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GB201200259D0 - Novel therapies - Google Patents

Novel therapies

Info

Publication number
GB201200259D0
GB201200259D0 GB201200259A GB201200259A GB201200259D0 GB 201200259 D0 GB201200259 D0 GB 201200259D0 GB 201200259 A GB201200259 A GB 201200259A GB 201200259 A GB201200259 A GB 201200259A GB 201200259 D0 GB201200259 D0 GB 201200259D0
Authority
GB
United Kingdom
Prior art keywords
polypeptides
seq
acid sequence
amino acid
pollen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GB201200259A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Levin Karl C M
LINDSTEDT MALIN M
OHLIN PER M
Original Assignee
Levin Karl C M
LINDSTEDT MALIN M
OHLIN PER M
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Levin Karl C M, LINDSTEDT MALIN M, OHLIN PER M filed Critical Levin Karl C M
Priority to GB201200259A priority Critical patent/GB201200259D0/en
Publication of GB201200259D0 publication Critical patent/GB201200259D0/en
Priority to GB201212649A priority patent/GB201212649D0/en
Priority to PCT/GB2013/050032 priority patent/WO2013104901A2/en
Ceased legal-status Critical Current

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides hypoallergenic polypeptides comprising or consisting of a variant of the amino acid sequence of SEQ ID NO: 1 wherein one or more amino acids of SEQ 1 within an IgE-binding epitope is mutated and wherein the polypeptide exhibits reduced IgE-reactivity compared to a polypeptide consisting of the amino acid sequence of SEQ ID NO: 1. The invention further provides pharmaceutical compositions of such polypeptides, as well as methods for making and using said polypeptides, for example in the prevention of pollen grass allergies. Related aspects of the invention provide antibody polypeptides for passive immunisation against pollen grass allergies.
GB201200259A 2012-01-09 2012-01-09 Novel therapies Ceased GB201200259D0 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB201200259A GB201200259D0 (en) 2012-01-09 2012-01-09 Novel therapies
GB201212649A GB201212649D0 (en) 2012-01-09 2012-07-16 Novel therapies
PCT/GB2013/050032 WO2013104901A2 (en) 2012-01-09 2013-01-09 Novel therapies

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB201200259A GB201200259D0 (en) 2012-01-09 2012-01-09 Novel therapies

Publications (1)

Publication Number Publication Date
GB201200259D0 true GB201200259D0 (en) 2012-02-22

Family

ID=45788631

Family Applications (2)

Application Number Title Priority Date Filing Date
GB201200259A Ceased GB201200259D0 (en) 2012-01-09 2012-01-09 Novel therapies
GB201212649A Ceased GB201212649D0 (en) 2012-01-09 2012-07-16 Novel therapies

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB201212649A Ceased GB201212649D0 (en) 2012-01-09 2012-07-16 Novel therapies

Country Status (2)

Country Link
GB (2) GB201200259D0 (en)
WO (1) WO2013104901A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11013781B2 (en) 2015-07-01 2021-05-25 Alk-Abelló As Peptide combinations and uses thereof for treating grass allergy
WO2018026642A1 (en) * 2016-08-03 2018-02-08 The Feinstein Institute For Medical Research C1q and hmgb1 fusion proteins and uses thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8205892D0 (en) 1982-10-18 1982-10-18 Bror Morein IMMUNOGENT MEMBRANE PROTEIN COMPLEX, SET FOR PREPARATION AND USE THEREOF
SE8405493D0 (en) 1984-11-01 1984-11-01 Bror Morein IMMUNOGENT COMPLEX AND KITCHEN FOR PREPARING IT AND USING IT AS IMMUNOSTIMENTING AGENTS
EP0231039B1 (en) 1986-01-14 1992-01-08 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur Process for preparing immunological complexes and pharmaceutical composition containing these complexes
US4806352A (en) 1986-04-15 1989-02-21 Ribi Immunochem Research Inc. Immunological lipid emulsion adjuvant
WO1988006630A1 (en) 1987-03-02 1988-09-07 Genex Corporation Method for the preparation of binding molecules
US5643872A (en) 1989-10-23 1997-07-01 Smithkline Beecham Corporation Cyclic anti-aggregatory peptides
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
EP0614989A1 (en) 1993-02-17 1994-09-14 MorphoSys AG A method for in vivo selection of ligand-binding proteins
US6008058A (en) 1993-06-18 1999-12-28 University Of Louisville Cyclic peptide mixtures via side chain or backbone attachment and solid phase synthesis
SE9304060D0 (en) 1993-12-06 1993-12-06 Bioinvent Int Ab Methods to select specific bacteriophages
GB9716900D0 (en) 1997-08-08 1997-10-15 Bioinvent Int Ab Method for selecting phage displaying ligand binders
IT1318692B1 (en) * 2000-09-12 2003-08-27 Consiglio Nazionale Ricerche VARIATIONS OF ALLERGENIC PROTEINS OF PHLEUM PRATENSE.

Also Published As

Publication number Publication date
WO2013104901A3 (en) 2013-12-05
WO2013104901A2 (en) 2013-07-18
GB201212649D0 (en) 2012-08-29

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)