of protein kinases
KR20130141500A (en) *	2010-09-29	2013-12-26	크리스탈지노믹스(주)	Novel aminoquinazoline compound having a protein-kinase inhibiting action
UY34615A (en) *	2012-02-10	2013-09-30	Galapagos Nv	NEW USEFUL COMPOUNDS FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES.

2014
- 2014-01-23 GB GBGB1401086.2A patent/GB201401086D0/en not_active Ceased
2015
- 2015-01-19 SI SI201530383T patent/SI3097083T1/en unknown
- 2015-01-19 NZ NZ72331315A patent/NZ723313A/en not_active IP Right Cessation
- 2015-01-19 BR BR112016016732-5A patent/BR112016016732B1/en not_active IP Right Cessation
- 2015-01-19 PL PL15701945T patent/PL3097083T3/en unknown
- 2015-01-19 MY MYPI2016702630A patent/MY180363A/en unknown
- 2015-01-19 US US14/599,644 patent/US9440929B2/en active Active
- 2015-01-19 HR HRP20181332TT patent/HRP20181332T1/en unknown
- 2015-01-19 LT LTEP15701945.6T patent/LT3097083T/en unknown
- 2015-01-19 WO PCT/EP2015/050850 patent/WO2015110378A1/en not_active Ceased
- 2015-01-19 SG SG11201606971XA patent/SG11201606971XA/en unknown
- 2015-01-19 CN CN201580015662.9A patent/CN106132934B/en not_active Expired - Fee Related
- 2015-01-19 MX MX2016009442A patent/MX370546B/en active IP Right Grant
- 2015-01-19 PT PT15701945T patent/PT3097083T/en unknown
- 2015-01-19 ES ES15701945.6T patent/ES2693019T3/en active Active
- 2015-01-19 EA EA201691468A patent/EA029827B1/en not_active IP Right Cessation
- 2015-01-19 DK DK15701945.6T patent/DK3097083T3/en active
- 2015-01-19 EP EP18177201.3A patent/EP3395802A1/en not_active Withdrawn
- 2015-01-19 CA CA2941474A patent/CA2941474A1/en not_active Abandoned
- 2015-01-19 EP EP15701945.6A patent/EP3097083B1/en active Active
- 2015-01-19 JP JP2016548110A patent/JP6472454B2/en active Active
- 2015-01-19 HU HUE15701945A patent/HUE039450T2/en unknown
- 2015-01-19 AU AU2015208269A patent/AU2015208269B2/en not_active Ceased
- 2015-01-22 AR ARP150100176A patent/AR099160A1/en unknown
- 2015-01-22 TW TW104102159A patent/TWI689496B/en not_active IP Right Cessation
2016
- 2016-07-18 IL IL246823A patent/IL246823B/en active IP Right Grant
- 2016-08-23 PH PH12016501677A patent/PH12016501677B1/en unknown
- 2016-09-12 US US15/262,097 patent/US10179771B2/en active Active
2018
- 2018-08-23 US US16/110,353 patent/US20190152922A1/en not_active Abandoned
- 2018-09-11 CY CY181100950T patent/CY1120679T1/en unknown

Also Published As

Publication number	Publication date
MY180363A (en)	2020-11-28
HRP20181332T1 (en)	2018-10-19
CN106132934A (en)	2016-11-16
PT3097083T (en)	2018-10-26
WO2015110378A1 (en)	2015-07-30
JP2017503834A (en)	2017-02-02
US20190152922A1 (en)	2019-05-23
AU2015208269A1 (en)	2016-09-01
AU2015208269B2 (en)	2018-08-30
PH12016501677A1 (en)	2016-11-07
IL246823B (en)	2020-02-27
PH12016501677B1 (en)	2016-11-07
LT3097083T (en)	2018-11-26
SG11201606971XA (en)	2016-10-28
AR099160A1 (en)	2016-07-06
CY1120679T1 (en)	2019-12-11
US10179771B2 (en)	2019-01-15
CN106132934B (en)	2019-04-02
MX2016009442A (en)	2016-10-13
PL3097083T3 (en)	2018-11-30
SI3097083T1 (en)	2018-10-30
NZ723313A (en)	2019-11-29
TWI689496B (en)	2020-04-01
CA2941474A1 (en)	2015-07-30
EA029827B1 (en)	2018-05-31
TW201613873A (en)	2016-04-16
MX370546B (en)	2019-12-17
HUE039450T2 (en)	2018-12-28
EA201691468A1 (en)	2016-12-30
US20150203455A1 (en)	2015-07-23
EP3097083B1 (en)	2018-08-08
IL246823A0 (en)	2016-08-31
DK3097083T3 (en)	2018-10-01
EP3395802A1 (en)	2018-10-31
JP6472454B2 (en)	2019-02-20
EP3097083A1 (en)	2016-11-30
US9440929B2 (en)	2016-09-13
BR112016016732B1 (en)	2023-04-18
US20170057928A1 (en)	2017-03-02
BR112016016732A8 (en)	2020-06-16
ES2693019T3 (en)	2018-12-07

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IL246833A0 (en)	2016-08-31	Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders
IL256624B (en)	2019-09-26	Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders
IL255109A0 (en)	2017-12-31	Novel dihydropyridoisoquinolinones and pharmaceutical compositions thereof for the treatment of inflammatory disorders
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GB201411241D0 (en)	2014-08-06	Novel dihydropyridoisoquinolinones and pharmaceutical compositions thereof for the treatment of inflammatory disorders
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GB201518456D0 (en)	2015-12-02	Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory, autoimmune and/or proliferative diseases
GB201702603D0 (en)	2017-04-05	Novel compositions and pharmaceutical compositions thereof for the treatment of inflammatory disorders
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GB201702604D0 (en)	2017-04-05	Novel compositions and pharmaceutical compositions thereof for the treatment of inflammatory disorders

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2015-03-25	AT	Applications terminated before publication under section 16(1)